Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   LUZ02_RS07130 Genome accession   NZ_CP089491
Coordinates   1503390..1504739 (+) Length   449 a.a.
NCBI ID   WP_000815638.1    Uniprot ID   Q53IL8
Organism   Staphylococcus aureus strain 0242_IV_ST30     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 1496539..1513154 1503390..1504739 within 0


Gene organization within MGE regions


Location: 1496539..1513154
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUZ02_RS07100 - 1496539..1497036 (-) 498 WP_000051479.1 hypothetical protein -
  LUZ02_RS07105 - 1497505..1497882 (-) 378 WP_000687965.1 hypothetical protein -
  LUZ02_RS07110 - 1498308..1499240 (-) 933 WP_000364405.1 hypothetical protein -
  LUZ02_RS07115 - 1499312..1500895 (-) 1584 WP_000271876.1 hypothetical protein -
  LUZ02_RS07120 ssb 1501067..1501363 (+) 297 WP_000221966.1 cassette chromosome ssDNA-binding protein -
  LUZ02_RS07125 cch1 1501363..1503156 (+) 1794 WP_000195099.1 cassette chromosome replicative helicase -
  LUZ02_RS07130 ccrA 1503390..1504739 (+) 1350 WP_000815638.1 cassette chromosome recombinase CcrA Machinery gene
  LUZ02_RS07135 ccrB 1504761..1506389 (+) 1629 WP_001186608.1 cassette chromosome recombinase CcrB Machinery gene
  LUZ02_RS07140 - 1506911..1507261 (+) 351 WP_000849672.1 SAUGI family uracil-DNA glycosylase inhibitor -
  LUZ02_RS07145 - 1507348..1507659 (+) 312 WP_000700851.1 DUF960 family protein -
  LUZ02_RS07150 - 1507674..1508180 (+) 507 WP_050956976.1 DUF1643 domain-containing protein -
  LUZ02_RS07155 - 1508229..1509839 (+) 1611 Protein_1407 IS1182 family transposase -
  LUZ02_RS07160 - 1509830..1510072 (-) 243 Protein_1408 type I restriction enzyme endonuclease domain-containing protein -
  LUZ02_RS07165 - 1510062..1511048 (-) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  LUZ02_RS07170 mecA 1511145..1513154 (+) 2010 WP_063852655.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52636.23 Da        Isoelectric Point: 9.9639

>NTDB_id=637428 LUZ02_RS07130 WP_000815638.1 1503390..1504739(+) (ccrA) [Staphylococcus aureus strain 0242_IV_ST30]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQITQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYDYH
HGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRSQKQTKQTSSDNQLKQKIKCPCCNATLTNMTIRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKSAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHIIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=637428 LUZ02_RS07130 WP_000815638.1 1503390..1504739(+) (ccrA) [Staphylococcus aureus strain 0242_IV_ST30]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGTCGCAAAGATAATCGTAGTGGGT
ATCGACAAATAACACAATTAATTCAACAAGGACAGTGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACGTACCATGTTCATATCTTAAGCGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACACATGCACCTTTTGGTTACGATTATCAC
CACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGCCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATCGCAAAAACAAACCAAACAGACATCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCATTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAAGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAGCAAACACAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGGCATCAAATACAACACATCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATTGTCAATCAAACCATGCAATCATCGATTGCATAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase (Recombinase)

(169-250)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-321)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q53IL8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus N315

97.55

100

0.976
  ccrA Staphylococcus aureus COL

75.501

100

0.755