Detailed information NTG0637326

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: LUZ03_RS00500
• Genome accession: NZ_CP089487
• Coordinates: 87939..88982 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 0220_II_ST5
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 82939..93982

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LUZ03_RS00470	-	83309..83419 (+)	111	WP_001790257.1	hypothetical protein	-
LUZ03_RS00475	-	83448..83861 (+)	414	WP_078168791.1	hypothetical protein	-
LUZ03_RS00480	-	84292..85278 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
LUZ03_RS00485	map	85865..86623 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
LUZ03_RS00490	-	86840..87226 (+)	387	WP_001110179.1	hypothetical protein	-
LUZ03_RS00495	liaF	87241..87942 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
LUZ03_RS00500	vraS	87939..88982 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
LUZ03_RS00505	vraR	88972..89601 (+)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
LUZ03_RS00510	-	89717..90934 (-)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
LUZ03_RS00515	-	91212..91487 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
LUZ03_RS00520	-	91494..91958 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
LUZ03_RS00525	-	92105..92305 (+)	201	WP_000180461.1	DUF1128 family protein	-
LUZ03_RS00530	-	92308..93564 (+)	1257	WP_001795438.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=637326 LUZ03_RS00500 WP_001017131.1 87939..88982(+) (vraS) [Staphylococcus aureus strain 0220_II_ST5]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=637326 LUZ03_RS00500 WP_001017131.1 87939..88982(+) (vraS) [Staphylococcus aureus strain 0220_II_ST5]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1