Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   LUY94_RS10350 Genome accession   NZ_CP089485
Coordinates   2078594..2080222 (+) Length   542 a.a.
NCBI ID   WP_001186602.1    Uniprot ID   Q9XB94
Organism   Staphylococcus aureus strain E1139_IV_ST45     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 2058706..2091908 2078594..2080222 within 0


Gene organization within MGE regions


Location: 2058706..2091908
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUY94_RS10245 - 2058706..2060631 (-) 1926 WP_002485723.1 heavy metal translocating P-type ATPase -
  LUY94_RS10250 - 2060961..2061287 (-) 327 WP_000391495.1 metalloregulator ArsR/SmtB family transcription factor -
  LUY94_RS10255 - 2061494..2061853 (+) 360 WP_001631039.1 hypothetical protein -
  LUY94_RS10260 - 2061965..2062303 (-) 339 Protein_1993 recombinase family protein -
  LUY94_RS10265 - 2062312..2062941 (+) 630 Protein_1994 hypothetical protein -
  LUY94_RS10270 ccrA 2063128..2064489 (+) 1362 WP_001631036.1 cassette chromosome recombinase CcrA Machinery gene
  LUY94_RS10275 ccrB 2064486..2066114 (+) 1629 WP_001631035.1 cassette chromosome recombinase CcrB Machinery gene
  LUY94_RS10280 - 2066615..2066965 (+) 351 WP_001631034.1 SAUGI family uracil-DNA glycosylase inhibitor -
  LUY94_RS10285 - 2067052..2067363 (+) 312 WP_001631033.1 DUF960 domain-containing protein -
  LUY94_RS10290 - 2067379..2067882 (+) 504 WP_001631032.1 DUF1643 domain-containing protein -
  LUY94_RS10295 - 2067897..2068117 (+) 221 Protein_2000 hypothetical protein -
  LUY94_RS10300 - 2068280..2068690 (+) 411 WP_001631031.1 DUF2871 domain-containing protein -
  LUY94_RS10305 - 2069362..2069859 (+) 498 WP_001631030.1 GNAT family N-acetyltransferase -
  LUY94_RS10310 - 2069918..2070178 (+) 261 Protein_2003 IS5/IS1182 family transposase -
  LUY94_RS10315 - 2070182..2071384 (-) 1203 WP_061731577.1 restriction endonuclease subunit S -
  LUY94_RS10320 - 2071377..2071520 (-) 144 WP_001631028.1 restriction endonuclease subunit R -
  LUY94_RS10325 - 2071849..2072778 (-) 930 WP_231923532.1 AAA family ATPase -
  LUY94_RS10330 - 2072762..2073532 (-) 771 WP_000767841.1 DUF6414 family protein -
  LUY94_RS10335 - 2073649..2075079 (+) 1431 WP_001008608.1 DUF6038 family protein -
  LUY94_RS10340 cch1 2075199..2076989 (+) 1791 WP_061731576.1 cassette chromosome replicative helicase -
  LUY94_RS10345 ccrA 2077223..2078572 (+) 1350 WP_061731575.1 cassette chromosome recombinase CcrA Machinery gene
  LUY94_RS10350 ccrB 2078594..2080222 (+) 1629 WP_001186602.1 cassette chromosome recombinase CcrB Machinery gene
  LUY94_RS10355 - 2080740..2081090 (+) 351 WP_000859155.1 SAUGI family uracil-DNA glycosylase inhibitor -
  LUY94_RS10360 - 2081177..2081488 (+) 312 WP_031786335.1 DUF960 domain-containing protein -
  LUY94_RS10365 - 2081506..2082012 (+) 507 WP_001092169.1 DUF1643 domain-containing protein -
  LUY94_RS10370 - 2082033..2082350 (+) 318 WP_000659050.1 JAB domain-containing protein -
  LUY94_RS10375 - 2082478..2083116 (-) 639 Protein_2016 sulfite exporter TauE/SafE family protein -
  LUY94_RS10380 cstR 2083116..2083376 (-) 261 WP_000220507.1 persulfide-sensing transcriptional repressor CstR -
  LUY94_RS10385 - 2083512..2084576 (+) 1065 WP_000438836.1 DsrE/DsrF/DrsH-like family protein -
  LUY94_RS10390 cstB 2084609..2085943 (+) 1335 Protein_2019 persulfide dioxygenase-sulfurtransferase CstB -
  LUY94_RS10395 - 2086057..2087187 (-) 1131 WP_010922808.1 ROK family transcriptional regulator -
  LUY94_RS10400 psm-mec 2087521..2087589 (+) 69 WP_014532405.1 phenol-soluble modulin PSM-mec -
  LUY94_RS10405 mecI 2087674..2088045 (-) 372 WP_000369214.1 mecA-type methicillin resistance repressor MecI -
  LUY94_RS10410 mecR1 2088045..2089802 (-) 1758 WP_000952923.1 beta-lactam sensor/signal transducer MecR1 -
  LUY94_RS10415 mecA 2089899..2091908 (+) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -

Sequence

Protein


Download         Length: 542 a.a.        Molecular weight: 62664.84 Da        Isoelectric Point: 9.8600

>NTDB_id=637317 LUY94_RS10350 WP_001186602.1 2078594..2080222(+) (ccrB) [Staphylococcus aureus strain E1139_IV_ST45]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI

Nucleotide


Download         Length: 1629 bp        

>NTDB_id=637317 LUY94_RS10350 WP_001186602.1 2078594..2080222(+) (ccrB) [Staphylococcus aureus strain E1139_IV_ST45]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACTATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG

Domains

Predicted by InterproScan.

Ogr/Delta-like zinc finger (Ogr_Delta)

(301-356)

Resolvase, N terminal domain (Resolvase)

(11-156)

Recombinase (Recombinase)

(180-280)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9XB94

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

100

100

1