Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   LUY97_RS10655 Genome accession   NZ_CP089483
Coordinates   2112918..2114546 (+) Length   542 a.a.
NCBI ID   WP_001631035.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 0104_III_ST239     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 2107138..2140340 2112918..2114546 within 0


Gene organization within MGE regions


Location: 2107138..2140340
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUY97_RS10625 - 2107138..2109063 (-) 1926 WP_002485723.1 heavy metal translocating P-type ATPase -
  LUY97_RS10630 - 2109393..2109719 (-) 327 WP_000391495.1 metalloregulator ArsR/SmtB family transcription factor -
  LUY97_RS10635 - 2109926..2110285 (+) 360 WP_001631039.1 hypothetical protein -
  LUY97_RS10640 - 2110397..2110735 (-) 339 Protein_2061 recombinase family protein -
  LUY97_RS10645 - 2110744..2111373 (+) 630 Protein_2062 hypothetical protein -
  LUY97_RS10650 ccrA 2111560..2112921 (+) 1362 WP_001631036.1 cassette chromosome recombinase CcrA Machinery gene
  LUY97_RS10655 ccrB 2112918..2114546 (+) 1629 WP_001631035.1 cassette chromosome recombinase CcrB Machinery gene
  LUY97_RS10660 - 2115047..2115397 (+) 351 WP_001631034.1 SAUGI family uracil-DNA glycosylase inhibitor -
  LUY97_RS10665 - 2115484..2115795 (+) 312 WP_001631033.1 DUF960 domain-containing protein -
  LUY97_RS10670 - 2115811..2116314 (+) 504 WP_001631032.1 DUF1643 domain-containing protein -
  LUY97_RS10675 - 2116329..2116549 (+) 221 Protein_2068 hypothetical protein -
  LUY97_RS10680 - 2116712..2117122 (+) 411 WP_001631031.1 DUF2871 domain-containing protein -
  LUY97_RS10685 - 2117794..2118291 (+) 498 WP_001631030.1 GNAT family N-acetyltransferase -
  LUY97_RS10690 - 2118350..2118610 (+) 261 Protein_2071 IS5/IS1182 family transposase -
  LUY97_RS10695 - 2118614..2119816 (-) 1203 WP_061731577.1 restriction endonuclease subunit S -
  LUY97_RS10700 - 2119809..2119952 (-) 144 WP_001631028.1 restriction endonuclease subunit R -
  LUY97_RS10705 - 2120281..2121210 (-) 930 WP_231923532.1 AAA family ATPase -
  LUY97_RS10710 - 2121194..2121964 (-) 771 WP_000767841.1 DUF6414 family protein -
  LUY97_RS10715 - 2122081..2123511 (+) 1431 WP_001008608.1 DUF6038 family protein -
  LUY97_RS10720 cch1 2123631..2125421 (+) 1791 WP_061731576.1 cassette chromosome replicative helicase -
  LUY97_RS10725 ccrA 2125655..2127004 (+) 1350 WP_061731575.1 cassette chromosome recombinase CcrA Machinery gene
  LUY97_RS10730 ccrB 2127026..2128654 (+) 1629 WP_001186602.1 cassette chromosome recombinase CcrB Machinery gene
  LUY97_RS10735 - 2129172..2129522 (+) 351 WP_000859155.1 SAUGI family uracil-DNA glycosylase inhibitor -
  LUY97_RS10740 - 2129609..2129920 (+) 312 WP_031786335.1 DUF960 domain-containing protein -
  LUY97_RS10745 - 2129938..2130444 (+) 507 WP_001092169.1 DUF1643 domain-containing protein -
  LUY97_RS10750 - 2130465..2130782 (+) 318 WP_000659050.1 JAB domain-containing protein -
  LUY97_RS10755 - 2130910..2131548 (-) 639 Protein_2084 sulfite exporter TauE/SafE family protein -
  LUY97_RS10760 cstR 2131548..2131808 (-) 261 WP_000220507.1 persulfide-sensing transcriptional repressor CstR -
  LUY97_RS10765 - 2131944..2133008 (+) 1065 WP_000438836.1 DsrE/DsrF/DrsH-like family protein -
  LUY97_RS10770 cstB 2133041..2134375 (+) 1335 Protein_2087 persulfide dioxygenase-sulfurtransferase CstB -
  LUY97_RS10775 - 2134489..2135619 (-) 1131 WP_010922808.1 ROK family transcriptional regulator -
  LUY97_RS10780 psm-mec 2135953..2136021 (+) 69 WP_014532405.1 phenol-soluble modulin PSM-mec -
  LUY97_RS10785 mecI 2136106..2136477 (-) 372 WP_000369214.1 mecA-type methicillin resistance repressor MecI -
  LUY97_RS10790 mecR1 2136477..2138234 (-) 1758 WP_000952923.1 beta-lactam sensor/signal transducer MecR1 -
  LUY97_RS10795 mecA 2138331..2140340 (+) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -

Sequence

Protein


Download         Length: 542 a.a.        Molecular weight: 62474.71 Da        Isoelectric Point: 9.6103

>NTDB_id=637271 LUY97_RS10655 WP_001631035.1 2112918..2114546(+) (ccrB) [Staphylococcus aureus strain 0104_III_ST239]
MKQLKKKRIGLYARVSTEMQTDGYSIQGQLNQLTEYCQFQGYEVVNEYTDRGISGKTMQRPELQRMLKDANEGKLDCIMV
YKTNRLARNTSDLLNIVEELYKINVEFFSLTEKIEIASSTGKLMLQILASFAEFERNTIVENVYNGQRQRAIEGYYQGNL
PLGYDKVPDSKKELMINQHEANIVKYIFDSYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYIISNPFYIGKIQFAKY
RHWSDKRRKGLNEEPIIADGKHAPIIDRNLWDKVQFKRQESRKKPQVHGKGTNLLTGIVKCPKCGAAMAASNTTNTLKDG
TKKRIRYYSCSNFRNKGSKVCSANSVRADVLEKYVMDQILEIIKSKKVLKQLVEKVNEKSQIDVSSLNHDIAYKQSQCEE
IKAKMHTLTKTIEDSPDLDSVLKPTILSYQDELNQINNQIYQLEQDKQAEAPHYDADMIANVLQAIFKDIDKLEKSQLKS
LYLTIIDRIDIRKDEHHKKQFYVTLKLNNDIIKQLFNNHPLDEVLPSTSSLFLPQTLYITIE

Nucleotide


Download         Length: 1629 bp        

>NTDB_id=637271 LUY97_RS10655 WP_001631035.1 2112918..2114546(+) (ccrB) [Staphylococcus aureus strain 0104_III_ST239]
ATGAAACAACTCAAAAAGAAACGTATTGGATTATATGCACGTGTATCGACTGAAATGCAAACGGATGGTTACAGTATTCA
AGGTCAATTGAATCAACTTACAGAGTATTGTCAATTTCAAGGCTATGAAGTCGTCAATGAATACACCGATCGTGGTATAT
CAGGTAAAACAATGCAACGTCCAGAATTACAACGTATGTTAAAAGATGCCAACGAAGGTAAATTAGATTGTATTATGGTC
TACAAAACAAATCGTTTAGCTAGAAATACCTCAGATTTGTTAAATATTGTCGAGGAATTGTATAAGATTAATGTCGAATT
TTTTAGTCTAACTGAAAAAATAGAAATTGCCAGTTCAACAGGTAAATTGATGCTCCAAATTTTAGCCAGCTTCGCAGAAT
TTGAACGTAATACGATTGTAGAGAATGTCTACAATGGCCAAAGACAACGTGCTATTGAAGGTTATTATCAAGGTAATTTA
CCTCTAGGCTACGATAAAGTACCTGACAGTAAAAAAGAGCTCATGATCAATCAACATGAAGCGAATATTGTTAAATATAT
TTTTGATTCATACGCTAAAGGTCATGGTTATCGTAAGATTGCGAACGCATTGAATCATAAAGGTTATGTGACTAAGAAAG
GGAAACCTTTTAGTATTTCGTCCATTACCTACATCATCTCAAACCCTTTTTACATTGGAAAGATACAGTTTGCGAAGTAT
AGACACTGGAGCGATAAAAGACGAAAAGGACTCAATGAGGAACCGATTATCGCTGATGGTAAACATGCGCCTATTATTGA
TAGAAACCTATGGGATAAAGTACAGTTTAAACGTCAAGAGAGTCGCAAGAAACCACAAGTTCACGGCAAAGGAACAAACC
TACTGACTGGGATTGTAAAATGTCCGAAATGTGGTGCAGCAATGGCGGCAAGTAATACAACTAATACATTAAAAGATGGC
ACTAAGAAAAGAATCAGATATTACTCATGTAGCAATTTTAGAAATAAAGGTTCAAAAGTTTGTTCTGCCAATAGCGTTAG
AGCAGATGTACTAGAAAAATATGTTATGGATCAGATATTGGAAATTATCAAAAGCAAAAAGGTATTGAAGCAATTGGTTG
AAAAGGTAAATGAAAAAAGTCAAATAGACGTCTCTTCTTTGAACCATGATATTGCCTATAAACAGTCACAATGTGAAGAA
ATAAAAGCAAAAATGCATACATTAACGAAAACTATTGAAGACTCACCTGACTTAGATAGCGTATTAAAACCAACAATACT
TAGCTACCAAGATGAATTGAATCAAATAAATAATCAAATCTATCAACTAGAACAAGATAAACAAGCAGAAGCTCCACATT
ATGATGCTGATATGATTGCGAATGTACTACAAGCAATATTCAAAGATATAGACAAATTAGAGAAATCTCAGTTGAAATCA
CTATATCTAACAATCATCGATCGCATTGACATAAGAAAAGATGAGCATCATAAGAAGCAATTTTATGTTACGCTCAAGTT
AAATAATGATATAATCAAACAACTATTTAATAACCATCCACTCGACGAAGTGCTCCCTAGCACTTCGTCTTTATTTTTGC
CACAAACTTTATATATAACTATTGAATAA

Domains

Predicted by InterproScan.

Ogr/Delta-like zinc finger (Ogr_Delta)

(300-355)

Resolvase, N terminal domain (Resolvase)

(11-154)

Recombinase (Recombinase)

(179-280)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

72.694

100

0.727