Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   LUZ05_RS14635 Genome accession   NZ_CP089481
Coordinates   2912372..2913088 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain E1038_IIV_ST8     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2907372..2918088
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUZ05_RS14615 - 2908466..2909416 (+) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -
  LUZ05_RS14620 - 2909565..2911049 (+) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  LUZ05_RS14625 - 2911046..2912005 (+) 960 WP_001253312.1 carbohydrate kinase -
  LUZ05_RS14630 - 2912193..2912300 (-) 108 WP_001790167.1 hypothetical protein -
  LUZ05_RS14635 agrA 2912372..2913088 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  LUZ05_RS14640 agrC 2913107..2914399 (-) 1293 WP_001554031.1 quorum-sensing sensor histidine kinase AgrC -
  LUZ05_RS14645 agrD 2914424..2914564 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  LUZ05_RS14650 agrB 2914561..2915130 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  LUZ05_RS14655 hld 2915420..2915500 (+) 81 WP_000046022.1 delta-hemolysin -
  LUZ05_RS14660 - 2916097..2916882 (-) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  LUZ05_RS14665 - 2917243..2917869 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=637237 LUZ05_RS14635 WP_000688492.1 2912372..2913088(-) (agrA) [Staphylococcus aureus strain E1038_IIV_ST8]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=637237 LUZ05_RS14635 WP_000688492.1 2912372..2913088(-) (agrA) [Staphylococcus aureus strain E1038_IIV_ST8]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1