Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   U063_RS05635 Genome accession   NC_022886
Coordinates   1148283..1150067 (+) Length   594 a.a.
NCBI ID   WP_023592337.1    Uniprot ID   -
Organism   Helicobacter pylori BM012A     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1143283..1155067
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U063_RS05605 (U063_1120) motB 1144049..1144816 (+) 768 WP_023592334.1 flagellar motor protein MotB -
  U063_RS05610 (U063_1121) - 1144822..1145259 (+) 438 WP_001885597.1 hypothetical protein -
  U063_RS05615 (U063_1122) - 1145328..1146989 (+) 1662 WP_023592335.1 ABC transporter permease/substrate-binding protein -
  U063_RS05620 (U063_1123) - 1146993..1147634 (+) 642 WP_023592336.1 ATP-binding cassette domain-containing protein -
  U063_RS05625 - 1147646..1147825 (-) 180 WP_001872805.1 hypothetical protein -
  U063_RS05630 (U063_1124) - 1147817..1148278 (+) 462 WP_000437214.1 hypothetical protein -
  U063_RS05635 (U063_1125) uvrC 1148283..1150067 (+) 1785 WP_023592337.1 excinuclease ABC subunit UvrC Machinery gene
  U063_RS05640 (U063_1126) - 1150078..1151343 (+) 1266 WP_023592338.1 homoserine dehydrogenase -
  U063_RS05645 (U063_1127) - 1151344..1151688 (+) 345 WP_001211674.1 YraN family protein -
  U063_RS05650 (U063_1128) trxA 1151777..1152097 (+) 321 WP_000020204.1 thioredoxin -
  U063_RS05655 (U063_1129) trxB 1152102..1153037 (+) 936 WP_023592339.1 thioredoxin-disulfide reductase -
  U063_RS05660 (U063_1130) - 1153245..1154066 (+) 822 WP_023592340.1 glycosyltransferase family 25 protein -
  U063_RS05665 (U063_1131) - 1154271..1154519 (-) 249 WP_000790557.1 RNA-binding protein -
  U063_RS09000 - 1154673..1154864 (+) 192 Protein_1085 hypothetical protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68662.97 Da        Isoelectric Point: 9.8210

>NTDB_id=63701 U063_RS05635 WP_023592337.1 1148283..1150067(+) (uvrC) [Helicobacter pylori BM012A]
MADLLSSLKNLSSSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYSKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASHKAVLVKMFMRRGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLIPEQILLN
ACSNEALKELQDFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDT
SHHSNSQCVGGMVVYENNAFQKNSYRRYHLKGSDEYAQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIKKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=63701 U063_RS05635 WP_023592337.1 1148283..1150067(+) (uvrC) [Helicobacter pylori BM012A]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTAGTAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAACGCATCAAAAGCTATTTTTCCATCCGTAATAATGAAATCACGCCCA
ATCATCGTGCTAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTGGTTCAAAAGAAA
AATTGTATTAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTCAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTACAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCGCAAGCCATAAGGCGGT
GTTGGTGAAAATGTTTATGCGTAGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATACCAGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAGCGCTTAAAGAATTGCAAGATTTTATCTCTCATCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGACAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAACGCATTCCAAAAAAACTCTTATCGGCG
CTACCATTTAAAAGGCTCTGATGAATACGCTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCCAAAGAGC
CACCGCCTAATTTATGGGTGATTGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGCCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAATGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAAAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.811

100

0.978

Multiple sequence alignment