Detailed information NTG0635555

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: LTK16_RS01485
• Genome accession: NZ_CP089162
• Coordinates: 269675..270718 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain UNC_SaCF11
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 264675..275718

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LTK16_RS01455 (LTK16_01455)	-	265101..265211 (+)	111	WP_001790257.1	hypothetical protein	-
LTK16_RS01460 (LTK16_01460)	-	265240..265653 (+)	414	WP_001549145.1	hypothetical protein	-
LTK16_RS01465 (LTK16_01465)	-	266143..267129 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
LTK16_RS01470 (LTK16_01470)	map	267601..268359 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
LTK16_RS01475 (LTK16_01475)	-	268576..268962 (+)	387	WP_001110179.1	hypothetical protein	-
LTK16_RS01480 (LTK16_01480)	liaF	268977..269678 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
LTK16_RS01485 (LTK16_01485)	vraS	269675..270718 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
LTK16_RS01490 (LTK16_01490)	vraR	270708..271337 (+)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
LTK16_RS01495 (LTK16_01495)	-	271453..272670 (-)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
LTK16_RS01500 (LTK16_01500)	-	272948..273223 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
LTK16_RS01505 (LTK16_01505)	-	273230..273694 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
LTK16_RS01510 (LTK16_01510)	-	273841..274041 (+)	201	WP_000180461.1	DUF1128 family protein	-
LTK16_RS01515 (LTK16_01515)	-	274044..275300 (+)	1257	WP_001795438.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=635555 LTK16_RS01485 WP_001017131.1 269675..270718(+) (vraS) [Staphylococcus aureus strain UNC_SaCF11]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=635555 LTK16_RS01485 WP_001017131.1 269675..270718(+) (vraS) [Staphylococcus aureus strain UNC_SaCF11]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1