Detailed information NTG0635505

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: LTK20_RS11775
• Genome accession: NZ_CP089159
• Coordinates: 2328622..2329509 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain UNC_SaCF18
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2323622..2334509

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LTK20_RS11745 (LTK20_11745)	-	2324354..2325115 (+)	762	WP_000323455.1	alpha/beta hydrolase family protein	-
LTK20_RS11750 (LTK20_11750)	-	2325360..2325815 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
LTK20_RS14950	-	2325937..2326038 (+)	102	WP_000731972.1	SE2200 family small protein	-
LTK20_RS11760 (LTK20_11760)	-	2326098..2327522 (-)	1425	WP_000953744.1	alkaline phosphatase	-
LTK20_RS11765 (LTK20_11765)	-	2327720..2327920 (+)	201	WP_000604728.1	hypothetical protein	-
LTK20_RS11770 (LTK20_11770)	braR	2327946..2328611 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
LTK20_RS11775 (LTK20_11775)	braS	2328622..2329509 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
LTK20_RS11780 (LTK20_11780)	-	2329617..2330372 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
LTK20_RS11785 (LTK20_11785)	-	2330369..2332369 (+)	2001	WP_000776751.1	ABC transporter permease	-
LTK20_RS11790 (LTK20_11790)	-	2333028..2333141 (+)	114	WP_001791776.1	hypothetical protein	-
LTK20_RS11795 (LTK20_11795)	-	2333523..2333783 (+)	261	WP_001789910.1	hypothetical protein	-
LTK20_RS11800 (LTK20_11800)	-	2333793..2334290 (+)	498	WP_001065268.1	glutathione peroxidase	-
LTK20_RS11805 (LTK20_11805)	-	2334398..2334490 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=635505 LTK20_RS11775 WP_000143419.1 2328622..2329509(+) (braS) [Staphylococcus aureus strain UNC_SaCF18]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=635505 LTK20_RS11775 WP_000143419.1 2328622..2329509(+) (braS) [Staphylococcus aureus strain UNC_SaCF18]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997