Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   LPC11_RS04365 Genome accession   NZ_CP088218
Coordinates   906998..907714 (-) Length   238 a.a.
NCBI ID   WP_002466277.1    Uniprot ID   -
Organism   Staphylococcus sp. HL28     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 901998..912714
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPC11_RS04345 (LPC11_04345) - 902886..903110 (+) 225 WP_002452012.1 sulfurtransferase TusA family protein -
  LPC11_RS04350 (LPC11_04350) - 903250..904200 (+) 951 WP_023373246.1 LacI family DNA-binding transcriptional regulator -
  LPC11_RS04355 (LPC11_04355) - 904502..905986 (+) 1485 WP_114599611.1 sucrose-6-phosphate hydrolase -
  LPC11_RS04360 (LPC11_04360) - 905983..906939 (+) 957 WP_023373242.1 carbohydrate kinase -
  LPC11_RS04365 (LPC11_04365) agrA 906998..907714 (-) 717 WP_002466277.1 LytTR family DNA-binding domain-containing protein Regulator
  LPC11_RS04370 (LPC11_04370) - 907727..909016 (-) 1290 WP_023373241.1 GHKL domain-containing protein -
  LPC11_RS04375 (LPC11_04375) - 909044..909184 (-) 141 WP_023373239.1 cyclic lactone autoinducer peptide -
  LPC11_RS04380 (LPC11_04380) - 909189..909752 (-) 564 WP_041613618.1 accessory gene regulator AgrB -
  LPC11_RS04385 (LPC11_04385) - 910069..910146 (+) 78 WP_015364840.1 delta-lysin family phenol-soluble modulin -
  LPC11_RS04390 (LPC11_04390) - 910213..910290 (+) 78 WP_015364841.1 delta-lysin family phenol-soluble modulin -
  LPC11_RS04395 (LPC11_04395) - 910704..911489 (-) 786 WP_023373235.1 carbon-nitrogen family hydrolase -
  LPC11_RS04400 (LPC11_04400) - 911606..912232 (-) 627 WP_002466261.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27897.92 Da        Isoelectric Point: 5.9175

>NTDB_id=633311 LPC11_RS04365 WP_002466277.1 906998..907714(-) (agrA) [Staphylococcus sp. HL28]
MKIFICEDDPKQRENMASIIKNYIMIEEKPMELALATDDPYEVLEQSKNMNDIGCYFLDIQLEADINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELKTRIIDCLETAHTRLKLLSKESNVETIELKRGSNSVYVQYDDIM
FFESSSKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVINRRNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=633311 LPC11_RS04365 WP_002466277.1 906998..907714(-) (agrA) [Staphylococcus sp. HL28]
ATGAAAATATTCATTTGCGAAGATGATCCAAAACAACGAGAAAATATGGCTTCAATTATTAAAAATTATATTATGATTGA
GGAAAAGCCTATGGAGCTTGCTCTCGCAACTGATGATCCTTATGAAGTGCTTGAGCAATCCAAAAATATGAACGACATCG
GTTGTTATTTCTTAGATATTCAACTTGAAGCTGATATTAATGGCATTAAATTAGGTAGTGAAATTCGAAAACATGATCCC
GTAGGTAATATCATTTTTGTAACAAGTCATAGTGAATTAACATATCTCACTTTCGTTTATAAAGTGGCTGCAATGGATTT
TATATTCAAAGATGATCCTGCAGAACTGAAAACACGTATTATCGATTGTTTAGAAACAGCTCACACAAGACTCAAATTAT
TATCTAAAGAAAGTAATGTAGAAACAATTGAGTTAAAGCGTGGTAGTAATTCAGTTTATGTACAATATGACGATATTATG
TTTTTCGAATCATCTAGTAAATCACACCGATTAATTGCACATTTAGATAATAGACAAATCGAATTTTATGGTAATCTTAA
AGAATTAAGTCAATTAGATGATCGTTTCTTTAGATGCCATAATAGCTTTGTGATTAATAGGAGAAATATTGAGTCCATTG
ATTCTAAAGAACGCATTGTCTATTTTAAAAATAAAGAGCACTGTTATGCATCAGTTCGTAATGTCAAAAAGATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

93.697

100

0.937