Detailed information NTG0632271

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: LQF30_RS07475
• Genome accession: NZ_CP088002
• Coordinates: 1541727..1542773 (-)
• Length: 348 a.a.
• NCBI ID: WP_001830374.1
• Uniprot ID: A0A0N1EGU4
• Organism: Staphylococcus epidermidis strain IVK83
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1536727..1547773

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LQF30_RS07445 (LQF30_07430)	-	1537111..1538352 (-)	1242	WP_001832467.1	aminopeptidase	-
LQF30_RS07450 (LQF30_07435)	-	1538354..1538569 (-)	216	WP_001830421.1	DUF1128 domain-containing protein	-
LQF30_RS07455 (LQF30_07440)	-	1538710..1539174 (+)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
LQF30_RS07460 (LQF30_07445)	-	1539182..1539466 (+)	285	WP_001830401.1	YtxH domain-containing protein	-
LQF30_RS07465 (LQF30_07450)	-	1539873..1541051 (+)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
LQF30_RS07470 (LQF30_07455)	vraR	1541108..1541737 (-)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
LQF30_RS07475 (LQF30_07460)	vraS	1541727..1542773 (-)	1047	WP_001830374.1	sensor histidine kinase	Regulator
LQF30_RS07480 (LQF30_07465)	liaF	1542770..1543471 (-)	702	WP_002457093.1	cell wall-active antibiotics response protein LiaF	-
LQF30_RS07485 (LQF30_07470)	-	1543486..1543872 (-)	387	WP_001830382.1	hypothetical protein	-
LQF30_RS07490 (LQF30_07475)	map	1544030..1544785 (-)	756	WP_002457092.1	type I methionyl aminopeptidase	-
LQF30_RS07495 (LQF30_07480)	-	1544959..1545945 (+)	987	WP_002457091.1	aromatic acid exporter family protein	-
LQF30_RS07500 (LQF30_07485)	-	1546102..1547243 (+)	1142	WP_263925414.1	IS3 family transposase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40066.49 Da
• Isoelectric Point: 5.8512

>NTDB_id=632271 LQF30_RS07475 WP_001830374.1 1541727..1542773(-) (vraS) [Staphylococcus epidermidis strain IVK83]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=632271 LQF30_RS07475 WP_001830374.1 1541727..1542773(-) (vraS) [Staphylococcus epidermidis strain IVK83]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GGTTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0N1EGU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92