Detailed information NTG0063196

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: U471_RS16280
• Genome accession: NC_022653
• Coordinates: 3377500..3378663 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus amyloliquefaciens CC178
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3372500..3383663

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U471_RS16250 (U471_33860)	-	3372765..3373184 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
U471_RS16255 (U471_33870)	comFC	3373258..3373947 (-)	690	WP_197197403.1	phosphoribosyltransferase family protein	Machinery gene
U471_RS16260 (U471_33880)	-	3373953..3374237 (-)	285	WP_007407481.1	late competence development ComFB family protein	-
U471_RS16265 (U471_33890)	comFA	3374295..3375680 (-)	1386	WP_012118573.1	DEAD/DEAH box helicase	Machinery gene
U471_RS16270 (U471_33900)	-	3375788..3376636 (-)	849	WP_003151387.1	DegV family protein	-
U471_RS16275 (U471_33910)	degU	3376734..3377423 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
U471_RS16280 (U471_33920)	degS	3377500..3378663 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
U471_RS16285 (U471_33930)	-	3378886..3379533 (+)	648	WP_007614107.1	YigZ family protein	-
U471_RS16290 (U471_33940)	-	3379538..3380758 (+)	1221	WP_012118574.1	LCP family protein	-
U471_RS16295 (U471_33950)	-	3380857..3381933 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
U471_RS16300 (U471_33960)	tuaH	3382066..3383262 (-)	1197	WP_012118575.1	teichuronic acid biosynthesis protein TuaH	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=63196 U471_RS16280 WP_007407484.1 3377500..3378663(-) (degS) [Bacillus amyloliquefaciens CC178]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=63196 U471_RS16280 WP_007407484.1 3377500..3378663(-) (degS) [Bacillus amyloliquefaciens CC178]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTCGAAGAACTTAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGGGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951