Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   U471_RS05735 Genome accession   NC_022653
Coordinates   1125160..1125816 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus amyloliquefaciens CC178     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1120160..1130816
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U471_RS05710 (U471_11440) oppF 1120689..1121606 (+) 918 WP_012117283.1 oligopeptide ABC transporter ATP-binding protein OppF -
  U471_RS05715 (U471_11450) - 1121713..1122909 (+) 1197 WP_012117284.1 putative glycoside hydrolase -
  U471_RS05720 (U471_11460) - 1123018..1123596 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  U471_RS05725 (U471_11470) spx 1123775..1124170 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  U471_RS05730 (U471_11480) - 1124228..1124884 (-) 657 WP_012117285.1 TerC family protein -
  U471_RS19935 - 1125067..1125177 (+) 111 Protein_1089 adaptor protein MecA -
  U471_RS05735 (U471_11490) mecA 1125160..1125816 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  U471_RS05740 (U471_11500) - 1125967..1127127 (+) 1161 WP_012117286.1 competence protein CoiA family protein -
  U471_RS05745 (U471_11510) pepF 1127355..1129184 (+) 1830 WP_007409107.1 oligoendopeptidase F Regulator
  U471_RS19940 (U471_11520) - 1129222..1129389 (-) 168 WP_003155026.1 hypothetical protein -
  U471_RS05755 (U471_11530) spxH 1129675..1130577 (-) 903 WP_012117287.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=63155 U471_RS05735 WP_003155032.1 1125160..1125816(+) (mecA) [Bacillus amyloliquefaciens CC178]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=63155 U471_RS05735 WP_003155032.1 1125160..1125816(+) (mecA) [Bacillus amyloliquefaciens CC178]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
GGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment