Detailed information NTG0630287

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: LO764_RS14180
• Genome accession: NZ_CP087593
• Coordinates: 2780330..2781217 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain Newman NM-CQ
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2775330..2786217

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LO764_RS14150 (LO764_14150)	-	2775349..2775441 (+)	93	WP_010956583.1	hypothetical protein	-
LO764_RS14155 (LO764_14155)	-	2775549..2776046 (-)	498	WP_001065268.1	glutathione peroxidase	-
LO764_RS14160 (LO764_14160)	-	2776056..2776316 (-)	261	WP_001789910.1	hypothetical protein	-
LO764_RS14165 (LO764_14165)	-	2776698..2776811 (-)	114	WP_011447078.1	hypothetical protein	-
LO764_RS14170 (LO764_14170)	-	2777470..2779470 (-)	2001	WP_000776751.1	ABC transporter permease	-
LO764_RS14175 (LO764_14175)	-	2779467..2780222 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
LO764_RS14180 (LO764_14180)	braS	2780330..2781217 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
LO764_RS14185 (LO764_14185)	braR	2781228..2781893 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
LO764_RS14190 (LO764_14190)	-	2781919..2782119 (-)	201	WP_000604728.1	hypothetical protein	-
LO764_RS14195 (LO764_14195)	-	2782317..2783741 (+)	1425	WP_000953744.1	alkaline phosphatase	-
LO764_RS14730	-	2783801..2783902 (-)	102	WP_000731972.1	SE2200 family small protein	-
LO764_RS14205 (LO764_14205)	-	2784024..2784479 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
LO764_RS14210 (LO764_14210)	-	2784724..2785485 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=630287 LO764_RS14180 WP_000143419.1 2780330..2781217(-) (braS) [Staphylococcus aureus strain Newman NM-CQ]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=630287 LO764_RS14180 WP_000143419.1 2780330..2781217(-) (braS) [Staphylococcus aureus strain Newman NM-CQ]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997