Detailed information NTG0630281

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: LO764_RS10265
• Genome accession: NZ_CP087593
• Coordinates: 2034969..2036012 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain Newman NM-CQ
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2029969..2041012

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LO764_RS10235 (LO764_10235)	-	2030387..2031643 (-)	1257	WP_001795438.1	aminopeptidase	-
LO764_RS10240 (LO764_10240)	-	2031646..2031846 (-)	201	WP_000180461.1	DUF1128 family protein	-
LO764_RS10245 (LO764_10245)	-	2031993..2032457 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
LO764_RS10250 (LO764_10250)	-	2032464..2032739 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
LO764_RS10255 (LO764_10255)	-	2033017..2034234 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
LO764_RS10260 (LO764_10260)	vraR	2034350..2034979 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
LO764_RS10265 (LO764_10265)	vraS	2034969..2036012 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
LO764_RS10270 (LO764_10270)	liaF	2036009..2036710 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
LO764_RS10275 (LO764_10275)	-	2036725..2037111 (-)	387	WP_001110179.1	hypothetical protein	-
LO764_RS10280 (LO764_10280)	map	2037328..2038086 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
LO764_RS10285 (LO764_10285)	-	2038614..2039600 (+)	987	WP_000999713.1	FUSC family protein	-
LO764_RS10290 (LO764_10290)	-	2040090..2040503 (-)	414	WP_001549145.1	hypothetical protein	-
LO764_RS10295 (LO764_10295)	-	2040532..2040643 (-)	112	Protein_1994	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=630281 LO764_RS10265 WP_001017131.1 2034969..2036012(-) (vraS) [Staphylococcus aureus strain Newman NM-CQ]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=630281 LO764_RS10265 WP_001017131.1 2034969..2036012(-) (vraS) [Staphylococcus aureus strain Newman NM-CQ]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1