Detailed information NTG0062936

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: N596_RS00345
• Genome accession: NC_022584
• Coordinates: 51307..53574 (-)
• Length: 755 a.a.
• NCBI ID: WP_023022487.1
• Uniprot ID: -
• Organism: Streptococcus ilei
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 46307..58574

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
N596_RS00325 (N596_00325)	ileS	46700..49492 (+)	2793	WP_023026454.1	isoleucine--tRNA ligase	-
N596_RS00330 (N596_00330)	-	49708..50142 (+)	435	WP_023022484.1	GNAT family N-acetyltransferase	-
N596_RS00335 (N596_00335)	-	50227..50529 (-)	303	WP_006596776.1	DUF1827 family protein	-
N596_RS00340 (N596_00340)	-	50597..51046 (-)	450	WP_023022485.1	NUDIX hydrolase	-
N596_RS00345 (N596_00345)	clpE	51307..53574 (-)	2268	WP_023022487.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
N596_RS00350 (N596_00350)	-	53804..54034 (+)	231	WP_023026455.1	DUF1797 family protein	-
N596_RS00355 (N596_00355)	-	54345..55199 (+)	855	WP_023022489.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
N596_RS00360 (N596_00360)	-	55332..56213 (+)	882	WP_023026456.1	NAD(P)H-hydrate dehydratase	-
N596_RS00365 (N596_00365)	-	56241..57233 (+)	993	WP_023026458.1	LacI family DNA-binding transcriptional regulator	-

Sequence

Protein

• Length: 755 a.a.
• Molecular weight: 83993.03 Da
• Isoelectric Point: 4.8699

>NTDB_id=62936 N596_RS00345 WP_023022487.1 51307..53574(-) (clpE) [Streptococcus ilei]
MLCQNCKINDSTIHLYTNVNGHQQQVDLCQNCYQIMKTDPNNSLLAGLNQQNRGGRDPFEDFFNQLGNFQAPQEPQTPPT
QSGGGYGGGNGYGQNGNGRATGPNRPQAKQQPKGLLEEFGINVTEIARRGDIDPVIGRDDEILRVIEILNRRTKNNPVLI
GEPGVGKTAVVEGLAQKIVDGDVPYKLQDKEVIRLDVVSLVQGTGIRGQFEERMQQLMEEIRRREDVILFIDEIHEIVGA
GSAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVHYT
DGAIEAAALLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATRDEDFEKAAYFRDQIAKY
KEMQGQQVTDQDTPVISEKTIEHIVEQKTNIPVGDLKEKEQSQLINLAADLKAHVIGQDEAVEKIAKAIRRNRVGLGTPN
RPIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLIL
LDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKAEANVGFGAAREGRTNSVLGELGNFFSPEFM
NRFDGIIEFQPLSKENLLQIVTLMLDEVNQRLAQNEIHLDVTEKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYL
ENPNEKQLKAVMTSNGNISIKGKTKPANEAEKVTE

Nucleotide

• Length: 2268 bp

>NTDB_id=62936 N596_RS00345 WP_023022487.1 51307..53574(-) (clpE) [Streptococcus ilei]
ATGCTTTGTCAAAACTGTAAAATAAACGATTCAACCATTCATCTTTATACGAATGTGAATGGTCACCAACAACAAGTAGA
CCTTTGCCAGAACTGCTATCAAATTATGAAAACCGATCCTAACAATAGTCTCCTGGCAGGATTAAACCAACAAAATCGCG
GAGGGCGGGATCCTTTTGAAGATTTCTTCAATCAACTGGGCAACTTCCAAGCTCCCCAAGAACCTCAAACGCCACCGACC
CAATCAGGAGGAGGATATGGAGGTGGAAATGGCTACGGACAAAATGGGAACGGTCGAGCTACTGGACCAAATAGACCTCA
AGCCAAACAACAACCAAAAGGACTCCTAGAAGAGTTTGGAATTAATGTTACTGAAATCGCTCGCCGTGGGGACATTGATC
CAGTCATTGGCCGTGACGACGAAATTCTCCGAGTTATTGAAATTTTAAACCGCCGAACCAAAAACAACCCTGTTCTGATT
GGAGAACCTGGTGTCGGAAAAACAGCTGTCGTAGAGGGCCTGGCCCAGAAGATTGTCGATGGCGATGTCCCTTATAAATT
ACAAGACAAGGAAGTTATTCGGTTAGACGTTGTTAGCCTGGTTCAAGGGACTGGGATTCGTGGACAATTTGAAGAACGGA
TGCAACAACTAATGGAAGAAATCCGTCGCCGTGAAGATGTCATTTTGTTTATCGATGAAATCCATGAAATTGTAGGAGCA
GGATCTGCAGGTGATGGCAACATGGATGCAGGAAATATCCTCAAACCGGCTCTCGCTCGTGGTGAATTGCAATTAGTTGG
TGCCACAACACTCAATGAGTATCGTATTATCGAAAAAGATGCTGCTCTTGAACGCCGGATGCAACCAGTCAAGGTGGATG
AACCAACGGTTGAAGAAACCATTACCATCCTTAAAGGCATTCAAAAGAAATACGAAGACTACCACCACGTCCACTACACA
GATGGTGCTATTGAGGCTGCAGCTCTCCTCTCCAATCGCTATATCCAAGACCGCTTCTTGCCCGACAAAGCCATTGACCT
CTTGGACGAAGCAGGCTCTAAGATGAATTTGACCCTCAATTTTGTCGATCCCAAAGTCATTGACCAGCGCTTAATTGAAG
CCGAAAATCTCAAGGCCCAAGCGACGCGGGATGAAGATTTTGAAAAAGCAGCCTACTTCCGTGACCAAATCGCTAAGTAC
AAAGAAATGCAAGGGCAACAGGTCACCGACCAAGATACGCCCGTCATTAGCGAAAAGACTATCGAACACATTGTTGAGCA
AAAGACCAATATTCCAGTTGGAGATTTGAAAGAAAAAGAACAGTCTCAATTGATTAATTTGGCTGCTGATTTAAAAGCTC
ATGTCATCGGCCAAGATGAGGCTGTTGAAAAAATTGCTAAGGCTATCCGTCGTAATCGGGTAGGACTTGGAACGCCAAAC
CGTCCAATCGGTAGCTTCCTCTTTGTTGGACCAACTGGTGTCGGGAAGACCGAGTTGTCCAAGCAATTGGCCATCGAACT
CTTCGGTTCTGCTGATAGTATGATTCGCTTTGACATGAGTGAATACATGGAGAAACATGCCGTTGCCAAATTGGTCGGTG
CTCCTCCAGGTTATGTCGGCTATGAAGAAGCTGGCCAGCTGACTGAAAAAGTACGTCGCAACCCTTACTCTCTTATTCTT
CTAGATGAGGTAGAAAAGGCCCATCCTGATGTCATGCATATGTTCCTTCAAGTCTTAGATGATGGTCGCTTGACAGATGG
TCAAGGCCGTACCGTTAGCTTTAAAGATACGATTATCATCATGACCTCTAATGCTGGAACTGGCAAAGCGGAGGCCAATG
TTGGCTTTGGAGCAGCTCGTGAAGGTCGCACCAACTCTGTACTTGGAGAACTCGGGAACTTCTTTAGCCCTGAATTCATG
AACCGTTTTGATGGCATCATTGAATTCCAACCTCTCTCAAAAGAAAACCTGCTTCAAATCGTTACTCTCATGCTGGATGA
AGTCAATCAACGTCTCGCACAAAATGAGATTCATCTGGATGTGACAGAGAAGGTGAAAGAAAAATTGGTCGATCTGGGAT
ACGATCCAAAAATGGGGGCCCGCCCACTCCGTCGTACCATTCAAGACTATATTGAAGATGCGATTACCGATTACTACCTT
GAAAATCCAAATGAAAAACAACTCAAGGCAGTCATGACCAGCAATGGAAATATTAGCATTAAAGGAAAGACCAAACCTGC
AAACGAGGCAGAAAAAGTAACTGAATAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (652-725)

• AAA lid domain (AAA_lid_9) (296-393)

• ATPase family associated with various cellular activities (AAA) (AAA) (158-277)

• AAA domain (Cdc48 subfamily) (AAA_2) (481-644)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	86.508	100	0.866
clpE	Streptococcus pneumoniae D39	86.508	100	0.866
clpE	Streptococcus pneumoniae R6	86.508	100	0.866
clpE	Streptococcus pneumoniae TIGR4	86.508	100	0.866
clpE	Streptococcus mutans UA159	83.926	100	0.844
clpC	Lactococcus lactis subsp. cremoris KW2	76.455	100	0.766
clpC	Bacillus subtilis subsp. subtilis str. 168	50.661	90.199	0.457
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.325	83.046	0.401
clpC	Streptococcus pneumoniae Rx1	48.387	82.119	0.397
clpC	Streptococcus pneumoniae D39	48.387	82.119	0.397
clpC	Streptococcus pneumoniae TIGR4	48.226	82.119	0.396
clpC	Streptococcus thermophilus LMD-9	46.479	84.636	0.393
clpC	Streptococcus thermophilus LMG 18311	46.311	84.371	0.391
clpC	Streptococcus mutans UA159	47.504	82.252	0.391