Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA/pilA1   Type   Machinery gene
Locus tag   TthHC11_RS06565 Genome accession   NZ_AP019801
Coordinates   1220442..1220915 (+) Length   157 a.a.
NCBI ID   WP_143591260.1    Uniprot ID   -
Organism   Thermus thermophilus strain HC11     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1215442..1225915
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TthHC11_RS06540 (TthHC11_12750) ilvN 1216427..1216939 (-) 513 WP_096412614.1 acetolactate synthase small subunit -
  TthHC11_RS06545 (TthHC11_12760) ilvB 1216936..1218624 (-) 1689 WP_024119431.1 biosynthetic-type acetolactate synthase large subunit -
  TthHC11_RS06555 (TthHC11_12770) - 1218779..1219759 (-) 981 WP_024119432.1 YpdA family putative bacillithiol disulfide reductase -
  TthHC11_RS06560 (TthHC11_12780) pilA/pilA1 1219917..1220387 (+) 471 WP_011173283.1 GspH/FimT family protein Machinery gene
  TthHC11_RS06565 (TthHC11_12790) pilA/pilA1 1220442..1220915 (+) 474 WP_143591260.1 GspH/FimT family protein Machinery gene
  TthHC11_RS06570 (TthHC11_12800) pilA/pilA2 1220933..1221493 (+) 561 WP_242003979.1 type II secretion system protein Machinery gene
  TthHC11_RS06575 (TthHC11_12810) pilA/pilA3 1221490..1222191 (+) 702 WP_024119434.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  TthHC11_RS06580 (TthHC11_12820) comZ 1222202..1223866 (+) 1665 WP_143591261.1 pilus assembly PilX N-terminal domain-containing protein Machinery gene
  TthHC11_RS12010 (TthHC11_12830) pilA/pilA4 1224096..1224491 (+) 396 WP_011173287.1 type IV wide pilus major component PilA4 Machinery gene
  TthHC11_RS06590 - 1224548..1225840 (-) 1293 WP_143591263.1 hypothetical protein -

Sequence

Protein


Download         Length: 157 a.a.        Molecular weight: 16958.37 Da        Isoelectric Point: 10.3736

>NTDB_id=62899 TthHC11_RS06565 WP_143591260.1 1220442..1220915(+) (pilA/pilA1) [Thermus thermophilus strain HC11]
MRKPRGLSLIELVIVLAVLGVLLALGTGYLRSDRLAVNQAAQSLAAQVTRARIEAIRRNTFVGIQFSTQGAGGYLLFEDA
NRDSLYDSGEPVIQRVVFGQGDWTRVRLSAIEGPATLVFDPRGIPQGFAEARVSLSNRTGTYSQEISISPQGRASLP

Nucleotide


Download         Length: 474 bp        

>NTDB_id=62899 TthHC11_RS06565 WP_143591260.1 1220442..1220915(+) (pilA/pilA1) [Thermus thermophilus strain HC11]
ATGAGGAAGCCCCGTGGCCTAAGCCTCATAGAGCTCGTGATCGTCCTCGCCGTCCTGGGGGTCCTCCTGGCCCTGGGCAC
GGGCTACCTGCGCTCCGACCGCCTCGCCGTGAACCAGGCGGCCCAGTCCCTGGCAGCCCAGGTGACGCGGGCGAGGATCG
AGGCCATAAGGCGAAACACCTTCGTGGGAATCCAGTTCAGCACCCAAGGCGCAGGGGGCTACCTCCTCTTTGAGGACGCC
AATCGCGATAGCCTCTACGACTCCGGGGAGCCCGTGATCCAAAGGGTGGTTTTTGGCCAAGGGGACTGGACCAGGGTGCG
GCTCAGCGCCATTGAAGGCCCAGCAACCCTGGTCTTTGACCCCAGGGGCATACCCCAAGGCTTCGCCGAAGCCAGGGTAT
CCCTAAGCAACCGCACCGGAACCTACTCCCAAGAGATCTCCATAAGCCCCCAAGGGAGGGCGAGCCTGCCATGA

Domains

Predicted by InterProScan.

Type II transport protein GspH (GspH)

(40-152)

Prokaryotic N-terminal methylation motif (N_methyl)

(1-25)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA/pilA1 Thermus thermophilus HB27

53.543

80.892

0.433

Multiple sequence alignment