Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   N2A95_RS00460 Genome accession   NZ_CP104190
Coordinates   82036..84012 (+) Length   658 a.a.
NCBI ID   WP_003108928.1    Uniprot ID   A0ABP2SVQ8
Organism   Streptococcus parauberis strain HFTC0064     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 77036..89012
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N2A95_RS00425 (N2A95_00425) - 78049..78573 (-) 525 WP_003108914.1 hypothetical protein -
  N2A95_RS00430 (N2A95_00430) - 78577..78849 (-) 273 WP_003108915.1 AlpA family transcriptional regulator -
  N2A95_RS00435 (N2A95_00435) - 78862..79095 (-) 234 WP_003108917.1 hypothetical protein -
  N2A95_RS00440 (N2A95_00440) - 79083..79307 (-) 225 WP_003108919.1 hypothetical protein -
  N2A95_RS00445 (N2A95_00445) - 79567..79773 (-) 207 WP_003108921.1 helix-turn-helix transcriptional regulator -
  N2A95_RS11160 - 79891..80724 (+) 834 WP_003108923.1 helix-turn-helix domain-containing protein -
  N2A95_RS00455 (N2A95_00455) - 80794..81939 (+) 1146 WP_003108925.1 site-specific integrase -
  N2A95_RS00460 (N2A95_00460) hexB 82036..84012 (+) 1977 WP_003108928.1 DNA mismatch repair endonuclease MutL Machinery gene
  N2A95_RS00465 (N2A95_00465) - 84023..85246 (+) 1224 WP_003103803.1 MFS transporter -
  N2A95_RS00470 (N2A95_00470) ruvA 85248..85841 (+) 594 WP_003108930.1 Holliday junction branch migration protein RuvA Machinery gene
  N2A95_RS00475 (N2A95_00475) - 85845..86396 (+) 552 WP_096633379.1 DNA-3-methyladenine glycosylase I -
  N2A95_RS00480 (N2A95_00480) cinA 86785..88056 (+) 1272 WP_003108931.1 competence/damage-inducible protein A Machinery gene

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 73960.33 Da        Isoelectric Point: 5.1374

>NTDB_id=627483 N2A95_RS00460 WP_003108928.1 82036..84012(+) (hexB) [Streptococcus parauberis strain HFTC0064]
MQKIVELPEVLANQIAAGEVIERPASVVKELVENAIDAKSSQITIEIEESGLKSITITDNGDGMSKEDLPLSLLRHATSK
IKNQSDLFRIRTLGFRGEALPSIASISLLTIKSATAEADYGNQLISKGGEVESIEPVSTPVGTKIKVENLFFNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLICDGRELTKTSGTADLKQAIAGIYGINTAKKMVEISTADLDFEVSGFVSLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMSLISS
AISECLRLQDLIPDALENLAKSTTRNNNKFEQTSLPLQANKIYYDKEKGDFFTVDNRKEEPSNQPGQSNIVDSGVKIGDQ
VQPLVEETSPTFSVKHASRTISDVDDANHPDLDLSNQKKLTKLIENLENEETSVFPELDYFGQMHGTYLFAQGNGGLFII
DQHAAQERVKYEYYREKIGQVDNSLQQLLVPYLFEFSGSDFINLQEKMDLLNQVGIYLEEYGQNTFILREHPIWMKENEI
ESGVYEMCDMLLLTNNVSIKTYRAELAIMMSCKRSIKANHSLDDYSARQLLLQLAQCKNPYNCPHGRPVLINFSKADMEK
MFRRIQENHTSLRDLGKY

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=627483 N2A95_RS00460 WP_003108928.1 82036..84012(+) (hexB) [Streptococcus parauberis strain HFTC0064]
ATGCAAAAGATTGTAGAATTACCAGAGGTTCTCGCCAATCAGATCGCGGCTGGTGAAGTTATTGAACGGCCAGCAAGTGT
TGTGAAAGAATTGGTCGAGAATGCTATTGATGCCAAAAGCAGTCAAATTACAATTGAGATTGAAGAATCAGGACTTAAAT
CAATTACTATAACTGATAATGGGGATGGGATGTCAAAAGAAGACTTACCCCTTAGTTTGTTACGTCATGCAACCAGTAAG
ATAAAAAATCAAAGTGATCTTTTCAGAATTAGAACTTTGGGTTTCCGTGGTGAGGCTTTACCTTCAATTGCTTCTATCAG
TTTACTGACAATTAAATCAGCAACAGCTGAAGCAGACTATGGCAATCAACTAATCTCCAAGGGTGGAGAAGTTGAATCAA
TTGAACCAGTCTCAACGCCAGTTGGAACAAAGATAAAAGTTGAAAATCTCTTTTTCAACACGCCTGCTCGTTTAAAATAC
ATGAAGAGTCTGCAAGCTGAGCTTGCGCATATTGTCGATGTGGTCAATCGTCTTAGCTTAGCTCATCCAGAAGTAGCCTT
TACATTGATTTGTGATGGAAGGGAGTTAACTAAGACCTCAGGAACTGCTGATTTAAAACAAGCTATTGCAGGTATCTATG
GTATTAACACTGCGAAGAAAATGGTCGAGATTTCAACGGCAGATTTAGACTTTGAGGTTTCAGGCTTTGTTAGTTTACCC
GAATTAACAAGGGCAAATCGAAATTACATAACTATTTTAATCAATGGGCGTTATATCAAAAACTTTCTCTTGAACAGGGC
TATTTTAGATGGTTATGGATCAAAATTAATGGTTGGACGCTTTCCAATTGTCGTTATTGATATTCAAATCGATCCTTATT
TAGCTGATGTAAACGTCCACCCAACTAAACAGGAAGTGCGGATTTCAAAAGAACGTGAATTAATGAGTTTAATTAGTTCA
GCAATTTCAGAGTGTCTCCGTTTACAGGATTTGATTCCTGATGCCTTGGAAAATTTAGCCAAGTCAACGACAAGAAACAA
TAATAAATTTGAACAAACAAGTCTACCTTTACAAGCCAATAAAATTTACTATGATAAAGAAAAAGGTGATTTCTTTACAG
TTGATAATAGAAAAGAAGAGCCCTCTAACCAACCTGGTCAAAGTAATATAGTTGACAGCGGTGTAAAGATAGGTGACCAA
GTACAGCCTTTAGTTGAAGAGACAAGTCCAACATTCTCTGTCAAGCATGCTAGTCGCACGATAAGTGATGTGGATGATGC
CAATCATCCAGATTTGGATTTATCTAATCAGAAAAAATTAACAAAACTGATTGAAAATTTAGAGAACGAAGAAACTTCGG
TTTTCCCAGAGTTAGATTACTTTGGGCAAATGCATGGAACATATCTCTTTGCTCAGGGGAATGGTGGATTGTTTATCATT
GATCAACACGCTGCTCAAGAGCGTGTTAAATATGAGTATTATCGAGAAAAAATTGGTCAGGTCGACAATAGTTTGCAACA
ATTATTAGTTCCCTATCTCTTTGAATTTTCTGGGTCAGATTTTATTAATCTGCAAGAAAAGATGGATTTACTAAATCAAG
TTGGCATTTATCTAGAAGAATATGGACAAAATACCTTCATTCTCCGCGAACATCCAATTTGGATGAAGGAAAATGAAATT
GAATCTGGTGTCTATGAAATGTGTGATATGCTTTTGTTGACAAATAATGTGTCCATTAAAACTTATCGTGCAGAGTTAGC
CATCATGATGAGCTGTAAACGATCAATTAAAGCAAATCATAGTCTAGATGACTATTCAGCACGGCAATTACTATTGCAAC
TGGCACAATGTAAAAATCCATATAACTGTCCACATGGGCGACCTGTCTTGATTAATTTTAGTAAAGCGGATATGGAAAAA
ATGTTCCGACGGATACAAGAAAATCATACTAGCTTGAGAGATTTAGGAAAATATTAG

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(460-602)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-120)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

68.12

100

0.688