Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   LOD77_RS07770 Genome accession   NZ_CP086728
Coordinates   1517727..1519973 (+) Length   748 a.a.
NCBI ID   WP_274505301.1    Uniprot ID   -
Organism   Streptococcus parasuis strain SS20     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1512727..1524973
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LOD77_RS07745 (LOD77_07735) - 1513664..1514572 (+) 909 WP_274505299.1 neutral zinc metallopeptidase -
  LOD77_RS07750 (LOD77_07740) - 1514653..1515504 (-) 852 WP_274505300.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  LOD77_RS07755 (LOD77_07745) - 1515633..1516367 (-) 735 WP_130554560.1 amino acid ABC transporter ATP-binding protein -
  LOD77_RS07760 (LOD77_07750) - 1516375..1517049 (-) 675 WP_171989206.1 amino acid ABC transporter permease -
  LOD77_RS07765 (LOD77_07755) - 1517168..1517398 (-) 231 WP_024392448.1 DUF1797 family protein -
  LOD77_RS07770 (LOD77_07760) clpE 1517727..1519973 (+) 2247 WP_274505301.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  LOD77_RS07775 (LOD77_07765) - 1520120..1520587 (+) 468 WP_174845583.1 NUDIX hydrolase -
  LOD77_RS07780 (LOD77_07770) - 1520634..1520942 (+) 309 WP_171989209.1 DUF1827 family protein -
  LOD77_RS07785 (LOD77_07775) ileS 1521005..1523794 (-) 2790 WP_274505950.1 isoleucine--tRNA ligase -
  LOD77_RS07790 (LOD77_07780) - 1523805..1524248 (-) 444 WP_171989210.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 748 a.a.        Molecular weight: 83395.83 Da        Isoelectric Point: 5.2853

>NTDB_id=626207 LOD77_RS07770 WP_274505301.1 1517727..1519973(+) (clpE) [Streptococcus parasuis strain SS20]
MLCTNCKINDATIHLYTNMNGKQQKVDLCHNCYQIMKTDPNNAILRGLGENLTNPNNMDPFSEFFNHLGGYPGNTPAGKN
RDQTPPTQAGGGNGGGRFNQPNAGQTQTVPQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLI
GEPGVGKTAVVEGLAQKIVDGDVPHKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREVILFIDEIHEIVGA
GSAGDGNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQNKYQDYHHVKYS
PEAIEAAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDQRLIDAENRKEQATRDEDYEKAAYYRDQIAKY
KEMQKATISEEDIPLITEKEIEAIIEQKTNIPVGELKEKEQSQLIHLASDLKAHVIGQDDAVDKIAKAIRRNRVGLGAPN
RPIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLIL
LDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLGNFFTPEFM
NRFDGIIEFQPLTKENLLQIVSLMLEDVNRRLSTNGIRLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYL
ENPNEKDLRAVMTNKGTIQIKAQTQKEK

Nucleotide


Download         Length: 2247 bp        

>NTDB_id=626207 LOD77_RS07770 WP_274505301.1 1517727..1519973(+) (clpE) [Streptococcus parasuis strain SS20]
ATGCTCTGTACAAACTGTAAAATAAATGATGCTACCATTCATCTCTATACAAATATGAATGGCAAACAACAGAAAGTTGA
CCTTTGCCATAATTGTTATCAAATTATGAAAACAGATCCAAATAATGCTATCTTACGTGGCTTAGGGGAGAACTTAACTA
ATCCAAACAATATGGATCCCTTTAGTGAATTTTTCAATCATTTAGGTGGTTACCCTGGTAATACCCCAGCTGGTAAGAAT
CGAGATCAAACACCTCCTACTCAAGCAGGCGGTGGCAACGGTGGTGGTCGATTCAATCAACCAAATGCGGGTCAAACCCA
AACAGTCCCACAACCAAATGGATTGCTGGAAGAATTTGGGATTAATGTTACTGAGATTGCACGACGTGGAGATATTGACC
CCGTTATCGGACGCGATCAAGAAATCACTCGGGTGATTGAAATTTTGAACCGTCGCACCAAAAACAACCCTGTTCTTATC
GGTGAGCCCGGTGTTGGTAAAACTGCAGTCGTTGAAGGATTAGCACAAAAAATTGTAGACGGGGACGTTCCACATAAACT
TCAAAACAAAGAAGTCATTCGATTAGACGTTGTCAGCCTTGTTCAAGGAACAGGAATCCGAGGTCAATTTGAAGAACGCA
TGCAAAAACTCATGGAAGAAATTCGGAACCGACGTGAAGTTATTCTCTTCATTGATGAAATTCATGAGATTGTCGGAGCT
GGTTCTGCAGGAGATGGAAACATGGATGCCGGCAATATTCTAAAACCCGCCCTCGCTCGTGGTGAAATGCAACTGGTCGG
TGCTACTACTTTAAATGAATACCGCATTATAGAAAAAGATGCAGCTCTTGAACGTCGGATGCAACCTGTAAAAGTTGACG
AACCAAGCGTTGAAGAAACAATCACTATCTTAAAAGGTATTCAGAATAAATACCAAGACTACCACCATGTAAAATATTCC
CCTGAGGCAATTGAAGCTGCGGCCGTATTATCCAACCGCTATATTCAAGACCGATTCTTACCTGATAAAGCGATTGATTT
GCTAGACGAAGCTGGATCAAAAATGAACTTAACCTTGAACTTCGTGGATCCTAAAGAAATTGACCAACGGTTAATTGATG
CCGAAAATCGTAAAGAACAAGCAACTCGTGATGAAGATTACGAAAAAGCCGCCTATTATCGTGACCAAATTGCTAAATAT
AAAGAAATGCAAAAGGCAACGATTAGTGAGGAGGATATTCCTCTCATTACCGAAAAAGAAATCGAAGCCATCATTGAACA
AAAAACAAATATCCCCGTTGGCGAGCTGAAAGAAAAAGAACAGTCTCAATTGATACATTTGGCAAGTGATCTCAAAGCGC
ATGTCATTGGACAAGACGATGCTGTTGATAAGATTGCAAAAGCAATCCGTCGCAATCGTGTAGGACTTGGAGCACCAAAT
CGTCCAATTGGTTCCTTCTTATTCGTAGGACCTACTGGCGTCGGTAAAACAGAATTATCAAAACAATTAGCCATTGAGCT
CTTCGGTTCAGCGGACAGCATGATTCGATTTGATATGTCTGAATATATGGAAAAACACGCAGTTGCAAAACTAGTCGGTG
CCCCTCCTGGATATGTGGGGTATGAAGAAGCTGGCCAACTAACAGAAAAAGTCCGTCGCAATCCGTACTCACTCATTCTC
CTTGATGAAGTTGAAAAGGCGCATCCAGATGTGATGCATATGTTTCTACAAGTTCTTGATGACGGTCGACTGACAGATGG
ACAAGGGCGAACAGTCAGCTTCAAAGATACCATTATCATTATGACTTCAAATGCTGGTACAGGTAAGGTTGAGGCCAGCG
TGGGATTTGGAGCCGCTATGGAAGGTCGTACACAATCTGTTCTTGGCCAACTCGGTAATTTCTTCACTCCCGAATTCATG
AACCGCTTCGATGGAATTATTGAATTCCAACCACTTACAAAAGAGAATCTGCTCCAAATTGTCAGTCTCATGCTGGAAGA
CGTCAACCGTCGCTTATCTACAAACGGTATTCGACTACATGTGACCGATAAAGTAAAGGAAAAATTAGTTGATCTTGGTT
ACGATCCTAAAATGGGTGCACGTCCCCTTCGCAGGACCATTCAAGACCAAATTGAAGATGCCATTACCGATTTCTATTTA
GAGAATCCTAATGAGAAAGATTTACGAGCTGTCATGACCAATAAAGGCACCATCCAAATCAAAGCTCAAACGCAAAAAGA
AAAATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(481-644)

ATPase family associated with various cellular activities (AAA) (AAA)

(158-277)

AAA lid domain (AAA_lid_9)

(296-394)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(652-724)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

82.713

100

0.832
  clpE Streptococcus pneumoniae D39

82.713

100

0.832
  clpE Streptococcus pneumoniae R6

82.713

100

0.832
  clpE Streptococcus pneumoniae TIGR4

82.713

100

0.832
  clpE Streptococcus mutans UA159

82.667

100

0.829
  clpC Lactococcus lactis subsp. cremoris KW2

75.469

99.733

0.753
  clpC Bacillus subtilis subsp. subtilis str. 168

51.008

86.23

0.44
  clpC Streptococcus mutans UA159

47.91

83.155

0.398
  clpC Streptococcus pneumoniae TIGR4

47.444

83.69

0.397
  clpC Streptococcus pneumoniae Rx1

47.444

83.69

0.397
  clpC Streptococcus pneumoniae D39

47.444

83.69

0.397
  clpC Streptococcus thermophilus LMD-9

47.125

83.69

0.394
  clpC Streptococcus thermophilus LMG 18311

46.805

83.69

0.392
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.85

82.754

0.388