Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   LOD77_RS03185 Genome accession   NZ_CP086728
Coordinates   619304..620008 (+) Length   234 a.a.
NCBI ID   WP_174845892.1    Uniprot ID   -
Organism   Streptococcus parasuis strain SS20     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 614304..625008
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LOD77_RS03165 (LOD77_03155) - 616100..616759 (-) 660 WP_274505713.1 amino acid ABC transporter permease -
  LOD77_RS03170 (LOD77_03160) - 616774..617472 (-) 699 WP_172036401.1 amino acid ABC transporter permease -
  LOD77_RS03175 (LOD77_03165) - 617487..618326 (-) 840 WP_274505714.1 transporter substrate-binding domain-containing protein -
  LOD77_RS03180 (LOD77_03170) - 618336..619097 (-) 762 WP_274505715.1 amino acid ABC transporter ATP-binding protein -
  LOD77_RS03185 (LOD77_03175) micA 619304..620008 (+) 705 WP_174845892.1 response regulator YycF Regulator
  LOD77_RS03190 (LOD77_03180) micB 620001..621350 (+) 1350 WP_274505716.1 cell wall metabolism sensor histidine kinase VicK Regulator
  LOD77_RS03195 (LOD77_03185) vicX 621357..622160 (+) 804 WP_171988530.1 MBL fold metallo-hydrolase Regulator
  LOD77_RS03200 (LOD77_03190) pbp2b 622439..624511 (+) 2073 WP_274505717.1 penicillin-binding protein PBP2B -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26799.79 Da        Isoelectric Point: 4.7428

>NTDB_id=626191 LOD77_RS03185 WP_174845892.1 619304..620008(+) (micA) [Streptococcus parasuis strain SS20]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALDIFEAEFPDIVILDLMLPEIDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQEAVESSGTPELVIGDLVIVPDAFVAKKHGKELELT
HREFELLYHLAKHIGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYFIKAYD

Nucleotide


Download         Length: 705 bp        

>NTDB_id=626191 LOD77_RS03185 WP_174845892.1 619304..620008(+) (micA) [Streptococcus parasuis strain SS20]
ATGAAGAAAATTTTAATTGTTGATGATGAGAAACCAATCTCGGATATTATTAAGTTCAATATGACACGTGAAGGATATGA
GGTAGTTACTGCGTTTGATGGACGTGAGGCGCTTGATATTTTTGAAGCAGAGTTTCCAGACATTGTTATTTTAGATTTAA
TGCTTCCAGAAATAGATGGATTAGAAGTAGCACGGACGATTCGAAAAACAAGTAATGTTCCTATTTTAATGTTGTCAGCT
AAAGATAGTGAGTTTGATAAAGTTATTGGGCTTGAAATTGGTGCGGATGACTATGTGACAAAGCCATTCTCAAACCGTGA
ATTACAGGCGCGTGTAAAAGCTCTTCTTCGTCGAAGTGAATTGGCTGAGACGCAAGAAGCAGTTGAATCATCTGGTACTC
CAGAATTGGTAATCGGTGATTTGGTAATTGTTCCAGATGCTTTTGTAGCTAAGAAACATGGAAAAGAACTTGAACTAACA
CACCGTGAATTTGAATTATTGTATCATTTGGCCAAGCACATTGGACAAGTCATGACGCGAGAGCATCTACTTGAGACTGT
TTGGGGATATGATTATTTTGGAGATGTACGTACTGTGGACGTGACGGTTCGACGCTTGCGTGAAAAAATTGAAGACACTC
CAAGTCGTCCGGAATATATCTTGACACGCAGGGGAGTAGGTTATTTTATAAAAGCTTATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

83.983

98.718

0.829
  vicR Streptococcus mutans UA159

80.851

100

0.812
  covR Streptococcus salivarius strain HSISS4

43.29

98.718

0.427
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.478

98.291

0.427
  scnR Streptococcus mutans UA159

36.709

100

0.372