Detailed information NTG0626181

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: LOD77_RS01050
• Genome accession: NZ_CP086728
• Coordinates: 195422..197875 (+)
• Length: 817 a.a.
• NCBI ID: WP_274505541.1
• Uniprot ID: -
• Organism: Streptococcus parasuis strain SS20
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 190422..202875

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LOD77_RS01025 (LOD77_01010)	-	191160..192143 (+)	984	WP_216806175.1	DUF4767 domain-containing protein	-
LOD77_RS01030 (LOD77_01015)	rpsB	192343..193119 (+)	777	WP_171989595.1	30S ribosomal protein S2	-
LOD77_RS01035 (LOD77_01020)	tsf	193275..194315 (+)	1041	WP_174846563.1	translation elongation factor Ts	-
LOD77_RS01040 (LOD77_01025)	-	194476..194814 (-)	339	WP_174846564.1	thioredoxin domain-containing protein	-
LOD77_RS01045 (LOD77_01030)	-	194958..195416 (+)	459	WP_171989598.1	CtsR family transcriptional regulator	-
LOD77_RS01050 (LOD77_01035)	clpC	195422..197875 (+)	2454	WP_274505541.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
LOD77_RS01055 (LOD77_01040)	-	198469..198852 (+)	384	WP_274505542.1	hypothetical protein	-
LOD77_RS01060 (LOD77_01045)	-	198872..199105 (+)	234	WP_024396363.1	hypothetical protein	-
LOD77_RS01065 (LOD77_01050)	-	199102..199344 (+)	243	WP_274505543.1	hypothetical protein	-
LOD77_RS01070 (LOD77_01055)	-	199505..200761 (+)	1257	WP_274505544.1	ISL3 family transposase	-
LOD77_RS01075 (LOD77_01060)	dusB	200894..201898 (-)	1005	WP_172024665.1	tRNA dihydrouridine synthase DusB	-
LOD77_RS01080 (LOD77_01065)	hslO	201891..202757 (-)	867	WP_274505545.1	Hsp33 family molecular chaperone HslO	-

Sequence

Protein

• Length: 817 a.a.
• Molecular weight: 90488.90 Da
• Isoelectric Point: 5.7872

>NTDB_id=626181 LOD77_RS01050 WP_274505541.1 195422..197875(+) (clpC) [Streptococcus parasuis strain SS20]
MKFSTGLQRVFEDAQLIAQRYACDHLETWHILLAFVINHDTVAGAVLAEYPMSISDFEHATFVVTEKVYREELDKFNVLS
SSKRLEDTAQFARKIAEVVKAKELGSEHLFQAMLLDKRSTASQILDKVGFHFEEIEDEFRFVDLRKNLEYRAGFTKEDLK
AIRSVMKGGKAKTASVGQMMGMPPTAQSGGLEDYTRDLTALAREGKIEPVIGRDAEISRMIQILSRKTKNNPVLVGDAGV
GKTALALGLAQRVAEGDVPVSLAKMRVLELDLMNVIAGTRFRGDFEERMNNIINDIEEDGQVILFIDELHTIMGSGSGID
STLDAANILKPALARGTLRTVGATTQDEYQKHIEKDAALVRRFAKVTIEEPTVEDSIAILTGLKGTFEKYHRVRIGDAAV
ETAVAYAKRYLTSKNLPDSAIDLLDEASATVQNRVKGQVEETGLSTIDKALMAGKYKTVSKLLIKTTEKNLLSQNDDLEV
TEDDILETLSRLSGIPVAKLSQSDTKKYLNLEAELHKRVIGQEEAISAVSRAIRRNQSGIRTGRRPIGSFMFLGPTGVGK
TELAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLL
QVLDDGVLTDSKGRKVDFSNTVIIMTSNLGATALRDDKTVGFGAADLSKDHKEVEKRIFEELKKTYRPEFINRIDEKVVF
HSLTESDMLDVVKVMVKPLIVVAASKGILLKFQPSALKLLAKEGYDPEMGARPLRRLLQTKLEDPMAEMLLRGDLTTGST
LKVGVKGEELKFDVVKG

Nucleotide

• Length: 2454 bp

>NTDB_id=626181 LOD77_RS01050 WP_274505541.1 195422..197875(+) (clpC) [Streptococcus parasuis strain SS20]
ATGAAATTTTCAACAGGCTTACAACGGGTTTTTGAAGATGCTCAGTTGATTGCCCAACGATATGCATGCGATCATTTAGA
AACGTGGCATATTTTGCTAGCATTTGTCATCAATCACGATACGGTAGCTGGTGCTGTTTTGGCAGAATACCCAATGAGTA
TTTCAGATTTCGAACATGCTACTTTTGTTGTTACAGAAAAAGTATACCGTGAAGAATTGGATAAATTTAATGTTCTATCC
TCCTCAAAAAGATTAGAGGATACAGCTCAGTTCGCTAGAAAGATTGCAGAAGTCGTTAAGGCAAAAGAATTAGGAAGCGA
GCATTTGTTTCAGGCAATGCTGTTAGACAAACGTTCAACCGCAAGTCAAATTCTAGATAAAGTAGGTTTTCATTTTGAAG
AGATAGAAGATGAATTCCGTTTTGTTGATTTGCGTAAAAACTTAGAGTATCGTGCAGGGTTCACCAAAGAGGATTTGAAA
GCTATCCGTAGCGTGATGAAAGGTGGAAAGGCTAAAACAGCAAGTGTAGGTCAAATGATGGGCATGCCACCAACTGCTCA
AAGTGGTGGATTGGAGGATTATACACGAGATCTGACAGCCTTAGCCCGCGAGGGTAAAATTGAACCTGTTATTGGTCGCG
ATGCTGAAATTTCACGGATGATTCAAATTCTATCACGTAAAACGAAGAACAATCCTGTTTTGGTTGGCGATGCAGGTGTT
GGGAAAACAGCACTAGCATTAGGTCTTGCTCAGCGTGTTGCAGAAGGAGATGTTCCTGTCAGTTTAGCAAAGATGCGTGT
TTTGGAACTTGATTTAATGAATGTTATTGCAGGAACTCGTTTCCGTGGTGACTTTGAAGAGCGGATGAATAATATCATCA
ATGATATTGAAGAAGATGGTCAGGTTATCCTCTTTATCGATGAATTACATACTATTATGGGGTCGGGTTCGGGAATTGAT
TCAACCTTAGATGCTGCCAATATTCTCAAACCGGCCTTGGCTCGAGGGACCCTACGCACTGTTGGTGCAACGACACAGGA
TGAATACCAAAAGCATATTGAAAAAGATGCTGCCCTGGTCCGTCGTTTTGCCAAAGTGACCATTGAAGAGCCGACAGTTG
AGGACAGTATTGCCATTTTGACCGGGCTTAAAGGGACTTTTGAAAAATACCATAGGGTCCGTATTGGAGATGCGGCTGTT
GAGACAGCTGTGGCTTACGCCAAGAGGTATCTGACTAGTAAAAACTTGCCAGACTCAGCAATTGACTTGTTAGATGAAGC
CAGTGCAACTGTACAAAATAGAGTGAAAGGGCAGGTTGAAGAAACAGGTCTTTCGACTATTGATAAAGCTTTGATGGCTG
GAAAATACAAGACTGTCAGTAAGCTCTTAATCAAGACTACAGAAAAGAATCTGTTGAGTCAAAACGATGACTTAGAAGTG
ACAGAAGATGACATTTTGGAAACACTTAGTCGCTTATCAGGTATCCCAGTAGCCAAGCTCAGCCAATCAGATACTAAGAA
ATACCTGAATCTGGAAGCAGAATTGCACAAACGTGTGATTGGGCAGGAAGAAGCTATTTCTGCCGTTAGTAGAGCTATCC
GCCGTAATCAGTCGGGGATTCGGACAGGTCGCAGACCGATTGGTTCCTTTATGTTCTTAGGACCAACTGGTGTCGGTAAG
ACTGAGCTTGCTAAAGCCTTGGCAGAGGTTCTCTTTGATGATGAATCTGCTCTTATCCGTTTTGATATGTCTGAGTATAT
GGAGAAATTTGCGGCCAGCCGTCTCAATGGAGCGCCTCCAGGCTATGTTGGCTATGAAGAAGGTGGCGAATTAACAGAAA
AAGTTCGTAATAAACCTTATTCTGTTCTTCTTTTTGATGAGGTTGAAAAGGCTCATCCAGATATTTTCAATGTTCTCTTG
CAGGTCTTGGATGACGGTGTCTTGACCGATAGTAAGGGTCGCAAGGTTGATTTCTCCAATACAGTCATTATCATGACATC
AAACTTGGGAGCAACAGCTCTTCGCGATGACAAGACCGTTGGGTTTGGTGCGGCTGATCTGTCCAAAGACCACAAGGAAG
TGGAGAAACGCATTTTTGAAGAATTGAAAAAGACCTATCGTCCTGAATTTATCAACCGTATCGATGAAAAGGTAGTCTTC
CACAGCTTGACAGAATCCGATATGTTGGATGTTGTCAAAGTGATGGTGAAGCCATTGATTGTGGTTGCCGCGAGCAAGGG
AATCCTCCTGAAATTCCAACCATCAGCCCTCAAATTGTTGGCCAAAGAAGGCTACGATCCAGAAATGGGTGCTCGCCCTC
TTCGTCGGTTGCTCCAAACAAAATTGGAAGACCCGATGGCAGAAATGTTGCTCCGTGGTGACCTGACTACTGGTTCGACC
TTGAAGGTTGGGGTCAAGGGCGAAGAGCTCAAGTTTGATGTGGTAAAGGGTTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

• AAA lid domain (AAA_lid_9) (372-449)

• ATPase family associated with various cellular activities (AAA) (AAA) (233-365)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (102-137)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-49)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae TIGR4	71.043	99.755	0.709
clpC	Streptococcus pneumoniae D39	71.043	99.755	0.709
clpC	Streptococcus pneumoniae Rx1	71.043	99.755	0.709
clpC	Streptococcus mutans UA159	66.258	99.755	0.661
clpC	Streptococcus thermophilus LMG 18311	65.606	100	0.656
clpC	Streptococcus thermophilus LMD-9	65.606	100	0.656
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.795	100	0.496
clpC	Bacillus subtilis subsp. subtilis str. 168	42.891	100	0.443