Detailed information NTG0626014

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: LN243_RS05225
• Genome accession: NZ_CP086659
• Coordinates: 1070937..1071983 (+)
• Length: 348 a.a.
• NCBI ID: WP_002435929.1
• Uniprot ID: A0A0S4MEI3
• Organism: Staphylococcus capitis strain XZ03
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1065937..1076983

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LN243_RS05195	-	1066201..1066926 (+)	726	WP_002469718.1	type 1 glutamine amidotransferase	-
LN243_RS05200	isaB	1067155..1067697 (+)	543	WP_023350030.1	immunodominant staphylococcal antigen IsaB family protein	-
LN243_RS05205	-	1067775..1068764 (-)	990	WP_002435886.1	FUSC family protein	-
LN243_RS05210	map	1068938..1069693 (+)	756	WP_002435911.1	type I methionyl aminopeptidase	-
LN243_RS05215	-	1069838..1070224 (+)	387	WP_002453601.1	hypothetical protein	-
LN243_RS05220	liaF	1070239..1070940 (+)	702	WP_002435891.1	cell wall-active antibiotics response protein LiaF	-
LN243_RS05225	vraS	1070937..1071983 (+)	1047	WP_002435929.1	sensor histidine kinase	Regulator
LN243_RS05230	vraR	1071973..1072602 (+)	630	WP_002469716.1	two-component system response regulator VraR	Regulator
LN243_RS05235	-	1072667..1073920 (-)	1254	WP_002435884.1	YihY/virulence factor BrkB family protein	-
LN243_RS05240	-	1074257..1074541 (-)	285	WP_002435890.1	hypothetical protein	-
LN243_RS05245	-	1074548..1075012 (-)	465	WP_002435947.1	low molecular weight protein-tyrosine-phosphatase	-
LN243_RS05250	-	1075153..1075359 (+)	207	WP_002435959.1	DUF1128 domain-containing protein	-
LN243_RS05255	-	1075373..1076614 (+)	1242	WP_023350031.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40136.57 Da
• Isoelectric Point: 6.0600

>NTDB_id=626014 LN243_RS05225 WP_002435929.1 1070937..1071983(+) (vraS) [Staphylococcus capitis strain XZ03]
MNHYLRAIGSMLILVYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNILIILLCIIVGSVLAYKINQQNDWLKS
QIERSIEGETVGINDQNLELYSETLEIYHTLVPLNQELHRLRMKTQNMTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGSKVTVELFNKEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDESNGD

Nucleotide

• Length: 1047 bp

>NTDB_id=626014 LN243_RS05225 WP_002435929.1 1070937..1071983(+) (vraS) [Staphylococcus capitis strain XZ03]
ATGAATCACTACTTGAGAGCAATTGGTTCAATGCTAATACTTGTATATAGCATGCTAACTGCTTTTTTATTCATTGATAA
GGTGTTCGTCAATATTATTTATTTTCAAGGGATGTTTTACACCCAAATTTTTGGAATACCAGTATTTTTATTCCTAAATA
TATTAATCATCTTACTATGTATTATCGTTGGCTCTGTGTTAGCGTATAAAATCAATCAACAAAATGATTGGCTTAAGTCA
CAAATTGAAAGGTCTATTGAAGGTGAAACAGTAGGCATAAATGATCAAAACCTAGAGTTATACAGTGAAACGTTAGAAAT
TTACCATACTTTAGTTCCTTTAAATCAAGAATTACACCGATTGAGAATGAAAACGCAGAATATGACCAATGAAAATTATA
ATATGAATGATGTAAAAGTGAAGAAAATTATTGAAGACGAACGTCAACGTTTAGCAAGAGAACTACATGACTCAGTTAGT
CAGCAACTATTTGCAGCAAGTATGATGTTGTCAGCGATTAAAGAGTCAAAATTAGAACCACCTTTAGACCAACAAATACC
TGTACTAGAGAAGATGGTTCAAGACTCTCAGCTCGAAATGAGAGCATTATTATTACATCTAAGACCTATTGGTTTGAAAG
ACAAATCATTAGGAGAGGGTATTAAAGATTTAGTCATTGATCTTCAAAAGAAAGTCCCTATGAAAGTTGTTCATGAAATT
CAAGATTTCAAAGTACCAAAAGGGATAGAAGATCATTTGTTTAGAATCACCCAAGAGGCTATTTCTAATACATTACGACA
CTCTAATGGTTCTAAGGTAACAGTTGAATTATTTAATAAAGAAGATTATTTACTACTTAGAATTCAAGATAATGGTAAAG
GTTTTAATGTAGATGAAAAATTTGAACAGAGTTATGGATTAAAAAATATGAGAGAACGTGCTTTAGAGATTGGTGCCACA
TTCCATATCGTATCGTTACCGGATTCAGGTACGAGAATAGAAGTTAAAGCACCATTGAATAAGGAGGATGAATCAAATGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A0S4MEI3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.586	98.563	0.922