Detailed information NTG0625597

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: LK342_RS09135
• Genome accession: NZ_CP086574
• Coordinates: 1925256..1926299 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus argenteus strain RIVM_M046968
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1920256..1931299

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LK342_RS09105 (LK342_09105)	-	1920667..1921914 (-)	1248	WP_000656301.1	aminopeptidase	-
LK342_RS09110 (LK342_09110)	-	1921926..1922126 (-)	201	WP_000180459.1	DUF1128 family protein	-
LK342_RS09115 (LK342_09115)	-	1922273..1922737 (+)	465	WP_000228669.1	low molecular weight protein-tyrosine-phosphatase	-
LK342_RS09120 (LK342_09120)	-	1922744..1923019 (+)	276	WP_000428174.1	YtxH domain-containing protein	-
LK342_RS09125 (LK342_09125)	-	1923298..1924521 (+)	1224	WP_000037065.1	YihY/virulence factor BrkB family protein	-
LK342_RS09130 (LK342_09130)	vraR	1924637..1925266 (-)	630	WP_000153529.1	two-component system response regulator VraR	Regulator
LK342_RS09135 (LK342_09135)	vraS	1925256..1926299 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
LK342_RS09140 (LK342_09140)	liaF	1926296..1926997 (-)	702	WP_047528366.1	cell wall-active antibiotics response protein LiaF	-
LK342_RS09145 (LK342_09145)	-	1927012..1927398 (-)	387	WP_047528367.1	hypothetical protein	-
LK342_RS09150 (LK342_09150)	map	1927652..1928410 (-)	759	WP_031788218.1	type I methionyl aminopeptidase	-
LK342_RS09155 (LK342_09155)	-	1928934..1929920 (+)	987	WP_047557232.1	aromatic acid exporter family protein	-
LK342_RS09160 (LK342_09160)	-	1930322..1930702 (-)	381	WP_225995313.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=625597 LK342_RS09135 WP_001017131.1 1925256..1926299(-) (vraS) [Staphylococcus argenteus strain RIVM_M046968]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=625597 LK342_RS09135 WP_001017131.1 1925256..1926299(-) (vraS) [Staphylococcus argenteus strain RIVM_M046968]
ATGAACCATTATATTAGAACAATTGGTTCGATGCTCATCTTAGTATACAGCATGCTAGCGGCATTTCTTTTTATAGATAA
AGTTTTCGTTAATATTATTTATTTTCAAGGCATGTTTTATACACAAATATTTGGGATTCCAGTCTTTTTATTTTTAAATC
TCATTATCATTTTATTGTGTATCATCGTTGGATCGGTGCTTGCCTACAAAATTAATCAACAAAATGACTGGATTAAGACA
CAAATTGAGCGTTCTATGGAAGGCGAAACAGTAGGTATCAATGATCAAAATATAGAAATATATAGTGAAACATTAGATTT
ATATCATACGTTAGTACCTTTAAATCAAGAATTGCATAAGTTAAGACTCAAAACGCAAAATTTAACAAATGAAAATTACA
ATATTAATGATGTTAAAGTTAAAAAGATTATCGAAGATGAAAGACAACGTTTAGCTAGAGAACTACACGACTCTGTTAGT
CAACAACTTTTTGCGGCAAGTATGATGTTATCTGCAATTAAAGAAACAAAATTAGAACCACCTTTAGATCAACAAATACC
TATTTTAGAGAAAATGGTTCAAGATTCTCAGTTAGAAATGCGTGCTCTGCTGCTACACTTAAGACCACTCGGCTTGAAAG
ATAAGTCATTAGGCGAAGGTATTAAAGATTTAGTTATTGATTTACAAAAGAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCAAAAGGTATTGAGGATCATTTATTTAGAATTACGCAAGAAGCAATATCTAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTAGAATTATTTAATAAAGATGATTATTTATTGTTAAGGATACAAGATAATGGTAAAG
GTTTTAATGTAGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCACTACCAGATTCAGGTACACGTATTGAGGTGAAAGCACCTCTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1