Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   FNL60_RS09960 Genome accession   NZ_AP019720
Coordinates   1946175..1948130 (-) Length   651 a.a.
NCBI ID   WP_002280015.1    Uniprot ID   -
Organism   Streptococcus mutans strain NBRC 13955     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1941175..1953130
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FNL60_RS09935 (SM3g_18340) spx 1941679..1942077 (-) 399 WP_002262391.1 transcriptional regulator Spx -
  FNL60_RS09940 (SM3g_18350) recA 1942162..1943313 (-) 1152 WP_002262392.1 recombinase RecA Machinery gene
  FNL60_RS09945 (SM3g_18360) cinA 1943353..1944609 (-) 1257 WP_002280016.1 competence/damage-inducible protein A Machinery gene
  FNL60_RS09950 (SM3g_18370) - 1944758..1945318 (-) 561 WP_002266114.1 DNA-3-methyladenine glycosylase I -
  FNL60_RS09955 (SM3g_18380) ruvA 1945400..1945993 (-) 594 WP_002266975.1 Holliday junction branch migration protein RuvA Machinery gene
  FNL60_RS09960 (SM3g_18390) hexB 1946175..1948130 (-) 1956 WP_002280015.1 DNA mismatch repair endonuclease MutL Machinery gene
  FNL60_RS09965 - 1948356..1948634 (+) 279 Protein_1860 transposase -
  FNL60_RS09970 (SM3g_18400) hexA 1948629..1951178 (-) 2550 WP_002268464.1 DNA mismatch repair protein MutS Machinery gene
  FNL60_RS09975 (SM3g_18410) - 1951171..1951518 (-) 348 WP_002264540.1 YlbF family regulator -
  FNL60_RS09980 (SM3g_18420) argR 1951515..1951952 (-) 438 WP_002262400.1 arginine repressor -
  FNL60_RS09985 (SM3g_18430) - 1952349..1952804 (-) 456 WP_226705521.1 Crp/Fnr family transcriptional regulator -

Sequence

Protein


Download         Length: 651 a.a.        Molecular weight: 73813.49 Da        Isoelectric Point: 6.4597

>NTDB_id=62543 FNL60_RS09960 WP_002280015.1 1946175..1948130(-) (hexB) [Streptococcus mutans strain NBRC 13955]
MSKIIELPEVLANQIAAGEVIERPASVVKELVENAIDADSSQITIEIEESGLKKIQVTDNGQGIEQADVIMSLRRHATSK
IKKQSDLFRIRTLGFRGEALPSIASISRLTLKTATKGEIYGTLLIANGGKIEKEEAISTPIGTKVSVENLFFNTPARLKY
MKSLQAELAHIIDVINRLSLAHPEIAFTLINDGRELTKTSGKGDLRQALAGIYGVTTAKKMVEISNADLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMNLISS
AIADSLREQELIPDALENLAKTSTNKKQKFEQTQLPLKQSNLYYDKTQNDFFLKETTVSEASSEFTVVDKAVNITDNVSG
HSSVKYAQRQMRTCENKEHPSLTMTNKQQKRQLSRIVESLENEEKSTFPELEYFGQMHGTYLFAQGEGGLYIIDQHAAQE
RVKYEYYRDKIGEVDNSLQQLLVPYLFEFPANDFMTLQEKMSILNEVGVHLENYGENTFILREHPIWLQEKEIESAVYEM
CDMLLLTNEVSIKKYRAELAIMMSCKRSIKANHTLDDYSARNLLIQLSQCKNPYNCPHGRPVLVNFTKADMEKMFRRIQE
NHTSLRELGKY

Nucleotide


Download         Length: 1956 bp        

>NTDB_id=62543 FNL60_RS09960 WP_002280015.1 1946175..1948130(-) (hexB) [Streptococcus mutans strain NBRC 13955]
ATGTCAAAAATTATTGAACTGCCAGAAGTTTTAGCCAATCAAATTGCTGCTGGAGAGGTTATTGAAAGACCAGCTAGTGT
CGTAAAAGAACTAGTTGAGAATGCTATTGACGCTGATAGCAGCCAAATTACAATAGAAATTGAAGAATCAGGACTGAAAA
AAATTCAAGTGACTGATAATGGTCAAGGAATAGAACAAGCGGATGTAATTATGAGCTTACGTCGTCATGCAACTAGTAAG
ATTAAAAAACAATCCGATCTTTTTAGAATTAGGACCTTAGGTTTTAGAGGTGAGGCCCTTCCATCAATTGCTTCTATTAG
CAGACTAACATTAAAAACAGCAACAAAAGGGGAAATATATGGCACTTTATTAATCGCAAATGGAGGTAAAATTGAAAAAG
AAGAAGCCATTAGTACCCCTATTGGAACCAAAGTGAGTGTTGAAAATCTTTTCTTCAATACCCCTGCTCGCCTTAAATAT
ATGAAAAGTTTGCAGGCAGAGCTTGCTCATATTATTGATGTCATTAACCGTCTTAGCTTGGCGCATCCCGAAATTGCTTT
CACGCTTATTAATGATGGCCGTGAATTAACAAAGACGTCAGGTAAAGGCGATCTGCGTCAAGCTTTAGCGGGTATTTATG
GGGTAACCACTGCTAAAAAAATGGTCGAAATTTCAAATGCAGATCTTGATTTTGAGGTATCTGGTTATATTAGTTTGCCT
GAATTAACACGAGCTAATCGCAATTATATTACCATTCTTATTAATGGGCGTTATATCAAAAATTTTTTGCTCAATCGCGC
TATTCTTGATGGTTATGGTTCAAAATTAATGGTGGGACGTTTTCCAATTGCTGTTATTGATATTCAGATTGACCCTTATT
TAGCAGATGTTAATGTTCATCCAACTAAGCAGGAAGTTCGCATTTCTAAAGAAAAAGAGTTAATGAATCTCATTAGTTCG
GCAATTGCAGATAGTTTAAGAGAACAAGAGTTAATTCCTGATGCTTTGGAAAATCTTGCTAAAACTAGCACAAACAAGAA
ACAAAAGTTTGAACAAACACAACTTCCTCTTAAACAATCAAATCTTTACTATGATAAGACTCAAAATGACTTCTTTCTCA
AAGAAACGACAGTTTCAGAAGCATCAAGCGAGTTTACAGTAGTTGATAAAGCTGTAAATATTACTGATAATGTATCAGGA
CATAGCAGTGTAAAATATGCTCAACGTCAAATGAGAACTTGTGAAAACAAAGAGCATCCAAGTCTTACTATGACAAATAA
GCAACAAAAGCGACAGCTTAGTAGAATTGTTGAAAGTCTAGAAAATGAAGAAAAGTCAACTTTTCCTGAGTTAGAATATT
TTGGTCAAATGCATGGAACTTACCTCTTTGCTCAAGGTGAAGGGGGGCTTTATATCATAGATCAACATGCTGCTCAAGAA
CGTGTTAAATATGAATATTATCGTGATAAAATTGGAGAAGTAGACAATAGTTTACAGCAGCTTTTAGTACCTTATCTTTT
TGAATTTCCTGCTAATGATTTTATGACCTTACAAGAAAAAATGAGCATTTTAAATGAGGTTGGAGTTCACTTAGAAAACT
ATGGAGAGAATACTTTCATTTTGAGAGAACATCCTATTTGGTTACAGGAAAAAGAAATTGAATCAGCCGTTTATGAGATG
TGTGACATGTTGCTGTTGACAAATGAAGTCTCCATTAAGAAATATCGAGCGGAATTAGCTATTATGATGTCTTGCAAGCG
TTCTATCAAGGCTAATCATACTTTGGATGATTATTCTGCCAGAAATCTCTTAATTCAATTATCACAGTGCAAAAATCCTT
ACAACTGTCCTCATGGACGTCCTGTGCTTGTGAATTTCACAAAAGCTGATATGGAAAAGATGTTTCGTCGCATTCAGGAA
AACCATACTAGTTTGAGAGAATTAGGGAAATACTGA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-136)

MutL C terminal dimerisation domain (MutL_C)

(453-595)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

70.061

100

0.708

Multiple sequence alignment