Detailed information NTG0062500

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: N288_RS07885
• Genome accession: NC_022524
• Coordinates: 1550832..1552958 (-)
• Length: 708 a.a.
• NCBI ID: WP_009794274.1
• Uniprot ID: U5LAG6
• Organism: Bacillus infantis NRRL B-14911
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1545832..1557958

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
N288_RS07870 (N288_08450)	-	1546582..1547022 (+)	441	WP_009794271.1	MarR family winged helix-turn-helix transcriptional regulator	-
N288_RS07875 (N288_08455)	-	1547133..1548827 (+)	1695	WP_009794272.1	M3 family oligoendopeptidase	-
N288_RS07880 (N288_08460)	-	1549097..1550686 (-)	1590	WP_009794273.1	two-component system sensor histidine kinase NtrB	-
N288_RS07885 (N288_08465)	clpC	1550832..1552958 (-)	2127	WP_009794274.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
N288_RS07890 (N288_08470)	-	1553144..1554187 (+)	1044	WP_009794275.1	membrane protein	-
N288_RS07895 (N288_08475)	-	1554229..1554924 (-)	696	WP_022543651.1	hypothetical protein	-
N288_RS07900 (N288_08480)	-	1555010..1555621 (-)	612	WP_009794277.1	CPBP family intramembrane glutamic endopeptidase	-
N288_RS07905 (N288_08485)	-	1555830..1556498 (+)	669	WP_009794278.1	NAD(P)H-binding protein	-
N288_RS07910 (N288_08490)	-	1556563..1556751 (-)	189	WP_009794279.1	YkvS family protein	-
N288_RS07915 (N288_08495)	-	1556972..1557166 (+)	195	WP_022543652.1	hypothetical protein	-

Sequence

Protein

• Length: 708 a.a.
• Molecular weight: 78805.02 Da
• Isoelectric Point: 5.3868

>NTDB_id=62500 N288_RS07885 WP_009794274.1 1550832..1552958(-) (clpC) [Bacillus infantis NRRL B-14911]
MNCEKCQQNQATIQLRFNINGNKIETHLCSSCYQTEKQKMNASFGYQNPFEASGMEDLFKQMGAGEASAGKGMKQQPGKK
PNGFIEQFGKNLSNAANAGLIDPVIGRDEEIDRVIEILNRRNKNNPVLIGEPGVGKTAIAEGLALKISEKKAPRKLLNKE
VYLLDVASLVANTGIRGQFEERMKQLITELQERKNIILFIDEIHLLVGAGSAEGSMDAGNILKPALARGELQVIGATTLK
EYRQIEKDPALERRFQPVHIQEPTQEQALEILKGLQSKYEDFHEVTYSEEALSACVTLSSRYIQDRFLPDKAIDLLDEAG
SKINLTAEYTPGEEIEQKLAEISAAKEEVLKKEDYEKAAKLREQEIKLEIALNNDSAKRPVVEAGHIQEIIERKTGIPVG
KIQQDEQSKMKNLEKSLSEKVIGQEEAVKKVAKAVRRSRAGLKSKNRPIGSFLFVGPTGVGKTELTKTLAEELFGSKDSM
IRLDMSEYMEKHSISKIIGSPPGYVGHDEAGQLTEKVRRNPYSIILLDEIEKAHPDVQHMFLQILEDGRLTDSQGRTVSF
KDSVIIMTSNAGAGHREIKVGFGSSEAVKESGILDSLGSFFKPEFLNRFDSIIEFKQLEKDSLLKIVQLMLEELNTALKE
QDMLLTFTDEAVEKLAELGYHPAFGARPLRRAIQEQLEDKIADFILEDPSCTQLHADLLDGNIVVTGK

Nucleotide

• Length: 2127 bp

>NTDB_id=62500 N288_RS07885 WP_009794274.1 1550832..1552958(-) (clpC) [Bacillus infantis NRRL B-14911]
ATGAACTGTGAAAAATGTCAACAAAACCAGGCAACCATCCAATTAAGGTTTAATATAAATGGAAATAAAATAGAAACACA
TCTCTGCAGCAGCTGCTATCAGACCGAAAAGCAAAAAATGAACGCTTCCTTCGGTTACCAGAATCCCTTCGAGGCTTCCG
GCATGGAAGACTTGTTCAAACAAATGGGCGCCGGTGAAGCTAGTGCCGGCAAGGGAATGAAACAGCAGCCAGGCAAAAAG
CCAAACGGCTTTATCGAACAGTTTGGCAAGAACTTGAGCAATGCAGCCAATGCAGGCTTAATAGATCCTGTCATTGGCAG
GGATGAAGAAATTGACCGTGTCATTGAAATACTCAATCGGAGAAATAAAAATAATCCAGTACTGATCGGAGAGCCCGGTG
TCGGGAAAACTGCCATTGCAGAAGGATTGGCACTGAAAATATCTGAAAAGAAAGCACCCCGCAAACTGCTGAATAAAGAA
GTTTATCTTCTTGATGTCGCTTCGCTTGTTGCCAATACCGGCATTCGCGGACAGTTTGAAGAACGGATGAAACAGCTTAT
CACAGAGCTGCAGGAAAGGAAAAATATTATCCTGTTCATTGATGAAATCCATCTTCTTGTCGGAGCAGGATCCGCCGAAG
GCTCCATGGACGCAGGCAACATCCTGAAGCCTGCTCTTGCCCGCGGCGAACTTCAGGTAATCGGTGCGACAACTTTAAAA
GAATATCGCCAGATTGAAAAAGACCCTGCGCTTGAAAGGCGTTTCCAGCCTGTTCACATTCAGGAGCCAACACAGGAACA
AGCCTTAGAAATCCTGAAAGGCCTCCAGTCCAAATATGAGGACTTCCATGAAGTCACCTATTCGGAAGAGGCGCTGTCGG
CATGCGTCACTCTATCAAGCAGATATATACAGGACAGATTTCTTCCGGATAAAGCCATAGATCTGCTGGATGAAGCAGGA
TCAAAAATCAATCTGACAGCAGAATATACACCAGGGGAAGAAATCGAGCAGAAGCTGGCTGAAATATCAGCTGCCAAAGA
AGAAGTCCTGAAGAAAGAAGACTATGAAAAAGCGGCCAAGCTCCGTGAACAGGAAATCAAGCTTGAAATAGCATTGAACA
ATGATTCGGCAAAGAGGCCGGTAGTGGAAGCGGGACATATCCAGGAGATCATTGAAAGAAAGACCGGCATTCCGGTCGGC
AAAATTCAGCAGGATGAACAATCCAAGATGAAGAACCTTGAAAAATCCCTTTCCGAAAAAGTGATCGGCCAGGAAGAAGC
TGTTAAAAAGGTCGCAAAGGCAGTACGCAGAAGCAGAGCTGGATTAAAATCCAAAAACCGCCCAATCGGCTCTTTCTTAT
TTGTCGGACCAACCGGTGTTGGTAAGACCGAACTGACAAAAACACTTGCTGAAGAGCTCTTCGGCTCTAAAGACAGCATG
ATCAGGCTTGATATGAGCGAATATATGGAAAAACACAGCATTTCAAAAATTATCGGTTCCCCTCCGGGATATGTCGGCCA
TGATGAAGCAGGCCAGCTGACTGAGAAGGTGCGGAGGAATCCATACAGCATCATTCTGCTGGATGAGATAGAAAAAGCCC
ACCCTGACGTACAGCATATGTTCCTCCAGATTCTCGAAGACGGCCGCCTGACAGACAGCCAGGGAAGGACCGTCAGCTTT
AAGGATTCTGTTATCATCATGACAAGCAACGCCGGTGCAGGACACAGGGAAATCAAGGTCGGTTTCGGCAGCAGCGAAGC
TGTCAAGGAATCAGGAATTCTTGATTCTCTGGGCAGTTTCTTCAAGCCTGAGTTCCTGAACAGATTCGACAGCATCATAG
AGTTCAAACAGCTTGAAAAAGACAGCCTGCTGAAAATTGTGCAGCTGATGCTGGAAGAGCTGAATACAGCACTCAAAGAA
CAGGATATGCTGCTGACTTTTACTGATGAAGCAGTTGAAAAACTGGCCGAGCTTGGCTATCATCCGGCGTTTGGAGCCCG
TCCGCTTAGAAGGGCAATCCAGGAGCAGCTGGAAGACAAAATTGCGGACTTTATTCTGGAAGATCCATCATGCACACAGC
TGCATGCAGACCTTTTGGATGGAAATATTGTGGTTACTGGAAAATAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (618-689)

• AAA lid domain (AAA_lid_9) (264-364)

• ATPase family associated with various cellular activities (AAA) (AAA) (127-256)

• AAA domain (Cdc48 subfamily) (AAA_2) (447-612)

3D structure

• AlphaFold DB: U5LAG6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	58.776	100	0.61
clpE	Streptococcus mutans UA159	57.588	100	0.6
clpE	Streptococcus pneumoniae Rx1	56.199	100	0.589
clpE	Streptococcus pneumoniae D39	56.199	100	0.589
clpE	Streptococcus pneumoniae R6	56.199	100	0.589
clpE	Streptococcus pneumoniae TIGR4	56.199	100	0.589
clpC	Bacillus subtilis subsp. subtilis str. 168	51.796	94.35	0.489
clpC	Streptococcus pneumoniae Rx1	42.09	100	0.421
clpC	Streptococcus pneumoniae D39	42.09	100	0.421
clpC	Streptococcus thermophilus LMD-9	46.166	90.254	0.417
clpC	Streptococcus thermophilus LMG 18311	46.288	89.407	0.414
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.173	87.429	0.412
clpC	Streptococcus mutans UA159	46.504	86.864	0.404
clpC	Streptococcus pneumoniae TIGR4	44.817	88.559	0.397