Detailed information NTG0624753

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: LMK00_RS09270
• Genome accession: NZ_CP086395
• Coordinates: 1877710..1879956 (-)
• Length: 748 a.a.
• NCBI ID: WP_252175351.1
• Uniprot ID: -
• Organism: Lactococcus formosensis strain I4/6O
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1872710..1884956

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LMK00_RS09245 (LMK00_09245)	fabZ	1873040..1873498 (+)	459	WP_003134189.1	3-hydroxyacyl-ACP dehydratase FabZ	-
LMK00_RS09250 (LMK00_09250)	uvrB	1873524..1875512 (-)	1989	WP_061414792.1	excinuclease ABC subunit UvrB	-
LMK00_RS09255 (LMK00_09255)	-	1875509..1875964 (-)	456	WP_252175350.1	RNA pyrophosphohydrolase	-
LMK00_RS09260 (LMK00_09260)	def	1876069..1876695 (+)	627	WP_017370260.1	peptide deformylase	-
LMK00_RS09265 (LMK00_09265)	yqeK	1877068..1877655 (-)	588	WP_017370259.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
LMK00_RS09270 (LMK00_09270)	clpC	1877710..1879956 (-)	2247	WP_252175351.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
LMK00_RS09275 (LMK00_09275)	rpoD	1880175..1881299 (-)	1125	WP_306723678.1	RNA polymerase sigma factor RpoD	-
LMK00_RS12165	-	1881414..1881572 (-)	159	Protein_1832	translation initiation factor IF-2 N-terminal domain-containing protein	-
LMK00_RS09280 (LMK00_09280)	dnaG	1881593..1883479 (-)	1887	WP_252175352.1	DNA primase	-

Sequence

Protein

• Length: 748 a.a.
• Molecular weight: 83458.41 Da
• Isoelectric Point: 4.7203

>NTDB_id=624753 LMK00_RS09270 WP_252175351.1 1877710..1879956(-) (clpC) [Lactococcus formosensis strain I4/6O]
MLCQNCKINEATIHLYTNVNGQRKQVDLCQNCYQIMKSGGQESLFAGATNISNNDDPFNPFPDIFQALHGNDQGRTMTPP
TQAGGRGPGGPQNPRGSQAPKGLLEEFGVNITDAARRGEIDPVIGRDSEITRVIEILNRRTKNNPVLIGEPGVGKTAVVE
GLAQKIVDGDVPQKLQNKEVIRLDVVSLVQGTGVRGQFEERMQKLMEEIRKRDDVILFIDEIHEIVGAGSAGDGNMDAGN
ILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVDETITILRGIQKRYEDYHHVKYSDEAILAAANLSN
RYIQDRFLPDKAIDLLDEAGSKKNLTLKFVDPEDIKKRIEQAEVQKNEAMQREDFEKAAHFRDQIAKLRELQSHEISDTD
MPNITEKDIEAIVEEKTHIPVGDLKEKEQTQLINLAEDLKEHVIGQDEAIDKISKAVRRSRVGLGKPNRPIGSFLFVGPT
GVGKTELAKQLAYELFGSRDSMIRFDMSEYMEKHSVAKLIGAPPGYVGYEEAGQLTERVRRNPYSLILLDEIEKAHPDVM
HMFLQILDDGRLTDAQGRTVSFKDAIIIMTSNAGTGKVEASVGFGAAREGRTNSVLGELGNFFSPEFMNRFDAIIEFSAL
SKENLLKIVDLMLDEVNTQIAQNDIHLDVTQAVKEKLVDLGYDPKMGARPLRRTIQDNIEDAIADFYIEHPEYKELLADL
VDDKIVIVNKPEEVKDTADTSDNEDEEK

Nucleotide

• Length: 2247 bp

>NTDB_id=624753 LMK00_RS09270 WP_252175351.1 1877710..1879956(-) (clpC) [Lactococcus formosensis strain I4/6O]
ATGCTCTGCCAAAATTGTAAAATAAATGAAGCGACAATTCACCTTTATACGAATGTGAATGGACAACGTAAGCAAGTGGA
TTTATGCCAAAATTGCTATCAAATTATGAAATCAGGAGGTCAAGAAAGTTTGTTTGCTGGGGCGACAAATATTTCTAATA
ATGATGACCCATTTAATCCATTTCCAGATATTTTCCAAGCCTTACATGGTAATGATCAAGGACGGACAATGACACCTCCA
ACACAAGCTGGAGGTCGAGGTCCAGGAGGTCCACAAAACCCTCGTGGAAGTCAAGCACCTAAAGGACTTCTTGAAGAATT
CGGAGTCAACATTACTGATGCTGCACGTCGTGGAGAAATAGATCCTGTTATTGGGCGAGATTCTGAAATTACACGTGTTA
TCGAAATTTTGAATCGTCGAACAAAAAATAATCCTGTTCTTATCGGTGAACCTGGTGTTGGTAAAACAGCAGTTGTTGAA
GGCTTAGCCCAAAAAATAGTTGATGGTGATGTACCACAAAAACTACAAAATAAAGAAGTTATACGTCTCGATGTTGTTAG
CCTTGTCCAAGGTACTGGTGTACGTGGGCAATTTGAAGAGCGTATGCAAAAGCTGATGGAAGAGATTCGTAAACGCGATG
ACGTTATCCTCTTCATTGATGAAATCCATGAAATTGTTGGTGCTGGTTCAGCAGGTGATGGCAATATGGATGCTGGAAAT
ATCCTTAAACCGGCTTTAGCGCGTGGAGAACTACAACTTGTTGGGGCAACAACACTCAATGAATATAGAATTATCGAAAA
AGACGCGGCACTTGAACGTCGGATGCAACCTGTCAAAGTTGATGAACCCTCTGTAGATGAGACCATCACGATTTTACGTG
GGATTCAAAAACGCTATGAAGACTATCATCATGTGAAATATTCAGATGAAGCAATCTTAGCTGCGGCGAATCTCTCGAAC
CGTTATATACAGGACCGTTTCCTTCCCGATAAAGCAATTGACTTACTGGATGAAGCGGGTTCGAAAAAGAATCTCACCCT
CAAATTTGTTGATCCAGAGGATATCAAGAAACGTATTGAGCAAGCAGAAGTACAAAAAAATGAAGCAATGCAACGTGAAG
ATTTTGAGAAAGCAGCCCATTTCCGTGATCAAATCGCTAAGCTTCGGGAGCTTCAAAGTCATGAAATTTCAGATACAGAT
ATGCCAAATATCACAGAAAAAGATATAGAAGCAATCGTTGAAGAAAAAACACATATTCCTGTGGGTGATCTGAAAGAAAA
AGAGCAAACACAGCTGATCAATTTGGCCGAGGACTTGAAAGAACATGTTATTGGACAAGATGAAGCGATTGATAAAATTT
CTAAAGCTGTGCGTCGTTCACGTGTCGGACTTGGAAAACCTAATCGTCCTATCGGTTCATTCCTCTTTGTTGGACCGACT
GGTGTAGGTAAGACTGAACTCGCTAAACAATTAGCTTATGAGCTCTTTGGCTCAAGAGATAGTATGATCCGCTTTGATAT
GTCGGAATACATGGAAAAACATAGTGTGGCTAAGTTGATTGGTGCGCCTCCAGGATATGTAGGGTACGAGGAAGCAGGTC
AGCTGACAGAACGTGTCCGCCGTAACCCGTACAGCTTAATTTTATTGGATGAGATTGAGAAAGCACACCCTGATGTAATG
CATATGTTCTTGCAGATTCTTGATGACGGGCGTTTGACAGATGCGCAAGGGCGCACAGTTTCCTTCAAAGATGCAATCAT
CATTATGACCTCAAATGCGGGGACAGGTAAGGTTGAAGCAAGTGTTGGTTTTGGCGCTGCACGTGAAGGTCGTACGAATT
CAGTGCTTGGGGAACTCGGTAATTTCTTCAGTCCAGAATTCATGAACCGTTTTGATGCTATCATTGAATTCTCGGCATTG
AGCAAAGAAAACTTGCTTAAGATTGTGGATTTAATGTTGGATGAAGTCAATACTCAAATCGCTCAAAATGATATTCATCT
TGATGTCACACAGGCCGTTAAAGAAAAACTTGTTGACCTAGGTTATGATCCGAAAATGGGAGCACGTCCATTGCGTCGTA
CCATCCAAGATAATATCGAGGACGCTATTGCAGATTTTTACATTGAGCATCCTGAGTATAAAGAATTACTTGCAGATTTG
GTTGATGATAAGATTGTTATTGTGAATAAGCCTGAAGAAGTAAAGGACACAGCGGATACATCTGATAATGAAGATGAAGA
GAAATAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (284-383)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (640-710)

• ATPase family associated with various cellular activities (AAA) (AAA) (146-265)

• AAA domain (Cdc48 subfamily) (AAA_2) (469-634)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	86.631	100	0.866
clpE	Streptococcus mutans UA159	77.675	100	0.786
clpE	Streptococcus pneumoniae TIGR4	77.839	97.727	0.761
clpE	Streptococcus pneumoniae Rx1	77.839	97.727	0.761
clpE	Streptococcus pneumoniae D39	77.839	97.727	0.761
clpE	Streptococcus pneumoniae R6	77.839	97.727	0.761
clpC	Bacillus subtilis subsp. subtilis str. 168	50.367	91.043	0.459
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.961	81.952	0.393
clpC	Streptococcus pneumoniae Rx1	47.097	82.888	0.39
clpC	Streptococcus pneumoniae D39	47.097	82.888	0.39
clpC	Streptococcus pneumoniae TIGR4	46.935	82.888	0.389
clpC	Streptococcus mutans UA159	46.688	82.754	0.386
clpC	Streptococcus thermophilus LMD-9	46.006	83.69	0.385
clpC	Streptococcus thermophilus LMG 18311	45.645	82.888	0.378