Detailed information    

insolico Bioinformatically predicted

Overview

Name   braS   Type   Regulator
Locus tag   LLZ98_RS10945 Genome accession   NZ_CP086215
Coordinates   2214126..2215013 (+) Length   295 a.a.
NCBI ID   WP_000143425.1    Uniprot ID   A0A389PV50
Organism   Staphylococcus aureus strain Patient 14 Isolate 02     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2209126..2220013
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLZ98_RS10915 (LLZ98_10920) - 2209858..2210619 (+) 762 WP_000323441.1 alpha/beta hydrolase family protein -
  LLZ98_RS10920 (LLZ98_10925) - 2210864..2211319 (+) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  LLZ98_RS14370 - 2211441..2211542 (+) 102 WP_000731976.1 SE2200 family small protein -
  LLZ98_RS10930 (LLZ98_10935) - 2211602..2213026 (-) 1425 WP_000953755.1 alkaline phosphatase -
  LLZ98_RS10935 (LLZ98_10940) - 2213224..2213424 (+) 201 WP_000604730.1 hypothetical protein -
  LLZ98_RS10940 (LLZ98_10945) braR 2213450..2214115 (+) 666 WP_000697877.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  LLZ98_RS10945 (LLZ98_10950) braS 2214126..2215013 (+) 888 WP_000143425.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  LLZ98_RS10950 (LLZ98_10955) - 2215121..2215876 (+) 756 WP_000923760.1 ABC transporter ATP-binding protein -
  LLZ98_RS10955 (LLZ98_10960) - 2215873..2217873 (+) 2001 WP_000776750.1 ABC transporter permease -
  LLZ98_RS10960 (LLZ98_10965) - 2218532..2218645 (+) 114 Protein_2129 hypothetical protein -
  LLZ98_RS10965 (LLZ98_10970) - 2219027..2219287 (+) 261 WP_001791974.1 hypothetical protein -
  LLZ98_RS10970 (LLZ98_10975) - 2219297..2219794 (+) 498 WP_001065268.1 glutathione peroxidase -
  LLZ98_RS10975 (LLZ98_10980) - 2219902..2219994 (-) 93 WP_010956583.1 hypothetical protein -

Sequence

Protein


Download         Length: 295 a.a.        Molecular weight: 34006.28 Da        Isoelectric Point: 6.0874

>NTDB_id=623820 LLZ98_RS10945 WP_000143425.1 2214126..2215013(+) (braS) [Staphylococcus aureus strain Patient 14 Isolate 02]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide


Download         Length: 888 bp        

>NTDB_id=623820 LLZ98_RS10945 WP_000143425.1 2214126..2215013(+) (braS) [Staphylococcus aureus strain Patient 14 Isolate 02]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(191-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A389PV50

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braS Staphylococcus aureus N315

100

100

1