Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   M5T36_RS09395 Genome accession   NZ_CP103623
Coordinates   1932502..1933158 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 3985     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1927502..1938158
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M5T36_RS09365 (M5T36_09365) dcyD 1928382..1929368 (+) 987 WP_001128219.1 D-cysteine desulfhydrase -
  M5T36_RS09370 (M5T36_09370) tcyL 1929383..1930051 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  M5T36_RS09375 (M5T36_09375) tcyN 1930048..1930800 (+) 753 WP_001272987.1 L-cystine ABC transporter ATP-binding protein TcyN -
  M5T36_RS09380 (M5T36_09380) sdiA 1931030..1931752 (+) 723 WP_001154267.1 transcriptional regulator SdiA -
  M5T36_RS09385 (M5T36_09385) yecF 1931819..1932043 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  M5T36_RS09390 (M5T36_09390) yecU 1932030..1932206 (-) 177 WP_000590347.1 protein YecU -
  M5T36_RS23830 - 1932289..1932360 (-) 72 Protein_1839 transcriptional regulator -
  M5T36_RS09395 (M5T36_09395) letA 1932502..1933158 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  M5T36_RS09400 (M5T36_09400) uvrC 1933155..1934987 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  M5T36_RS09405 (M5T36_09405) pgsA 1935044..1935592 (+) 549 WP_001160188.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  M5T36_RS09425 (M5T36_09425) yecA 1936241..1936906 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=623717 M5T36_RS09395 WP_000611335.1 1932502..1933158(+) (letA) [Escherichia coli strain 3985]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=623717 M5T36_RS09395 WP_000611335.1 1932502..1933158(+) (letA) [Escherichia coli strain 3985]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486