Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   SA957_RS10245 Genome accession   NC_022442
Coordinates   2049734..2050450 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus subsp. aureus SA957     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2044734..2055450
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SA957_RS10215 (SA957_1873) - 2044951..2045577 (+) 627 WP_000522383.1 nitroreductase family protein -
  SA957_RS10220 (SA957_1874) - 2045938..2046723 (+) 786 WP_000867953.1 carbon-nitrogen family hydrolase -
  SA957_RS15245 hld 2047322..2047402 (-) 81 WP_000046023.1 delta-hemolysin -
  SA957_RS10230 (SA957_1876) agrB 2047692..2048261 (+) 570 WP_001105712.1 accessory gene regulator AgrB -
  SA957_RS10235 (SA957_1877) agrD 2048258..2048398 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  SA957_RS10240 agrC 2048423..2049715 (+) 1293 WP_031844950.1 quorum-sensing sensor histidine kinase AgrC -
  SA957_RS10245 (SA957_1879) agrA 2049734..2050450 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  SA957_RS10250 - 2050522..2050629 (+) 108 WP_031844951.1 hypothetical protein -
  SA957_RS10255 (SA957_1880) - 2050817..2051776 (-) 960 WP_001253300.1 carbohydrate kinase family protein -
  SA957_RS10260 (SA957_1881) - 2051773..2053257 (-) 1485 WP_000141422.1 sucrose-6-phosphate hydrolase -
  SA957_RS10265 (SA957_1882) - 2053406..2054356 (-) 951 WP_000790321.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=62371 SA957_RS10245 WP_000688492.1 2049734..2050450(+) (agrA) [Staphylococcus aureus subsp. aureus SA957]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=62371 SA957_RS10245 WP_000688492.1 2049734..2050450(+) (agrA) [Staphylococcus aureus subsp. aureus SA957]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment