Detailed information NTG0623588

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: M5T19_RS21755
• Genome accession: NZ_CP103596
• Coordinates: 4493529..4494554 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli strain 4848
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4488529..4499554

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M5T19_RS21735 (M5T19_21735)	-	4488876..4489856 (+)	981	WP_000399648.1	IS110-like element IS621 family transposase	-
M5T19_RS21740 (M5T19_21740)	yiiX	4490091..4490699 (+)	609	WP_000797353.1	YiiX family permuted papain-like enzyme	-
M5T19_RS21745 (M5T19_21745)	rpmE	4490760..4490972 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
M5T19_RS21750 (M5T19_21750)	priA	4491175..4493373 (+)	2199	WP_001301269.1	primosomal protein N'	Machinery gene
M5T19_RS21755 (M5T19_21755)	cytR	4493529..4494554 (+)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
M5T19_RS21760 (M5T19_21760)	ftsN	4494646..4495605 (+)	960	WP_000068828.1	cell division protein FtsN	-
M5T19_RS21765 (M5T19_21765)	hslV	4495698..4496228 (+)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
M5T19_RS21770 (M5T19_21770)	hslU	4496238..4497569 (+)	1332	WP_001293341.1	HslU--HslV peptidase ATPase subunit	-
M5T19_RS21775 (M5T19_21775)	menA	4497636..4498562 (+)	927	WP_000139496.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
M5T19_RS21780 (M5T19_21780)	rraA	4498655..4499140 (+)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
M5T19_RS21785 (M5T19_21785)	zapB	4499225..4499470 (-)	246	WP_001296623.1	septal ring assembly protein ZapB	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=623588 M5T19_RS21755 WP_000644904.1 4493529..4494554(+) (cytR) [Escherichia coli strain 4848]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=623588 M5T19_RS21755 WP_000644904.1 4493529..4494554(+) (cytR) [Escherichia coli strain 4848]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACCGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGTTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAGCTGGAG
CTGCCTACAGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGCTATGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCGATGCAGCAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628