Detailed information    

insolico Bioinformatically predicted

Overview

Name   cytR   Type   Regulator
Locus tag   M5S63_RS24490 Genome accession   NZ_CP103521
Coordinates   5058466..5059458 (-) Length   330 a.a.
NCBI ID   WP_000224470.1    Uniprot ID   P0ACQ1
Organism   Escherichia coli strain 2779 - blood draw same patient as MB9267     
Function   promote competence gene expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 5053466..5064458
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M5S63_RS24480 (M5S63_24480) yieP 5056358..5057050 (+) 693 WP_001131177.1 FadR/GntR family transcriptional regulator -
  M5S63_RS24485 (M5S63_24485) mdtD 5057073..5058500 (+) 1428 WP_001280852.1 multidrug transporter subunit MdtD -
  M5S63_RS24490 (M5S63_24490) cytR 5058466..5059458 (-) 993 WP_000224470.1 ribose operon transcriptional repressor RbsR Regulator
  M5S63_RS24495 (M5S63_24495) rbsK 5059462..5060391 (-) 930 WP_021523308.1 ribokinase -
  M5S63_RS24500 (M5S63_24500) rbsB 5060520..5061407 (-) 888 WP_020233744.1 ribose ABC transporter substrate-binding protein RbsB -
  M5S63_RS24505 (M5S63_24505) rbsC 5061432..5062397 (-) 966 WP_000211858.1 ribose ABC transporter permease -
  M5S63_RS24510 (M5S63_24510) rbsA 5062402..5063907 (-) 1506 WP_000387770.1 ribose ABC transporter ATP-binding protein RbsA -
  M5S63_RS24515 (M5S63_24515) rbsD 5063915..5064334 (-) 420 WP_000715936.1 D-ribose pyranase -

Sequence

Protein


Download         Length: 330 a.a.        Molecular weight: 36611.90 Da        Isoelectric Point: 5.2141

>NTDB_id=622682 M5S63_RS24490 WP_000224470.1 5058466..5059458(-) (cytR) [Escherichia coli strain 2779 - blood draw same patient as MB9267]
MATMKDVARLAGVSTSTVSHVINKDRFVSEAITAKVEAAIKELNYAPSALARSLKLNQTHTIGMLITASTNPFYSELVRG
VERSCFERGYSLVLCNTEGDEQRMNRNLETLMQKRVDGLLLLCTETHQPSREIMQRYPTVPTVMMDWAPFDGDSDLIQDN
SLLGGDLATQYLIDKGHTRIACITGPLDKTPARLRLEGYRAAMKRAGLNIPDGYEVTGDFEFNGGFDAMRQLLSHPLRPQ
AVFTGNDAMAVGVYQALYQAELQVPQDIAVIGYDDIELASFMTPPLTTIHQPKDELGELAIDVLIHRITQPTLQQQRLQL
TPILMERGSA

Nucleotide


Download         Length: 993 bp        

>NTDB_id=622682 M5S63_RS24490 WP_000224470.1 5058466..5059458(-) (cytR) [Escherichia coli strain 2779 - blood draw same patient as MB9267]
TTGGCTACAATGAAAGATGTTGCCCGCCTGGCGGGCGTTTCTACCTCAACAGTTTCTCACGTTATCAATAAAGATCGCTT
CGTCAGTGAAGCGATTACCGCCAAAGTTGAAGCGGCGATTAAAGAACTCAATTACGCGCCATCAGCCCTGGCGCGTAGCC
TCAAACTCAATCAAACACATACCATTGGCATGTTGATCACTGCCAGTACCAATCCTTTCTATTCAGAACTGGTGCGTGGC
GTTGAACGCAGCTGCTTCGAACGCGGTTATAGTCTCGTCCTTTGCAATACTGAAGGCGATGAACAGCGGATGAATCGCAA
TCTGGAAACGCTGATGCAAAAACGCGTTGATGGCTTGCTGTTACTGTGCACCGAAACGCATCAACCTTCGCGTGAAATCA
TGCAACGTTATCCGACAGTGCCTACTGTGATGATGGACTGGGCTCCGTTCGATGGCGACAGCGATCTTATTCAGGATAAC
TCGTTGCTGGGCGGAGACTTAGCAACGCAATATCTGATCGATAAAGGTCATACCCGTATCGCCTGTATTACCGGTCCGCT
GGATAAAACTCCGGCGCGCCTGCGGTTGGAAGGTTATCGGGCGGCGATGAAACGTGCGGGTCTCAACATTCCTGATGGCT
ATGAAGTCACTGGTGATTTTGAATTTAACGGCGGGTTTGACGCCATGCGCCAACTGTTATCACATCCGCTGCGTCCTCAG
GCCGTCTTTACCGGAAATGACGCTATGGCTGTTGGCGTTTACCAGGCGCTGTATCAGGCAGAGTTACAGGTTCCGCAGGA
TATCGCGGTGATTGGCTATGACGATATCGAACTGGCAAGCTTTATGACGCCACCATTAACCACTATCCACCAACCGAAAG
ATGAACTGGGGGAGCTGGCGATTGATGTACTCATCCATCGGATAACCCAGCCGACCCTTCAGCAACAACGATTACAACTT
ACTCCGATTCTGATGGAACGCGGTTCGGCTTAG

Domains

Predicted by InterProScan.

Periplasmic binding protein-like domain (Peripla_BP_3)

(169-329)

Bacterial regulatory proteins, lacI family (LacI)

(3-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0ACQ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cytR Vibrio parahaemolyticus RIMD 2210633

37.048

100

0.373
  cytR Vibrio cholerae C6706

39.088

93.03

0.364