Detailed information NTG0622373

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: LL045_RS03035
• Genome accession: NZ_CP086083
• Coordinates: 596429..598879 (+)
• Length: 816 a.a.
• NCBI ID: WP_104143440.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain EIP20A
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 591429..603879

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LL045_RS03010 (LL045_03010)	-	592192..592704 (+)	513	WP_012897343.1	adenine phosphoribosyltransferase	-
LL045_RS03015 (LL045_03015)	rpoE	592921..593484 (+)	564	WP_012897344.1	DNA-directed RNA polymerase subunit delta	-
LL045_RS03020 (LL045_03020)	mltG	593621..595273 (+)	1653	WP_394530357.1	endolytic transglycosylase MltG	-
LL045_RS03025 (LL045_03025)	greA	595334..595807 (+)	474	WP_025016857.1	transcription elongation factor GreA	-
LL045_RS03030 (LL045_03030)	-	595984..596439 (+)	456	WP_010905471.1	CtsR family transcriptional regulator	-
LL045_RS03035 (LL045_03035)	clpC	596429..598879 (+)	2451	WP_104143440.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
LL045_RS03040 (LL045_03040)	hpf	599014..599571 (+)	558	WP_394530358.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
LL045_RS03045 (LL045_03045)	eno	599759..601060 (+)	1302	WP_010905473.1	surface-displayed alpha-enolase	-
LL045_RS03050 (LL045_03050)	-	601176..601847 (-)	672	WP_058205272.1	ABC transporter ATP-binding protein	-
LL045_RS03055 (LL045_03055)	-	601850..602923 (-)	1074	WP_394530359.1	ABC transporter permease	-
LL045_RS03060 (LL045_03060)	-	602935..603504 (-)	570	WP_038599617.1	TetR/AcrR family transcriptional regulator	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90422.82 Da
• Isoelectric Point: 6.5300

>NTDB_id=622373 LL045_RS03035 WP_104143440.1 596429..598879(+) (clpC) [Lactococcus lactis subsp. lactis strain EIP20A]
MKFENIKYTPTLDRILEKAEEYAHQYQYGTIESAHLLAAMATTSGSIAYSLLAGMNVDSSDLLIDLEDLSSHVKVKRSTL
RFSPRAEEVMTAASFLAIHNNSEAVGTEHLLYALLQVEDGFGLQLLKLQKINIVSLRKELEKRTGLKVPESKKAVTPMSK
RKMAKGVAENSTTPTLDSVSSDLTEEARLGKLDPMIGREAEIDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSSDPDVIIFIDELHTIIGAGGGMDSVNDAANILKPALAR
GDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDEAIAILQGLREKFEDYHQVKFTDQAIKSAVMLSVRYMTSRK
LPDKAIDLLDEAAAAVKISVKNQQAKRLDLEKELAEAQEELSEAVIKLDIKASRTKEKAVEKIADKIYKFSVKEDKRQEV
TDQAVVAVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGVADSRRPMGSFMFLGPTGVGK
TELAKALADSVFGNEDNMIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHPDVFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATALRDDKTVGFGAKNITADYSAMKSRILEELKRHYRPEFLNRIDENIVF
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAVKLIAEVGFDPEYGARPLRKALQKEVEDLLSEQLLSGEIKAGNH
VSIGASNKKIKIAQIV

Nucleotide

• Length: 2451 bp

>NTDB_id=622373 LL045_RS03035 WP_104143440.1 596429..598879(+) (clpC) [Lactococcus lactis subsp. lactis strain EIP20A]
ATGAAATTTGAAAATATAAAATATACACCAACGCTTGACCGAATTTTAGAAAAAGCGGAAGAGTACGCTCACCAATATCA
ATATGGCACCATTGAAAGTGCACATTTACTGGCTGCAATGGCAACGACCTCAGGCTCAATTGCTTACAGCCTTCTTGCAG
GAATGAATGTTGATTCTTCTGACTTACTAATTGATTTAGAGGATTTATCAAGTCATGTTAAGGTCAAACGTTCAACTTTA
CGTTTTTCACCTCGTGCAGAGGAAGTGATGACTGCGGCAAGTTTTTTAGCAATTCATAATAACTCCGAAGCCGTTGGAAC
AGAACACCTGCTTTATGCCCTACTTCAAGTAGAAGATGGATTTGGTCTTCAACTTCTAAAATTACAAAAAATCAATATTG
TATCTTTGCGAAAAGAGCTTGAGAAAAGAACTGGACTCAAAGTTCCAGAAAGTAAAAAAGCTGTGACTCCAATGTCAAAA
CGCAAGATGGCAAAGGGAGTTGCAGAAAATTCAACGACGCCAACGTTAGACTCTGTATCCTCAGATTTAACCGAAGAAGC
TCGTTTGGGTAAACTTGACCCAATGATTGGACGAGAAGCTGAAATTGACCGTTTGATTCATATTCTCAGCCGCAGAACAA
AAAATAATCCTGTTTTAGTTGGAGAGCCCGGTGTTGGGAAATCAGCAATTATTGAAGGTTTGGCCCAAAGAATTGTCAAT
GGTCAAGTTCCAATTGGTTTGATGAATAGTCGAATTATGGCATTGAATATGGCGACTGTTGTTGCTGGGACAAAATTTAG
AGGTGAATTTGAGGATCGTTTGACAGCTATTGTTGAAGAAGTTAGCAGTGATCCAGATGTCATTATTTTCATTGATGAAT
TACACACAATCATTGGTGCTGGTGGCGGTATGGATTCTGTCAATGATGCCGCAAATATTTTGAAACCAGCGCTTGCTCGT
GGTGATTTTCAAATGGTCGGAGCAACAACCTATCATGAATATCAAAAATATATTGAAAAGGATGAAGCTTTAGAACGCCG
TTTGGCGAGAATAAATGTTGATGAGCCAAGTCCAGATGAAGCGATTGCTATTTTGCAAGGCTTACGTGAAAAATTTGAAG
ACTATCATCAAGTGAAATTTACTGACCAAGCCATTAAAAGTGCTGTAATGCTCAGTGTTCGTTATATGACTAGCCGAAAA
TTGCCTGACAAAGCCATTGATTTACTTGATGAAGCTGCAGCAGCGGTGAAAATTTCTGTCAAAAATCAACAAGCAAAACG
TCTTGATTTAGAAAAAGAACTAGCCGAAGCTCAAGAAGAATTATCAGAAGCTGTCATTAAACTTGATATCAAAGCGTCTC
GTACAAAAGAAAAAGCAGTTGAAAAAATTGCTGACAAGATTTATAAATTCTCAGTAAAAGAAGATAAACGTCAAGAAGTT
ACTGACCAAGCTGTTGTTGCTGTTGCCTCAACACTGACAGGTGTTCCAATCACACAAATGACTAAGTCTGAAAGTGATCG
TTTAATCAATCTTGAAAAAGAATTACACAAACGAGTTGTTGGACAAGAAGAAGCTATTTCTGCCGTTTCAAGAGCCATTC
GTCGGGCACGTTCTGGTGTTGCTGACAGTCGCCGTCCAATGGGTTCTTTCATGTTCCTTGGACCAACAGGGGTCGGTAAA
ACCGAACTTGCTAAAGCACTGGCTGACAGTGTGTTTGGTAATGAAGATAATATGATTCGTGTTGACATGAGTGAATTCAT
GGAAAAACATTCGACTTCACGCTTGATTGGAGCTCCTCCAGGGTATGTAGGTTATGATGAGGGTGGTCAATTGACAGAAC
GCGTTCGTAATAAACCATATTCTGTTGTTCTTTTAGATGAAGTCGAAAAAGCTCATCCTGACGTTTTCAACATCATGTTG
CAAATTCTAGATGATGGCTTTGTGACTGATACTAAAGGTCGTAAAGTTGATTTCAGAAATACAATTATTATCATGACTTC
AAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACAGTTGGTTTTGGCGCTAAAAATATCACAGCTGATTATTCAGCCA
TGAAATCAAGAATATTAGAAGAGCTTAAACGTCATTATCGTCCTGAGTTTCTTAATCGAATTGATGAAAATATTGTTTTC
CATTCATTGGAAAGTCAAGAGATTGAACAAATTGTTAAAATTATGAGTAAATCTTTGATTAAACGTCTGGCAGAACAAGA
TATTCATGTTAAACTCACACCGTCAGCGGTGAAACTAATTGCTGAGGTAGGTTTTGACCCAGAATATGGTGCACGTCCGC
TCCGCAAGGCACTTCAAAAAGAAGTCGAAGACCTTTTAAGTGAACAATTGCTCTCTGGTGAAATCAAAGCAGGTAATCAT
GTTTCAATTGGTGCATCTAATAAAAAAATTAAAATCGCTCAAATTGTTTGA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-802)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-334)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (19-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-144)

• AAA lid domain (AAA_lid_9) (357-453)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	99.755	100	0.998
clpC	Streptococcus thermophilus LMG 18311	50.903	100	0.518
clpC	Streptococcus thermophilus LMD-9	50.542	100	0.515
clpC	Streptococcus pneumoniae Rx1	48.918	100	0.499
clpC	Streptococcus pneumoniae D39	48.918	100	0.499
clpC	Streptococcus pneumoniae TIGR4	48.798	100	0.498
clpC	Bacillus subtilis subsp. subtilis str. 168	50.499	98.284	0.496
clpC	Streptococcus mutans UA159	48.558	100	0.495
clpE	Streptococcus mutans UA159	47.692	79.657	0.38
clpC	Lactococcus lactis subsp. cremoris KW2	46.87	80.27	0.376
clpE	Streptococcus pneumoniae TIGR4	47.528	76.838	0.365
clpE	Streptococcus pneumoniae Rx1	47.528	76.838	0.365
clpE	Streptococcus pneumoniae D39	47.528	76.838	0.365
clpE	Streptococcus pneumoniae R6	47.528	76.838	0.365