Detailed information NTG0622360

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LL047_RS11740
• Genome accession: NZ_CP086072
• Coordinates: 2296902..2297930 (-)
• Length: 342 a.a.
• NCBI ID: WP_010906347.1
• Uniprot ID: A0AAP4JQE3
• Organism: Lactococcus lactis subsp. lactis strain EIP33
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2291902..2302930

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LL047_RS11715 (LL047_11680)	-	2292188..2292685 (-)	498	WP_021214977.1	nitroreductase family protein	-
LL047_RS11720 (LL047_11685)	-	2292672..2292881 (-)	210	WP_003132661.1	hypothetical protein	-
LL047_RS11725 (LL047_11690)	-	2292878..2293705 (-)	828	WP_010906344.1	radical SAM protein	-
LL047_RS11730 (LL047_11695)	-	2293698..2295821 (-)	2124	WP_010906345.1	radical SAM protein	-
LL047_RS11735 (LL047_11700)	-	2295924..2296781 (-)	858	WP_010906346.1	transcriptional regulator	-
LL047_RS11740 (LL047_11705)	sepM	2296902..2297930 (-)	1029	WP_010906347.1	SepM family pheromone-processing serine protease	Regulator
LL047_RS11745 (LL047_11710)	coaD	2297917..2298414 (-)	498	WP_010906348.1	pantetheine-phosphate adenylyltransferase	-
LL047_RS11750 (LL047_11715)	rsmD	2298462..2299001 (-)	540	WP_015427191.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LL047_RS11755 (LL047_11720)	-	2299172..2300392 (-)	1221	WP_003132654.1	MFS transporter	-
LL047_RS11760 (LL047_11725)	lmrP	2300476..2301702 (-)	1227	WP_021214981.1	multidrug efflux MFS transporter LmrP	-
LL047_RS11765 (LL047_11730)	-	2301890..2302384 (+)	495	WP_010906351.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 342 a.a.
• Molecular weight: 37379.98 Da
• Isoelectric Point: 9.9183

>NTDB_id=622360 LL047_RS11740 WP_010906347.1 2296902..2297930(-) (sepM) [Lactococcus lactis subsp. lactis strain EIP33]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKTAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1029 bp

>NTDB_id=622360 LL047_RS11740 WP_010906347.1 2296902..2297930(-) (sepM) [Lactococcus lactis subsp. lactis strain EIP33]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
AACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGCAGCAACAATTACCTTGGAGCCAAAACCGCAGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (134-194)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (227-338)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.491