Detailed information    

insolico Bioinformatically predicted

Overview

Name   cytR   Type   Regulator
Locus tag   M5T42_RS22905 Genome accession   NZ_CP103465
Coordinates   4737615..4738607 (-) Length   330 a.a.
NCBI ID   WP_000224470.1    Uniprot ID   P0ACQ1
Organism   Escherichia coli O25b:H4-ST131 strain 5392     
Function   promote competence gene expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 4732615..4743607
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M5T42_RS22895 (M5T42_22895) yieP 4735507..4736199 (+) 693 WP_001131164.1 FadR/GntR family transcriptional regulator -
  M5T42_RS22900 (M5T42_22900) mdtD 4736222..4737649 (+) 1428 WP_001280867.1 multidrug transporter subunit MdtD -
  M5T42_RS22905 (M5T42_22905) cytR 4737615..4738607 (-) 993 WP_000224470.1 ribose operon transcriptional repressor RbsR Regulator
  M5T42_RS22910 (M5T42_22910) rbsK 4738611..4739540 (-) 930 WP_001545694.1 ribokinase -
  M5T42_RS22915 (M5T42_22915) rbsB 4739666..4740556 (-) 891 WP_001056273.1 ribose ABC transporter substrate-binding protein RbsB -
  M5T42_RS22920 (M5T42_22920) rbsC 4740581..4741546 (-) 966 WP_000211858.1 ribose ABC transporter permease -
  M5T42_RS22925 (M5T42_22925) rbsA 4741551..4743056 (-) 1506 WP_000387770.1 ribose ABC transporter ATP-binding protein RbsA -
  M5T42_RS22930 (M5T42_22930) rbsD 4743064..4743483 (-) 420 WP_001296586.1 D-ribose pyranase -

Sequence

Protein


Download         Length: 330 a.a.        Molecular weight: 36611.90 Da        Isoelectric Point: 5.2141

>NTDB_id=622265 M5T42_RS22905 WP_000224470.1 4737615..4738607(-) (cytR) [Escherichia coli O25b:H4-ST131 strain 5392]
MATMKDVARLAGVSTSTVSHVINKDRFVSEAITAKVEAAIKELNYAPSALARSLKLNQTHTIGMLITASTNPFYSELVRG
VERSCFERGYSLVLCNTEGDEQRMNRNLETLMQKRVDGLLLLCTETHQPSREIMQRYPTVPTVMMDWAPFDGDSDLIQDN
SLLGGDLATQYLIDKGHTRIACITGPLDKTPARLRLEGYRAAMKRAGLNIPDGYEVTGDFEFNGGFDAMRQLLSHPLRPQ
AVFTGNDAMAVGVYQALYQAELQVPQDIAVIGYDDIELASFMTPPLTTIHQPKDELGELAIDVLIHRITQPTLQQQRLQL
TPILMERGSA

Nucleotide


Download         Length: 993 bp        

>NTDB_id=622265 M5T42_RS22905 WP_000224470.1 4737615..4738607(-) (cytR) [Escherichia coli O25b:H4-ST131 strain 5392]
TTGGCTACAATGAAAGATGTTGCCCGCCTGGCGGGCGTTTCTACCTCAACAGTTTCTCACGTTATCAATAAAGATCGCTT
CGTCAGTGAAGCGATTACAGCCAAAGTTGAAGCGGCGATTAAAGAACTCAATTACGCGCCATCAGCTCTGGCGCGTAGCC
TCAAACTCAATCAAACACATACCATTGGCATGTTGATCACTGCCAGTACCAATCCTTTCTATTCAGAACTGGTGCGTGGC
GTTGAACGCAGCTGCTTCGAACGCGGTTATAGTCTTGTCCTTTGCAATACCGAAGGCGATGAACAGCGGATGAATCGCAA
TCTGGAAACGCTGATGCAAAAACGCGTTGATGGCTTGCTGTTACTGTGCACCGAAACGCATCAGCCTTCGCGTGAAATCA
TGCAACGTTATCCGACAGTGCCTACCGTGATGATGGACTGGGCTCCGTTCGATGGCGACAGCGATCTTATTCAGGATAAC
TCGTTGCTGGGCGGAGACTTAGCAACGCAATATCTGATCGATAAAGGTCATACCCGTATTGCCTGTATTACCGGTCCGCT
GGATAAAACTCCGGCGCGCCTGCGGTTGGAAGGTTATCGGGCGGCGATGAAACGTGCGGGTCTCAACATTCCTGATGGCT
ATGAAGTCACTGGTGATTTTGAATTTAACGGCGGGTTTGACGCTATGCGCCAACTGTTATCACATCCGCTGCGTCCTCAG
GCCGTCTTTACCGGAAATGACGCTATGGCTGTTGGCGTTTACCAGGCGTTATATCAGGCAGAGTTACAGGTTCCGCAGGA
TATCGCGGTGATTGGCTATGACGATATCGAACTGGCAAGCTTTATGACGCCACCATTAACAACTATACACCAACCGAAAG
ATGAACTGGGGGAGCTGGCGATTGATGTACTCATCCATCGGATAACCCAGCCGACCCTACAGCAACAACGATTACAACTT
ACTCCGATTCTGATGGAACGTGGTTCGGCTTAG

Domains

Predicted by InterProScan.

Periplasmic binding protein-like domain (Peripla_BP_3)

(169-329)

Bacterial regulatory proteins, lacI family (LacI)

(3-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0ACQ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cytR Vibrio parahaemolyticus RIMD 2210633

37.048

100

0.373
  cytR Vibrio cholerae C6706

39.088

93.03

0.364