Detailed information
Bioinformatically predicted
Overview
| Name | radA | Type | Machinery gene |
| Locus tag | LK443_RS02840 | Genome accession | NZ_CP085953 |
| Coordinates | 558493..559869 (+) | Length | 458 a.a. |
| NCBI ID | WP_227932042.1 | Uniprot ID | - |
| Organism | Granulicatella elegans strain FDAARGOS_1559 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 554674..631620 | 558493..559869 | within | 0 |
Gene organization within MGE regions
Location: 554674..631620
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LK443_RS02825 (LK443_02825) | - | 554674..556425 (-) | 1752 | WP_227932040.1 | IS1182 family transposase | - |
| LK443_RS02830 (LK443_02830) | - | 556592..557695 (-) | 1104 | WP_227932041.1 | ABC transporter ATP-binding protein | - |
| LK443_RS02835 (LK443_02835) | - | 557917..558480 (+) | 564 | WP_227932439.1 | dUTP diphosphatase | - |
| LK443_RS02840 (LK443_02840) | radA | 558493..559869 (+) | 1377 | WP_227932042.1 | DNA repair protein RadA | Machinery gene |
| LK443_RS02845 (LK443_02845) | - | 559900..561030 (+) | 1131 | WP_227932043.1 | PIN/TRAM domain-containing protein | - |
| LK443_RS02850 (LK443_02850) | - | 561142..562461 (-) | 1320 | WP_227932044.1 | ISL3 family transposase | - |
| LK443_RS02855 (LK443_02855) | - | 562806..563744 (+) | 939 | WP_227932045.1 | ABC transporter ATP-binding protein | - |
| LK443_RS02860 (LK443_02860) | - | 563756..564925 (+) | 1170 | WP_227932046.1 | ABC transporter permease | - |
| LK443_RS02865 (LK443_02865) | - | 564925..566019 (+) | 1095 | WP_227932047.1 | ABC transporter permease | - |
| LK443_RS02870 (LK443_02870) | - | 566178..566576 (+) | 399 | WP_322563570.1 | DUF554 family protein | - |
| LK443_RS02875 (LK443_02875) | - | 566652..566969 (+) | 318 | WP_227932048.1 | heavy metal-binding domain-containing protein | - |
| LK443_RS02880 (LK443_02880) | pflB | 567561..569876 (+) | 2316 | WP_227932049.1 | formate C-acetyltransferase | - |
| LK443_RS02890 (LK443_02890) | lacD | 571573..572577 (-) | 1005 | WP_227932050.1 | tagatose-bisphosphate aldolase | - |
| LK443_RS02895 (LK443_02895) | nagA | 572644..573804 (-) | 1161 | WP_227932051.1 | N-acetylglucosamine-6-phosphate deacetylase | - |
| LK443_RS02900 (LK443_02900) | - | 573850..575016 (-) | 1167 | WP_227932052.1 | SIS domain-containing protein | - |
| LK443_RS02905 (LK443_02905) | - | 575042..575773 (-) | 732 | WP_227932053.1 | GntR family transcriptional regulator | - |
| LK443_RS02910 (LK443_02910) | - | 576090..576710 (+) | 621 | WP_265416440.1 | serine dehydratase beta chain | - |
| LK443_RS02915 (LK443_02915) | sdaAA | 576732..577634 (+) | 903 | WP_227932055.1 | L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha | - |
| LK443_RS02920 (LK443_02920) | msrA | 577637..578158 (+) | 522 | WP_227932056.1 | peptide-methionine (S)-S-oxide reductase MsrA | - |
| LK443_RS02925 (LK443_02925) | brnQ | 578223..579539 (-) | 1317 | WP_227932057.1 | branched-chain amino acid transport system II carrier protein | - |
| LK443_RS02930 (LK443_02930) | dusB | 579735..580754 (+) | 1020 | WP_227932058.1 | tRNA dihydrouridine synthase DusB | - |
| LK443_RS02935 (LK443_02935) | lysS | 580885..582837 (+) | 1953 | WP_227932059.1 | lysine--tRNA ligase | - |
| LK443_RS02940 (LK443_02940) | - | 582901..583182 (+) | 282 | WP_039880650.1 | CD1845 family protein | - |
| LK443_RS02945 (LK443_02945) | - | 583267..584040 (+) | 774 | WP_227932060.1 | replication initiator protein A | - |
| LK443_RS02950 (LK443_02950) | - | 584037..584864 (+) | 828 | WP_227932061.1 | ATP-binding protein | - |
| LK443_RS02955 (LK443_02955) | - | 584857..585342 (+) | 486 | WP_007894980.1 | PcfB family protein | - |
| LK443_RS02960 (LK443_02960) | - | 585339..586073 (+) | 735 | WP_227932062.1 | BRO family protein | - |
| LK443_RS02965 (LK443_02965) | - | 586066..587856 (+) | 1791 | WP_227932063.1 | VirD4-like conjugal transfer protein, CD1115 family | - |
| LK443_RS02970 (LK443_02970) | - | 587918..588454 (+) | 537 | WP_001258251.1 | ClbS/DfsB family four-helix bundle protein | - |
| LK443_RS02975 (LK443_02975) | - | 588472..589940 (+) | 1469 | Protein_541 | PIN-like domain-containing protein | - |
| LK443_RS02980 (LK443_02980) | - | 590136..590447 (+) | 312 | WP_002839977.1 | hypothetical protein | - |
| LK443_RS02985 (LK443_02985) | - | 590449..590577 (+) | 129 | Protein_543 | Maff2 family mobile element protein | - |
| LK443_RS02990 (LK443_02990) | ltrA | 591303..593162 (+) | 1860 | WP_227931966.1 | group II intron reverse transcriptase/maturase | - |
| LK443_RS02995 (LK443_02995) | - | 593475..593681 (+) | 207 | WP_227932064.1 | helix-turn-helix domain-containing protein | - |
| LK443_RS03000 (LK443_03000) | - | 593851..594270 (+) | 420 | WP_227932065.1 | BlaI/MecI/CopY family transcriptional regulator | - |
| LK443_RS03005 (LK443_03005) | - | 594251..595615 (+) | 1365 | WP_227932066.1 | M56 family metallopeptidase | - |
| LK443_RS03010 (LK443_03010) | - | 595776..596828 (+) | 1053 | WP_227932067.1 | hypothetical protein | - |
| LK443_RS03015 (LK443_03015) | - | 597013..597441 (+) | 429 | WP_227932068.1 | hypothetical protein | - |
| LK443_RS03020 (LK443_03020) | - | 597511..599394 (+) | 1884 | WP_227932069.1 | hypothetical protein | - |
| LK443_RS03025 (LK443_03025) | - | 599414..600034 (+) | 621 | WP_227932070.1 | ATP-binding cassette domain-containing protein | - |
| LK443_RS03030 (LK443_03030) | - | 600163..600567 (+) | 405 | WP_227932071.1 | hypothetical protein | - |
| LK443_RS03035 (LK443_03035) | - | 600601..600891 (+) | 291 | WP_227932072.1 | DUF3847 domain-containing protein | - |
| LK443_RS03040 (LK443_03040) | mobQ | 601244..602878 (+) | 1635 | WP_227932073.1 | MobQ family relaxase | - |
| LK443_RS03045 (LK443_03045) | - | 602952..603125 (+) | 174 | WP_227932074.1 | hypothetical protein | - |
| LK443_RS03050 (LK443_03050) | - | 603308..603829 (+) | 522 | WP_227932075.1 | PcfB family protein | - |
| LK443_RS03055 (LK443_03055) | - | 604261..605331 (+) | 1071 | WP_227932076.1 | PDDEXK nuclease domain-containing protein | - |
| LK443_RS03060 (LK443_03060) | - | 605414..606115 (+) | 702 | WP_227932077.1 | replisome organizer | - |
| LK443_RS03065 (LK443_03065) | - | 606269..606493 (+) | 225 | WP_227932078.1 | hypothetical protein | - |
| LK443_RS03070 (LK443_03070) | - | 606497..608143 (+) | 1647 | WP_070738750.1 | recombinase family protein | - |
| LK443_RS03075 (LK443_03075) | - | 608147..608230 (+) | 84 | Protein_561 | Maff2 family mobile element protein | - |
| LK443_RS03080 (LK443_03080) | - | 608250..609113 (+) | 864 | WP_050139227.1 | VirB6/TrbL-like conjugal transfer protein, CD1112 family | - |
| LK443_RS03085 (LK443_03085) | - | 609131..609394 (+) | 264 | WP_047200001.1 | hypothetical protein | - |
| LK443_RS03090 (LK443_03090) | - | 609398..609787 (+) | 390 | WP_227932079.1 | PrgI family protein | - |
| LK443_RS03095 (LK443_03095) | - | 609699..612128 (+) | 2430 | WP_227932080.1 | VirB4-like conjugal transfer ATPase, CD1110 family | - |
| LK443_RS03100 (LK443_03100) | - | 612133..614265 (+) | 2133 | WP_227932081.1 | CHAP domain-containing protein | - |
| LK443_RS03105 (LK443_03105) | - | 614278..614514 (+) | 237 | WP_000711923.1 | hypothetical protein | - |
| LK443_RS03110 (LK443_03110) | - | 614492..616681 (+) | 2190 | WP_227932082.1 | CD1107 family mobile element protein | - |
| LK443_RS03115 (LK443_03115) | - | 616780..618486 (+) | 1707 | WP_227932083.1 | DNA topoisomerase 3 | - |
| LK443_RS03120 (LK443_03120) | - | 618571..619374 (+) | 804 | WP_002843620.1 | KilA-N domain-containing protein | - |
| LK443_RS03125 (LK443_03125) | - | 619458..626846 (+) | 7389 | WP_227932084.1 | helicase-related protein | - |
| LK443_RS03130 (LK443_03130) | ltrA | 627402..629072 (+) | 1671 | WP_227932085.1 | group II intron reverse transcriptase/maturase | - |
| LK443_RS03135 (LK443_03135) | - | 629161..630555 (+) | 1395 | Protein_573 | helicase | - |
| LK443_RS03140 (LK443_03140) | - | 630598..631257 (+) | 660 | WP_227932087.1 | DNA-binding protein | - |
| LK443_RS03145 (LK443_03145) | - | 631405..631620 (+) | 216 | WP_000036627.1 | helix-turn-helix domain-containing protein | - |
Sequence
Protein
Download Length: 458 a.a. Molecular weight: 50088.66 Da Isoelectric Point: 8.2115
>NTDB_id=621611 LK443_RS02840 WP_227932042.1 558493..559869(+) (radA) [Granulicatella elegans strain FDAARGOS_1559]
MAKATVSYLCSECGYVSPRYLGKCPNCGQWSTMEEYKEVATSSTKKQSLVSHSEEKNRAKPLRIDQVAYERVKRVETSMQ
ELDRVLGGGVVPGSLVLIGGDPGIGKSTLLLQVSSQLQKSGGSVLYVSGEESAAQVKMRAERLGMQADGFYIYPETNLQA
VVTQVEQLKPDYVIIDSIQTMAHPQATGIAGSVSQVRESTATLMRLAKLNQIAIFIVGHVTKEGALAGPRMLEHMVDTVL
YFEGEKHHSFRILRSVKNRFGSTNEIGVFEMMQDGLKEVVNPSEVFLEERLKGATGSAIVVSLEGTRPILAEVQCLLSPA
IFGNARRTTSGLDYNRVALLMAVLEKRAGLLLQNQDAYFKSTGGLKLNEPAIDLAIAMSIVSSYKEQGTAVDDCFVGEIG
LTGEIRRVNRISDRVKEAQKLGFKRIFIPKNNIDGWEFPKGIEVVGVSSVKEAIQKAF
MAKATVSYLCSECGYVSPRYLGKCPNCGQWSTMEEYKEVATSSTKKQSLVSHSEEKNRAKPLRIDQVAYERVKRVETSMQ
ELDRVLGGGVVPGSLVLIGGDPGIGKSTLLLQVSSQLQKSGGSVLYVSGEESAAQVKMRAERLGMQADGFYIYPETNLQA
VVTQVEQLKPDYVIIDSIQTMAHPQATGIAGSVSQVRESTATLMRLAKLNQIAIFIVGHVTKEGALAGPRMLEHMVDTVL
YFEGEKHHSFRILRSVKNRFGSTNEIGVFEMMQDGLKEVVNPSEVFLEERLKGATGSAIVVSLEGTRPILAEVQCLLSPA
IFGNARRTTSGLDYNRVALLMAVLEKRAGLLLQNQDAYFKSTGGLKLNEPAIDLAIAMSIVSSYKEQGTAVDDCFVGEIG
LTGEIRRVNRISDRVKEAQKLGFKRIFIPKNNIDGWEFPKGIEVVGVSSVKEAIQKAF
Nucleotide
Download Length: 1377 bp
>NTDB_id=621611 LK443_RS02840 WP_227932042.1 558493..559869(+) (radA) [Granulicatella elegans strain FDAARGOS_1559]
ATGGCAAAAGCAACCGTTAGCTATCTATGTTCAGAATGTGGGTATGTTTCTCCTAGATATTTAGGGAAATGTCCAAATTG
TGGACAATGGAGTACGATGGAAGAATATAAGGAAGTTGCTACAAGTAGTACTAAAAAACAATCTTTAGTGAGTCATTCTG
AAGAAAAAAATCGAGCAAAACCACTTCGTATTGATCAAGTTGCTTATGAACGTGTCAAACGTGTAGAAACTTCGATGCAA
GAATTAGATCGTGTATTAGGTGGTGGAGTCGTTCCTGGTTCTCTTGTATTAATTGGTGGAGACCCTGGAATTGGGAAGTC
TACTTTGTTATTACAAGTATCGAGTCAATTACAAAAATCAGGAGGCAGTGTTTTATATGTTTCAGGTGAGGAAAGTGCTG
CACAAGTAAAAATGCGTGCAGAACGTTTAGGGATGCAAGCAGATGGGTTTTATATTTATCCGGAAACAAATTTACAGGCT
GTAGTGACACAAGTCGAACAATTAAAGCCAGACTATGTGATTATCGATTCGATTCAGACAATGGCTCATCCGCAAGCAAC
AGGAATTGCAGGAAGTGTTTCTCAAGTAAGAGAATCAACGGCAACATTGATGAGATTAGCGAAGTTAAATCAAATTGCGA
TTTTTATTGTAGGACATGTAACGAAAGAAGGAGCTTTGGCAGGGCCTAGAATGTTGGAACATATGGTGGATACGGTATTG
TATTTTGAAGGGGAAAAACACCATAGTTTTAGGATTTTACGTTCGGTAAAAAATCGTTTCGGTTCGACAAATGAAATTGG
TGTATTTGAGATGATGCAAGATGGATTAAAAGAAGTGGTGAATCCGTCAGAAGTTTTCTTAGAGGAACGATTAAAAGGGG
CAACAGGATCTGCAATTGTTGTGTCGCTTGAAGGAACTCGTCCAATCTTAGCAGAAGTTCAATGTTTATTATCTCCAGCA
ATTTTTGGAAATGCTCGAAGAACAACGAGTGGATTGGATTATAATCGTGTAGCTCTACTAATGGCAGTATTAGAAAAGAG
AGCCGGATTATTGTTACAAAATCAAGATGCTTATTTCAAATCTACAGGCGGTTTGAAATTAAATGAACCAGCAATTGATT
TAGCGATTGCGATGAGTATTGTTTCAAGTTATAAAGAACAGGGAACAGCAGTAGATGATTGTTTTGTAGGAGAAATTGGA
TTAACGGGAGAAATTCGTCGTGTCAATCGTATTAGCGATCGTGTAAAGGAAGCACAAAAATTAGGGTTTAAACGAATTTT
TATCCCAAAAAATAATATCGATGGATGGGAATTTCCAAAAGGAATTGAAGTTGTCGGAGTTTCCTCTGTGAAAGAAGCCA
TTCAAAAAGCATTTTAA
ATGGCAAAAGCAACCGTTAGCTATCTATGTTCAGAATGTGGGTATGTTTCTCCTAGATATTTAGGGAAATGTCCAAATTG
TGGACAATGGAGTACGATGGAAGAATATAAGGAAGTTGCTACAAGTAGTACTAAAAAACAATCTTTAGTGAGTCATTCTG
AAGAAAAAAATCGAGCAAAACCACTTCGTATTGATCAAGTTGCTTATGAACGTGTCAAACGTGTAGAAACTTCGATGCAA
GAATTAGATCGTGTATTAGGTGGTGGAGTCGTTCCTGGTTCTCTTGTATTAATTGGTGGAGACCCTGGAATTGGGAAGTC
TACTTTGTTATTACAAGTATCGAGTCAATTACAAAAATCAGGAGGCAGTGTTTTATATGTTTCAGGTGAGGAAAGTGCTG
CACAAGTAAAAATGCGTGCAGAACGTTTAGGGATGCAAGCAGATGGGTTTTATATTTATCCGGAAACAAATTTACAGGCT
GTAGTGACACAAGTCGAACAATTAAAGCCAGACTATGTGATTATCGATTCGATTCAGACAATGGCTCATCCGCAAGCAAC
AGGAATTGCAGGAAGTGTTTCTCAAGTAAGAGAATCAACGGCAACATTGATGAGATTAGCGAAGTTAAATCAAATTGCGA
TTTTTATTGTAGGACATGTAACGAAAGAAGGAGCTTTGGCAGGGCCTAGAATGTTGGAACATATGGTGGATACGGTATTG
TATTTTGAAGGGGAAAAACACCATAGTTTTAGGATTTTACGTTCGGTAAAAAATCGTTTCGGTTCGACAAATGAAATTGG
TGTATTTGAGATGATGCAAGATGGATTAAAAGAAGTGGTGAATCCGTCAGAAGTTTTCTTAGAGGAACGATTAAAAGGGG
CAACAGGATCTGCAATTGTTGTGTCGCTTGAAGGAACTCGTCCAATCTTAGCAGAAGTTCAATGTTTATTATCTCCAGCA
ATTTTTGGAAATGCTCGAAGAACAACGAGTGGATTGGATTATAATCGTGTAGCTCTACTAATGGCAGTATTAGAAAAGAG
AGCCGGATTATTGTTACAAAATCAAGATGCTTATTTCAAATCTACAGGCGGTTTGAAATTAAATGAACCAGCAATTGATT
TAGCGATTGCGATGAGTATTGTTTCAAGTTATAAAGAACAGGGAACAGCAGTAGATGATTGTTTTGTAGGAGAAATTGGA
TTAACGGGAGAAATTCGTCGTGTCAATCGTATTAGCGATCGTGTAAAGGAAGCACAAAAATTAGGGTTTAAACGAATTTT
TATCCCAAAAAATAATATCGATGGATGGGAATTTCCAAAAGGAATTGAAGTTGTCGGAGTTTCCTCTGTGAAAGAAGCCA
TTCAAAAAGCATTTTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| radA | Streptococcus mitis NCTC 12261 |
65.939 |
100 |
0.659 |
| radA | Streptococcus pneumoniae Rx1 |
65.721 |
100 |
0.657 |
| radA | Streptococcus pneumoniae D39 |
65.721 |
100 |
0.657 |
| radA | Streptococcus pneumoniae R6 |
65.721 |
100 |
0.657 |
| radA | Streptococcus pneumoniae TIGR4 |
65.721 |
100 |
0.657 |
| radA | Streptococcus mitis SK321 |
65.502 |
100 |
0.655 |
| radA | Bacillus subtilis subsp. subtilis str. 168 |
59.389 |
100 |
0.594 |