Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC   Type   Machinery gene
Locus tag   LK401_RS02615 Genome accession   NZ_CP085952
Coordinates   495791..496312 (-) Length   173 a.a.
NCBI ID   WP_011272048.1    Uniprot ID   Q4QNA8
Organism   Haemophilus influenzae strain FDAARGOS_1560     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 490791..501312
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LK401_RS02585 (LK401_02585) - 491176..491766 (-) 591 WP_005686892.1 YjaG family protein -
  LK401_RS02590 (LK401_02590) nudC 491802..492596 (-) 795 WP_005686893.1 NAD(+) diphosphatase -
  LK401_RS02595 (LK401_02595) nfuA 492663..493259 (-) 597 WP_005649300.1 Fe-S biogenesis protein NfuA -
  LK401_RS02600 (LK401_02600) - 493335..494021 (-) 687 WP_011272045.1 ComF family protein -
  LK401_RS02605 (LK401_02605) comE 494034..495371 (-) 1338 WP_011272046.1 type IV pilus secretin PilQ Machinery gene
  LK401_RS02610 (LK401_02610) comD 495381..495794 (-) 414 WP_011272047.1 pilus assembly protein PilP Machinery gene
  LK401_RS02615 (LK401_02615) comC 495791..496312 (-) 522 WP_011272048.1 competence protein ComC Machinery gene
  LK401_RS02620 (LK401_02620) comB 496309..496814 (-) 506 Protein_492 competence protein ComB -
  LK401_RS02625 (LK401_02625) comA 496815..497612 (-) 798 WP_011272050.1 pilus assembly protein PilM Machinery gene
  LK401_RS02630 (LK401_02630) - 497711..500305 (+) 2595 WP_011272051.1 penicillin-binding protein 1A -
  LK401_RS02635 (LK401_02635) - 500378..501223 (+) 846 WP_011272052.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -

Sequence

Protein


Download         Length: 173 a.a.        Molecular weight: 19994.18 Da        Isoelectric Point: 10.0952

>NTDB_id=621579 LK401_RS02615 WP_011272048.1 495791..496312(-) (comC) [Haemophilus influenzae strain FDAARGOS_1560]
MKAFFNDPFTPFGKWLSQPFYVHGLTFLLLLSAVIFRPVLDYIEGSSRFHEIENELAVKRSELLHQQKILTSLQQQSESR
KLSPELAAQIIPLNKQIQRLAARNGLSQHLRWEMGQKPILHLQLTGHFEKTKTFLTALLANSSQLSVSRLQFIKPEDNPL
QTEIIFQLDKETK

Nucleotide


Download         Length: 522 bp        

>NTDB_id=621579 LK401_RS02615 WP_011272048.1 495791..496312(-) (comC) [Haemophilus influenzae strain FDAARGOS_1560]
ATGAAAGCTTTTTTTAACGATCCTTTTACTCCTTTTGGAAAATGGCTAAGTCAGCCTTTTTATGTGCACGGTTTAACCTT
TTTATTGCTATTAAGTGCGGTGATTTTTCGCCCCGTTTTAGATTATATCGAGGGGAGTTCACGTTTCCATGAAATTGAAA
ATGAGTTAGCGGTGAAACGTTCAGAATTGTTGCATCAACAGAAAATTTTAACTTCTTTACAGCAGCAGTCGGAAAGTCGA
AAACTTTCTCCAGAACTGGCTGCACAAATTATTCCTTTGAATAAACAAATTCAACGTTTAGCTGCGCGTAACGGTTTATC
TCAGCATTTACGTTGGGAAATGGGGCAAAAGCCTATTTTGCATTTACAGCTTACAGGTCATTTTGAGAAAACGAAGACAT
TTTTAACCGCACTTTTGGCTAATTCGTCACAGCTTTCAGTGAGTCGCTTGCAGTTTATCAAACCCGAAGACAACCCATTG
CAAACCGAGATCATTTTTCAGCTAGATAAGGAAACAAAATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QNA8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC Haemophilus influenzae 86-028NP

100

100

1
  comC Haemophilus influenzae Rd KW20

98.266

100

0.983