Detailed information NTG0621443

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: LK450_RS08925
• Genome accession: NZ_CP085939
• Coordinates: 1807157..1808224 (+)
• Length: 355 a.a.
• NCBI ID: WP_003026176.1
• Uniprot ID: A0A2I1UTR6
• Organism: Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1802157..1813224

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LK450_RS08910 (LK450_08910)	amiA3	1802371..1804350 (+)	1980	WP_018543580.1	peptide ABC transporter substrate-binding protein	Regulator
LK450_RS08915 (LK450_08915)	amiC	1804726..1806222 (+)	1497	WP_003031736.1	ABC transporter permease	Regulator
LK450_RS08920 (LK450_08920)	amiD	1806222..1807148 (+)	927	WP_003031796.1	oligopeptide ABC transporter permease OppC	Regulator
LK450_RS08925 (LK450_08925)	amiE	1807157..1808224 (+)	1068	WP_003026176.1	ABC transporter ATP-binding protein	Regulator
LK450_RS08930 (LK450_08930)	amiF	1808235..1809158 (+)	924	WP_003031730.1	ATP-binding cassette domain-containing protein	Regulator
LK450_RS08935 (LK450_08935)	-	1809301..1810125 (+)	825	WP_003031797.1	Cof-type HAD-IIB family hydrolase	-
LK450_RS08940 (LK450_08940)	-	1810199..1811164 (-)	966	WP_003031743.1	LacI family DNA-binding transcriptional regulator	-
LK450_RS08945 (LK450_08945)	-	1811145..1812602 (-)	1458	WP_003031721.1	sucrose-6-phosphate hydrolase	-

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39702.39 Da
• Isoelectric Point: 4.7502

>NTDB_id=621443 LK450_RS08925 WP_003026176.1 1807157..1808224(+) (amiE) [Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569]
MTQEKNVILTARDIVVEFDVRDKVLTAIRGVSLDLIEGEVLALVGESGSGKSVLTKTFTGMLEENGRVAQGTIDYRGQDL
TKLKSNKDWEPIRGVKIATIFQDPMTSLDPINTIGSQITEVIIKHQKKTPKEAKEMAVDYMNKVGIPDAEKRFNEYPFQY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIIDLLKSLQHEYEFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGELYSIPGTPPSLYSHLQGDAFALRSDYAMEIDFEEKPPQIYVTDTHWAK
TWLLHENAPKVNKPAVIDDLHEKISSKMGFAHLDA

Nucleotide

• Length: 1068 bp

>NTDB_id=621443 LK450_RS08925 WP_003026176.1 1807157..1808224(+) (amiE) [Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569]
ATGACACAAGAAAAAAATGTAATATTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGATAAAGTCTTAACAGC
CATTCGTGGTGTTTCGCTTGACCTTATCGAAGGTGAGGTTCTTGCACTTGTAGGAGAATCTGGTTCTGGTAAGTCTGTTT
TGACAAAGACATTTACAGGAATGTTAGAGGAAAATGGTCGAGTTGCTCAAGGAACGATTGATTACCGTGGACAAGATTTG
ACAAAATTGAAGTCTAATAAAGATTGGGAACCTATACGCGGTGTTAAAATTGCAACAATCTTCCAAGATCCGATGACGAG
TTTGGACCCTATTAACACAATTGGTAGCCAAATTACAGAAGTGATTATCAAGCATCAAAAGAAAACGCCAAAAGAAGCAA
AAGAAATGGCTGTTGACTATATGAATAAGGTCGGCATTCCTGATGCTGAAAAGCGTTTTAATGAATACCCATTCCAATAT
TCAGGAGGAATGCGTCAACGGATTGTTATCGCTATTGCGCTTGCTTGTCGACCTGATATCCTTATCTGTGATGAACCAAC
GACAGCGCTTGACGTTACGATTCAGGCACAAATCATTGATTTGTTGAAATCTTTGCAACACGAGTATGAATTCACAACTA
TTTTTATCACCCACGACCTGGGAGTGGTAGCAAGTATTGCAGATAAGGTTGCGGTTATGTATGCTGGTGAAATCGTTGAA
TACGGAACAGTAGAAGAAGTCTTTTACGATCCACGTCATCCTTACACTTGGAGTTTGTTATCTAGTCTACCTCAGTTGGC
AGATGATAAGGGTGAGTTGTATTCAATTCCTGGAACGCCGCCATCTCTCTATTCACATTTACAAGGAGATGCATTTGCCT
TGCGTTCAGATTATGCTATGGAAATTGATTTTGAAGAGAAACCGCCTCAAATTTATGTAACGGATACCCACTGGGCAAAA
ACATGGTTGTTACATGAGAATGCTCCAAAAGTGAATAAGCCAGCTGTTATTGATGATTTACACGAAAAAATTAGCTCAAA
AATGGGCTTTGCCCATTTAGACGCCTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A2I1UTR6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	86.119	99.437	0.856
amiE	Streptococcus thermophilus LMG 18311	84.703	99.437	0.842
amiE	Streptococcus thermophilus LMD-9	84.703	99.437	0.842
oppD	Streptococcus mutans UA159	56.215	99.718	0.561