Detailed information NTG0620728

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: NW953_RS12645
• Genome accession: NZ_CP102975
• Coordinates: 2572273..2574381 (+)
• Length: 702 a.a.
• NCBI ID: WP_258409428.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain 16CS0209
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2567273..2579381

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NW953_RS12620 (NW953_12620)	-	2567340..2567558 (+)	219	WP_000011687.1	sterile alpha motif-like domain-containing protein	-
NW953_RS12625 (NW953_12625)	-	2567946..2568377 (+)	432	WP_000875614.1	CHAP domain-containing protein	-
NW953_RS12630 (NW953_12630)	-	2568517..2569797 (-)	1281	WP_258409426.1	hydroxymethylglutaryl-CoA reductase, degradative	-
NW953_RS12635 (NW953_12635)	-	2570052..2571218 (+)	1167	WP_000151981.1	hydroxymethylglutaryl-CoA synthase	-
NW953_RS12640 (NW953_12640)	-	2571389..2571910 (-)	522	WP_258409427.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
NW953_RS12645 (NW953_12645)	clpE	2572273..2574381 (+)	2109	WP_258409428.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
NW953_RS12650 (NW953_12650)	-	2574448..2574618 (-)	171	WP_258409429.1	FeoB-associated Cys-rich membrane protein	-
NW953_RS12655 (NW953_12655)	feoB	2574631..2576625 (-)	1995	WP_258409430.1	ferrous iron transport protein B	-
NW953_RS12660 (NW953_12660)	-	2576637..2576864 (-)	228	WP_000932073.1	ferrous iron transport protein A	-
NW953_RS12665 (NW953_12665)	farE	2577080..2577991 (-)	912	Protein_2447	fatty acid efflux MMPL transporter FarE	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 78075.63 Da
• Isoelectric Point: 4.6911

>NTDB_id=620728 NW953_RS12645 WP_258409428.1 2572273..2574381(+) (clpE) [Staphylococcus aureus strain 16CS0209]
MNNNFFNSDFDSILRRMMQDMQNSNQTSNKKYYINGKEVSPEELAQLTQQGGNHSAEQSAQAFQQAALRQQGQQSGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISI
DISSLEAGTQYRGAFEENIQKLVEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNIMKDAALTRRFNEVLVNEPSAKDTVEILKGLREKFETHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAIDKVATEKRISELEHDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDANDIERLKNISSRLRSKIIGQDKAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKEA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIVICTSNAGFGNGTDQEYDDIMQEMKKFFRPEFLNRFNGIVEFLHLDKESLQEIINLLLDDVQVTLDKKGITMNV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDLDIEDNELVVKGKS

Nucleotide

• Length: 2109 bp

>NTDB_id=620728 NW953_RS12645 WP_258409428.1 2572273..2574381(+) (clpE) [Staphylococcus aureus strain 16CS0209]
ATGAATAACAATTTTTTCAATAGTGACTTCGATTCTATTTTACGAAGAATGATGCAAGACATGCAAAACTCAAATCAGAC
TAGTAACAAAAAGTACTATATTAATGGTAAAGAAGTTTCACCTGAAGAACTAGCGCAACTCACACAACAAGGTGGCAATC
ACTCTGCTGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACTAAGACAACAAGGTCAACAAAGTGGCAATGGCAATTAT
TTAGAACAAATTGGTCGTAACTTAACGCAAGAGGCTCGTGACGGATTATTAGATCCAGTCATCGGTCGTGATAAAGAAAT
CCAAGAAACTGCAGAAGTCTTAAGTAGACGCACTAAAAACAATCCTATCCTAGTCGGAGAAGCTGGAGTTGGTAAAACTG
CGATTGTCGAAGGTTTAGCGCAAGCAATCGTTGAAGGGAACGTACCTGCAGCAATCAAAGATAAAGAAATTATATCTATA
GATATTTCATCGCTTGAAGCTGGAACGCAATATCGTGGTGCCTTTGAAGAAAACATCCAAAAGTTAGTTGAAGGCGTTAA
ATCATCACAAAATGCTGTGCTCTTCTTTGACGAAATTCACCAAATCATCGGTTCCGGTGCAACAGGAAGTGATTCCGGTA
GTAAAGGTTTATCTGATATTTTAAAACCAGCATTAAGTCGTGGTGAAATTTCTATTATTGGTGCAACAACACAAGATGAA
TATCGAAATAATATCATGAAAGACGCTGCATTAACACGTCGTTTTAACGAGGTACTGGTTAACGAACCAAGCGCAAAAGA
TACGGTTGAAATTTTAAAAGGACTTCGCGAAAAATTTGAAACACACCATCAAGTCAAATTACCTGATGACGTATTAAAGG
CATGTGTAGACTTATCCATTCAATATATTCCACAACGCTTATTACCTGACAAAGCAATCGATGTATTAGATATTACAGCT
GCACATTTATCTGCACAAAGCCCTGCTATTGATAAAGTCGCGACTGAAAAACGTATTTCTGAATTGGAACATGATAAGCG
TAAAGCTGTAAGTGCTGAAGAATATAAAAAAGCAGATGACATTCAAAATGAAATCAAATCTCTACAAGATAAATTAGAAA
ACAGTAATGGTGAACATACTGCAGTAGCAACGGTGCATGATATTTCTGATACCATTCAACGATTAACTGGTATTCCTGTA
TCTCAAATGGATGCCAATGACATTGAACGTTTAAAAAATATTTCTAGTCGTTTAAGAAGTAAAATCATCGGTCAAGATAA
AGCTGTAGAAATGGTTTCTCGTGCCATCCGTCGTAATCGAGCTGGTTTTGATGATGGCAATCGTCCAATTGGTAGCTTCC
TATTTGTCGGTCCTACTGGTGTTGGTAAAACAGAGCTTGCCAAACAGTTAGCCATTGATTTATTTGGTAATAAAGAAGCA
CTGATTCGACTTGATATGAGTGAATATAGTGATACTACTGCTGTTTCTAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGACGATAATTCAAATACATTAACTGAAAAAGTACGACGCAATCCATATTCAGTCATTCTATTTGATGAAATTGAAA
AGGCTAATCCACAAATATTAACATTATTACTTCAAGTGATGGATGATGGTAATTTAACAGATGGTCAAGGTAACGTCATC
AACTTTAAAAACACAATCGTTATTTGTACGTCAAACGCTGGTTTTGGTAACGGTACAGACCAAGAATACGATGACATTAT
GCAAGAAATGAAAAAATTCTTCCGCCCTGAATTTCTTAACCGCTTCAATGGTATTGTGGAATTCTTACACCTAGATAAAG
AGTCACTACAAGAAATCATTAATTTATTGTTAGATGATGTCCAAGTAACATTAGATAAAAAAGGTATTACGATGAATGTC
TCTCAAGATGCAAAAGATTGGTTAATTGAAGAGGGATATGATGAAGAGTTAGGCGCACGCCCATTAAGACGTATTGTTGA
ACAACAAGTGCGTGACAAAATAACAGATTATTATTTAGATCATACAGACGTTAAACATGTGGATTTAGATATCGAAGACA
ATGAATTAGTCGTCAAAGGTAAATCATGA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• AAA lid domain (AAA_lid_9) (264-363)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	47.434	91.595	0.434
clpE	Streptococcus pneumoniae Rx1	47.002	87.892	0.413
clpE	Streptococcus pneumoniae D39	47.002	87.892	0.413
clpE	Streptococcus pneumoniae R6	47.002	87.892	0.413
clpE	Streptococcus pneumoniae TIGR4	47.002	87.892	0.413
clpC	Lactococcus lactis subsp. cremoris KW2	45.886	90.028	0.413
clpC	Bacillus subtilis subsp. subtilis str. 168	44.19	93.162	0.412
clpC	Streptococcus thermophilus LMD-9	44.8	89.031	0.399
clpC	Streptococcus thermophilus LMG 18311	44.64	89.031	0.397
clpC	Streptococcus pneumoniae TIGR4	43.61	89.174	0.389
clpC	Streptococcus pneumoniae Rx1	43.78	88.177	0.386
clpC	Streptococcus pneumoniae D39	43.78	88.177	0.386
clpC	Streptococcus mutans UA159	43.902	87.607	0.385
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.215	88.746	0.375