Detailed information NTG0620552

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: NW963_RS13180
• Genome accession: NZ_CP102972
• Coordinates: 2635993..2638098 (+)
• Length: 701 a.a.
• NCBI ID: WP_258412344.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain 05-RR-90
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2630993..2643098

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NW963_RS13160 (NW963_13155)	-	2631274..2632554 (-)	1281	WP_001180324.1	hydroxymethylglutaryl-CoA reductase, degradative	-
NW963_RS13165 (NW963_13160)	-	2632808..2633974 (+)	1167	WP_258412342.1	hydroxymethylglutaryl-CoA synthase	-
NW963_RS13170 (NW963_13165)	sey	2634196..2634861 (-)	666	WP_000644944.1	staphylococcal enterotoxin type Y	-
NW963_RS13175 (NW963_13170)	-	2635063..2635584 (-)	522	WP_258412343.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
NW963_RS13180 (NW963_13175)	clpE	2635993..2638098 (+)	2106	WP_258412344.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
NW963_RS13185 (NW963_13180)	-	2638160..2638330 (-)	171	WP_000111118.1	FeoB-associated Cys-rich membrane protein	-
NW963_RS13190 (NW963_13185)	feoB	2638343..2640337 (-)	1995	WP_258412345.1	ferrous iron transport protein B	-
NW963_RS13195 (NW963_13190)	-	2640349..2640576 (-)	228	WP_000932073.1	ferrous iron transport protein A	-

Sequence

Protein

• Length: 701 a.a.
• Molecular weight: 77952.29 Da
• Isoelectric Point: 4.5679

>NTDB_id=620552 NW963_RS13180 WP_258412344.1 2635993..2638098(+) (clpE) [Staphylococcus aureus strain 05-RR-90]
MNNDFFNSDFDSIFRRMMQDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSAQAFQQAAQRQQGQQDGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISV
DISSLEAGTQYRGAFEENIQKLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGNDAEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK

Nucleotide

• Length: 2106 bp

>NTDB_id=620552 NW963_RS13180 WP_258412344.1 2635993..2638098(+) (clpE) [Staphylococcus aureus strain 05-RR-90]
ATGAATAACGATTTTTTCAATAGCGACTTTGATTCAATTTTTCGAAGAATGATGCAAGATATGCAAGGTTCAAATCAAGT
CGGTAACAAAAAGTACTATATTAATGGTAAAGAAGTTTCACCTGAAGAACTAGCGCAACTCACACAACAAGGTGGCAATC
ACTCTGCTGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACAAAGACAACAAGGGCAACAAGATGGCAACGGCAATTAT
TTAGAACAAATTGGTCGTAACCTTACGCAAGAAGCACGTGACGGTTTATTAGATCCAGTCATTGGTCGTGATAAAGAAAT
TCAAGAAACTGCTGAAGTCTTAAGTAGACGAACTAAAAACAATCCTATATTAGTTGGAGAAGCTGGTGTTGGTAAAACTG
CGATTGTTGAAGGTTTAGCACAGGCAATCGTTGAAGGAAATGTACCAGCAGCAATCAAAGACAAAGAAATTATTTCTGTA
GATATTTCATCATTAGAAGCTGGAACGCAATATCGTGGTGCTTTTGAAGAAAATATTCAAAAATTAATCGAAGGTGTTAA
ATCTTCACAAAATGCCGTACTATTCTTTGATGAAATCCATCAAATTATCGGTTCAGGTGCCACAGGAAGTGATTCAGGTA
GCAAAGGGTTATCTGATATTTTGAAACCTGCATTAAGTCGTGGTGAGATTTCTATTATTGGTGCAACAACACAAGATGAA
TATCGAAACAATATTCTTAAAGATGCTGCATTAACGCGCAGATTTAATGAAGTACTTGTTAATGAACCAAGTGCTAAAGA
TACTGTGGAAATTTTAAAAGGTATTCGCGAAAAATTCGAAGAACACCATCAAGTAAAATTACCAGATGACGTATTAAAAG
CATGTGTTGACTTATCAATTCAATATATTCCACAACGATTATTACCAGATAAAGCAATCGATGTGTTAGATATTACAGCA
GCACATTTATCTGCGCAAAGTCCAGCTGTCGATAAAGTTGAAACTGAAAAACGAATTTCTGAATTAGAAAATGATAAACG
TAAAGCGGTAAGTGCTGAAGAATATAAAAAAGCTGACGACATTCAAAATGAAATTAAATCATTACAAGATAAATTAGAAA
ATAGTAATGGTGAACATACTGCTGTTGCTACAGTTCATGATATTTCAGATACTATTCAACGATTAACTGGTATTCCAGTT
TCTCAAATGGATGATAACGATATTGAACGTTTAAAAAATATTTCTAATCGTTTAAGAAGTAAAATCATAGGTCAAGATCA
AGCTGTAGAAATGGTTTCACGTGCAATTCGTCGTAATCGTGCTGGGTTTGATGACGGCAACCGTCCAATTGGCAGTTTCC
TATTTGTTGGCCCTACTGGTGTTGGTAAAACAGAGCTTGCTAAACAATTAGCAATTGATCTATTTGGTAATAAAGATGCA
CTGATTCGACTTGATATGAGTGAATATAGTGACACAACAGCTGTTTCAAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGATGACAATTCAAATACGTTAACTGAAAAAGTACGCCGTAATCCATACTCAGTCATTCTATTTGATGAAATCGAAA
AAGCAAATCCACAAATTTTAACATTGTTATTACAAGTAATGGATGATGGTAATTTGACTGATGGTCAAGGTAATGTCATC
AACTTTAAAAATACAATTATTATTTGTACATCAAATGCTGGCTTTGGCAATGGCAATGACGCTGAAGAAAAAGATATTAT
GCACGAAATGAAAAAATTCTTCCGCCCTGAATTCCTTAACCGCTTCAACGGCATCGTTGAATTCTTACATTTAGATAAAG
ATGCATTGCAAGATATCGTCAACTTATTATTAGACGATGTACAAGTTACATTAGACAAAAAAGGTATTACGATGGACGTT
TCTCAAGATGCGAAAGATTGGTTAATTGAAGAAGGCTATGATGAAGAATTAGGTGCACGTCCATTAAGACGTATTGTTGA
ACAGCAAGTACGTGACAAAATTACAGATTACTATTTAGATCATACAGACGTTAAACATGTGGATATAGATGTTGAGGATA
ACGAATTAGTCGTAAAAGGTAAATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (264-363)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	48.834	91.726	0.448
clpC	Lactococcus lactis subsp. cremoris KW2	44.993	95.435	0.429
clpE	Streptococcus pneumoniae Rx1	48.298	88.017	0.425
clpE	Streptococcus pneumoniae D39	48.298	88.017	0.425
clpE	Streptococcus pneumoniae R6	48.298	88.017	0.425
clpE	Streptococcus pneumoniae TIGR4	48.298	88.017	0.425
clpC	Bacillus subtilis subsp. subtilis str. 168	44.495	93.295	0.415
clpC	Streptococcus thermophilus LMD-9	44.201	91.013	0.402
clpC	Streptococcus thermophilus LMG 18311	43.887	91.013	0.399
clpC	Streptococcus pneumoniae Rx1	44.175	88.16	0.389
clpC	Streptococcus pneumoniae D39	44.175	88.16	0.389
clpC	Streptococcus pneumoniae TIGR4	44.175	88.16	0.389
clpC	Streptococcus mutans UA159	43.577	87.732	0.382
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.294	92.582	0.382