Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   NW965_RS04375 Genome accession   NZ_CP102968
Coordinates   925819..926535 (+) Length   238 a.a.
NCBI ID   WP_031906209.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 13-G-52     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 920819..931535
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NW965_RS04350 (NW965_04345) - 920899..921879 (+) 981 WP_234718849.1 dipeptide ABC transporter ATP-binding protein -
  NW965_RS04355 (NW965_04350) opp4B 921872..922834 (+) 963 WP_000239820.1 oligopeptide ABC transporter permease -
  NW965_RS04360 (NW965_04355) opp4C 922846..923727 (+) 882 WP_001180280.1 oligopeptide ABC transporter permease -
  NW965_RS04365 (NW965_04360) trpS 923769..924758 (-) 990 WP_000448934.1 tryptophan--tRNA ligase -
  NW965_RS04370 (NW965_04365) spxA 925053..925448 (+) 396 WP_000258003.1 transcriptional regulator SpxA -
  NW965_RS04375 (NW965_04370) mecA 925819..926535 (+) 717 WP_031906209.1 adaptor protein MecA Regulator
  NW965_RS04380 (NW965_04375) coiA 926656..927642 (+) 987 WP_103188523.1 competence protein CoiA family protein Machinery gene
  NW965_RS04385 (NW965_04380) pepF 927690..929498 (+) 1809 WP_000082725.1 oligoendopeptidase F Regulator
  NW965_RS04390 (NW965_04385) yjbH 929958..930764 (-) 807 WP_000896696.1 protease adaptor protein YjbH -
  NW965_RS04395 (NW965_04390) - 930787..931152 (-) 366 WP_000214068.1 truncated hemoglobin YjbI -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 28184.11 Da        Isoelectric Point: 4.1812

>NTDB_id=620224 NW965_RS04375 WP_031906209.1 925819..926535(+) (mecA) [Staphylococcus aureus strain 13-G-52]
MRIERVDDTTVKLFITYSDIEARGFSREDLWTNRKRGEEFFWSMMDEINEEEDFVVEGPLWIQVHAFEKGVEVTISKSKN
EDMMNMSDDATDQFDEQVQELLAQTLEGEDQLEELFEQRTKEKEAQGSKRQKSSARKNTRTIIVKFNDLEDVINYAYHSN
PITTEFEDLLYMVDGTYYYAVHFDSHVDQEVINDSYSQLLEFAYPTDRTEVYLNDYAKIIMSHNVTAQVRRYFPETTE

Nucleotide


Download         Length: 717 bp        

>NTDB_id=620224 NW965_RS04375 WP_031906209.1 925819..926535(+) (mecA) [Staphylococcus aureus strain 13-G-52]
ATGAGAATAGAACGAGTAGATGATACAACTGTAAAATTGTTTATAACATATAGCGATATCGAGGCCCGTGGATTTAGTCG
TGAAGATTTATGGACAAATCGCAAACGTGGCGAAGAATTCTTTTGGTCAATGATGGATGAAATTAACGAAGAAGAAGATT
TTGTTGTAGAAGGTCCATTATGGATTCAAGTACATGCCTTTGAAAAAGGTGTCGAAGTCACAATTTCTAAATCTAAAAAT
GAAGATATGATGAATATGTCTGATGATGCAACTGATCAATTTGATGAACAAGTTCAAGAATTGTTAGCTCAAACATTAGA
AGGTGAAGATCAATTAGAAGAATTATTCGAGCAACGAACAAAAGAAAAAGAAGCTCAAGGTTCTAAACGTCAAAAGTCTT
CAGCACGTAAAAATACAAGAACAATCATTGTGAAATTTAACGATTTAGAAGATGTTATTAATTATGCATATCATAGCAAT
CCAATAACTACAGAGTTTGAAGATTTGTTATATATGGTTGATGGTACTTATTATTATGCTGTACATTTTGATAGTCATGT
TGATCAAGAAGTCATTAATGATAGTTACAGTCAATTGCTTGAATTTGCTTATCCAACAGACAGAACAGAAGTTTATTTAA
ATGACTATGCTAAAATAATTATGAGTCATAACGTAACAGCTCAAGTTCGACGTTATTTTCCAGAGACAACTGAATAA

Domains

Predicted by InterProScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

37.712

99.16

0.374