Detailed information NTG0619666

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: NW979_RS12480
• Genome accession: NZ_CP102959
• Coordinates: 2557644..2559752 (+)
• Length: 702 a.a.
• NCBI ID: WP_258413558.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain 12-G-51
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2552644..2564752

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NW979_RS12460 (NW979_12460)	-	2552972..2554249 (-)	1278	WP_258413555.1	hydroxymethylglutaryl-CoA reductase, degradative	-
NW979_RS12465 (NW979_12465)	-	2554504..2555670 (+)	1167	WP_000151980.1	hydroxymethylglutaryl-CoA synthase	-
NW979_RS12470 (NW979_12470)	sey	2555893..2556558 (-)	666	WP_258413556.1	staphylococcal enterotoxin type Y	-
NW979_RS12475 (NW979_12475)	-	2556760..2557281 (-)	522	WP_258413557.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
NW979_RS12480 (NW979_12480)	clpE	2557644..2559752 (+)	2109	WP_258413558.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
NW979_RS12485 (NW979_12485)	-	2559819..2559989 (-)	171	WP_000111116.1	FeoB-associated Cys-rich membrane protein	-
NW979_RS12490 (NW979_12490)	feoB	2560002..2561996 (-)	1995	WP_258413559.1	ferrous iron transport protein B	-
NW979_RS12495 (NW979_12495)	-	2562008..2562235 (-)	228	WP_000932073.1	ferrous iron transport protein A	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 78112.61 Da
• Isoelectric Point: 4.6163

>NTDB_id=619666 NW979_RS12480 WP_258413558.1 2557644..2559752(+) (clpE) [Staphylococcus aureus strain 12-G-51]
MNNNFFNSDFDSILRRMMQDMQSSNQTSNKKYYINGKEVSPEELAQFTQQGGNHSVEQSAQAFQQAALRQQGQQSGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISI
DISSLEAGTQYRGAFEENIQKLVEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNIMKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDEVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQVKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDANDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGTDQEYDDIMQEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMNV
SQDAKDWLIEEGYDEDLGARPLRRIVEQQVRDKITDYYLDHTDVKHVDLDIEDNELVVKGKS

Nucleotide

• Length: 2109 bp

>NTDB_id=619666 NW979_RS12480 WP_258413558.1 2557644..2559752(+) (clpE) [Staphylococcus aureus strain 12-G-51]
ATGAATAACAATTTTTTCAATAGTGACTTCGATTCTATTTTACGAAGAATGATGCAAGACATGCAAAGCTCAAATCAGAC
TAGTAACAAGAAATACTATATTAATGGTAAAGAAGTTTCACCGGAAGAATTAGCACAATTTACGCAACAGGGTGGTAATC
ATTCTGTCGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACTAAGACAACAAGGTCAACAAAGTGGCAATGGCAATTAT
TTAGAACAAATTGGTCGTAACTTAACGCAGGAGGCTCGTGACGGATTATTAGATCCAGTCATCGGTCGTGATAAAGAAAT
CCAAGAAACTGCAGAAGTCTTAAGTAGACGCACTAAAAACAATCCTATCCTAGTCGGAGAAGCTGGGGTTGGTAAAACTG
CGATTGTCGAAGGTTTAGCGCAAGCAATCGTTGAAGGGAACGTACCTGCAGCAATCAAAGATAAAGAAATTATATCTATA
GATATTTCATCGCTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAACATCCAAAAGTTAGTTGAAGGCGTTAA
ATCATCACAAAATGCTGTGCTCTTCTTTGACGAAATTCACCAAATCATCGGTTCCGGTGCAACTGGAAGTGATTCCGGTA
GTAAAGGGTTATCTGATATTTTAAAACCAGCATTAAGTCGTGGTGAAATTTCAATTATAGGTGCAACGACTCAAGATGAA
TACCGCAATAATATCATGAAAGACGCTGCATTAACACGTCGTTTTAACGAGGTGCTGGTTAACGAACCAAGCGCAAAAGA
TACTGTTGAAATTTTAAAAGGTATTCGCGAAAAATTCGAAGAACACCATCAAGTAAAATTACCAGACGAGGTATTAAAAG
CATGTGTTGACTTATCAATTCAATATATTCCACAACGATTATTACCAGATAAAGCAATCGATGTGTTAGATATTACAGCA
GCACATTTATCTGCGCAAAGTCCAGCTGTCGATAAAGTTGAAACTGAAAAACGAATTTCTGAATTAGAAAATGATAAACG
TAAAGCGGTAAGTGCTGAAGAATATAAAAAAGCTGACGACATTCAAAATGAAATCAAATCATTACAAGTTAAATTAGAAA
ACAGTAATGGTGAACATACTGCAGTAGCAACGGTGCATGATATTTCTGATACCATTCAACGATTAACTGGTATTCCTGTA
TCTCAAATGGATGCCAATGACATTGAACGTTTAAAAAATATTTCTAATCGTTTAAGAAGTAAAATCATCGGTCAAGATCA
AGCTGTAGAAATGGTTTCTCGTGCAATTCGCCGTAATCGTGCTGGGTTTGATGACGGCAACCGTCCAATTGGCAGTTTCC
TATTTGTTGGCCCTACTGGTGTTGGTAAAACAGAGCTTGCTAAACAATTAGCAATTGATCTATTTGGTAATAAAGATGCA
CTGATCCGACTTGATATGAGTGAATATAGTGACACAACAGCTGTTTCAAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGATGACAATTCAAATACGTTAACTGAAAAAGTACGCCGTAATCCATATTCAGTCATTCTATTTGATGAAATCGAAA
AAGCAAATCCACAAATTTTAACATTGTTATTACAAGTAATGGATGATGGTAATTTGACTGATGGTCAAGGTAATGTCATC
AACTTTAAAAATACAATTATTATTTGTACATCAAATGCTGGCTTTGGTAACGGTACAGACCAAGAATACGATGACATTAT
GCAAGAAATGAAAAAATTCTTCCGCCCTGAATTCCTTAACCGCTTCAACGGCATCGTTGAATTCTTACATTTAGATAAAG
ATGCATTACAAGATATCGTCAACTTATTATTAGACGATGTCCAAGTAACATTAGATAAAAAAGGTATTACGATGAATGTC
TCTCAAGATGCAAAAGATTGGTTAATTGAAGAAGGTTATGATGAAGACTTAGGCGCACGCCCATTAAGACGTATTGTTGA
ACAGCAAGTACGTGACAAAATTACAGATTACTATTTAGATCATACTGACGTTAAACATGTGGATTTAGATATCGAGGACA
ATGAATTAGTCGTCAAAGGTAAATCATGA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

• AAA lid domain (AAA_lid_9) (264-363)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	48.989	91.595	0.449
clpE	Streptococcus pneumoniae Rx1	47.967	87.607	0.42
clpE	Streptococcus pneumoniae D39	47.967	87.607	0.42
clpE	Streptococcus pneumoniae R6	47.967	87.607	0.42
clpE	Streptococcus pneumoniae TIGR4	47.967	87.607	0.42
clpC	Lactococcus lactis subsp. cremoris KW2	46.519	90.028	0.419
clpC	Bacillus subtilis subsp. subtilis str. 168	44.104	93.02	0.41
clpC	Streptococcus thermophilus LMD-9	44.64	89.031	0.397
clpC	Streptococcus thermophilus LMG 18311	44.32	89.031	0.395
clpC	Streptococcus pneumoniae TIGR4	43.499	88.746	0.386
clpC	Streptococcus pneumoniae Rx1	43.499	88.746	0.386
clpC	Streptococcus pneumoniae D39	43.499	88.746	0.386
clpC	Streptococcus mutans UA159	43.415	87.607	0.38
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.788	88.889	0.38