Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   NWO26_RS06430 Genome accession   NZ_CP102797
Coordinates   1262934..1263227 (-) Length   97 a.a.
NCBI ID   WP_011226625.1    Uniprot ID   Q5M2G2
Organism   Streptococcus thermophilus strain ST057-1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1257934..1268227
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NWO26_RS06390 - 1258335..1258778 (-) 444 WP_113870473.1 CAAX protease -
  NWO26_RS06395 - 1258852..1259190 (-) 339 WP_224103197.1 CPBP family intramembrane glutamic endopeptidase -
  NWO26_RS06400 - 1259234..1259509 (-) 276 WP_011681681.1 hypothetical protein -
  NWO26_RS06405 - 1259521..1259719 (-) 199 Protein_1263 helix-turn-helix transcriptional regulator -
  NWO26_RS06410 - 1259968..1261161 (-) 1194 WP_014608740.1 acetate kinase -
  NWO26_RS06415 comGH 1261217..1262173 (-) 957 WP_011681684.1 class I SAM-dependent methyltransferase Machinery gene
  NWO26_RS06420 comGG 1262218..1262535 (-) 318 WP_011681685.1 competence type IV pilus minor pilin ComGG Machinery gene
  NWO26_RS06425 comGF 1262513..1262950 (-) 438 WP_011681686.1 competence type IV pilus minor pilin ComGF Machinery gene
  NWO26_RS06430 comGE 1262934..1263227 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  NWO26_RS06435 comGD 1263199..1263627 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  NWO26_RS06440 comGC 1263587..1263913 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  NWO26_RS06445 comGB 1263910..1265010 (-) 1101 WP_120764773.1 competence type IV pilus assembly protein ComGB Machinery gene
  NWO26_RS06450 comGA/cglA/cilD 1264892..1265833 (-) 942 WP_014608745.1 competence type IV pilus ATPase ComGA Machinery gene
  NWO26_RS06455 - 1265914..1266276 (-) 363 WP_014608746.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.74 Da        Isoelectric Point: 10.4561

>NTDB_id=618311 NWO26_RS06430 WP_011226625.1 1262934..1263227(-) (comGE) [Streptococcus thermophilus strain ST057-1]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=618311 NWO26_RS06430 WP_011226625.1 1262934..1263227(-) (comGE) [Streptococcus thermophilus strain ST057-1]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361