Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   LIS80_RS06255 Genome accession   NZ_CP085413
Coordinates   1241191..1241874 (+) Length   227 a.a.
NCBI ID   WP_000350710.1    Uniprot ID   Q81TR3
Organism   Bacillus paranthracis strain KF11     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1236191..1246874
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LIS80_RS06235 (LIS80_06235) - 1237261..1238907 (+) 1647 WP_000728616.1 peptide ABC transporter substrate-binding protein -
  LIS80_RS06240 (LIS80_06240) - 1238936..1239139 (-) 204 WP_000559978.1 hypothetical protein -
  LIS80_RS06245 (LIS80_06245) spx 1239732..1240127 (+) 396 WP_000258267.1 transcriptional regulator Spx -
  LIS80_RS06250 (LIS80_06250) - 1240177..1240851 (-) 675 WP_000362603.1 TerC family protein -
  LIS80_RS06255 (LIS80_06255) mecA 1241191..1241874 (+) 684 WP_000350710.1 adaptor protein MecA Regulator
  LIS80_RS06260 (LIS80_06260) - 1241947..1243491 (+) 1545 WP_000799204.1 cardiolipin synthase -
  LIS80_RS06265 (LIS80_06265) - 1243572..1244816 (+) 1245 WP_000612263.1 competence protein CoiA family protein -
  LIS80_RS06270 (LIS80_06270) pepF 1244867..1246693 (+) 1827 WP_000003390.1 oligoendopeptidase F Regulator

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 26966.00 Da        Isoelectric Point: 3.9822

>NTDB_id=617913 LIS80_RS06255 WP_000350710.1 1241191..1241874(+) (mecA) [Bacillus paranthracis strain KF11]
MDIERINDHTMKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPLWIQVQAVDKGIEVLVTKAEL
SKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQAGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELY
SFEDRYYVYVEFDEVLHDEEEIDRILSIVLEYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT

Nucleotide


Download         Length: 684 bp        

>NTDB_id=617913 LIS80_RS06255 WP_000350710.1 1241191..1241874(+) (mecA) [Bacillus paranthracis strain KF11]
TTGGATATTGAAAGAATTAATGATCATACGATGAAATTTTTTATTACGTACATTGATATAGAGGACAGAGGCTTTAATCG
TGAGGAAATTTGGTATGACCGCGAAAGAAGCGAAGAGCTCTTTTGGGAAATGATGGACGAAGCTCGTGATCATGACGATT
TCTTTATTGATGGGCCGTTATGGATTCAAGTGCAAGCAGTCGATAAAGGGATTGAAGTACTTGTAACGAAAGCAGAACTT
TCAAAGGATGGACAAAAGCTAGAACTACCAATAGGTGTAGATAAAATTATAGACATTCCTCTAGATGAAGGTATTGAATC
ATTATTCCAGCAAGAATTAGTGGAAGAGGTAGAGGAACAAGCAGGTACAAACTTTAACGAAGATGGTACGTTTGGCTTTT
TAATTAAGTTTAATGATTTTGAAGATGTCATTTCATTAAGTCATCGTCTTATCTTTGAAGATATAAAAGATGAGCTGTAT
TCATTTGAGGACCGCTATTATGTATATGTGGAATTCGATGAAGTGCTACATGATGAAGAAGAAATTGATCGCATTTTAAG
CATTGTTTTAGAATACGGGGAAGAATCAACTTTAACAATTCATCGTGTAAGTGAGTATGGGAAACAAATTGTGAAAGAGC
ATGCGCTTGAAACAATTCGCAATAATTTTCCTGCTAAAACGTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q81TR3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

56.14

100

0.564