Detailed information NTG0617878

Bioinformatically predicted

Overview

• Name: pilA
• Type: Machinery gene
• Locus tag: NWE23_RS05160
• Genome accession: NZ_CP102746
• Coordinates: 1042691..1043965 (-)
• Length: 424 a.a.
• NCBI ID: WP_012775180.1
• Uniprot ID: A0A0H3MUX4
• Organism: Streptococcus suis strain Transconjugant cAKJ47-2
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1037691..1048965

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NWE23_RS05130 (NWE23_05140)	-	1037803..1037949 (+)	147	WP_012027144.1	SPJ_0845 family protein	-
NWE23_RS05135 (NWE23_05145)	-	1037951..1038856 (+)	906	WP_012027145.1	permease	-
NWE23_RS05140 (NWE23_05150)	-	1038853..1039668 (+)	816	WP_012027146.1	TIGR03943 family protein	-
NWE23_RS05145 (NWE23_05155)	zwf	1039747..1041234 (+)	1488	WP_012027147.1	glucose-6-phosphate dehydrogenase	-
NWE23_RS05150 (NWE23_05160)	-	1041434..1042108 (+)	675	WP_012027148.1	DNA alkylation repair protein	-
NWE23_RS05155 (NWE23_05165)	-	1042110..1042667 (+)	558	WP_012027149.1	GNAT family N-acetyltransferase	-
NWE23_RS05160 (NWE23_05170)	pilA	1042691..1043965 (-)	1275	WP_012775180.1	signal recognition particle-docking protein FtsY	Machinery gene
NWE23_RS05165 (NWE23_05175)	-	1043967..1044779 (-)	813	WP_002936036.1	Cof-type HAD-IIB family hydrolase	-
NWE23_RS05170 (NWE23_05180)	-	1044769..1045578 (-)	810	WP_012027151.1	Cof-type HAD-IIB family hydrolase	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 47099.51 Da
• Isoelectric Point: 4.4431

>NTDB_id=617878 NWE23_RS05160 WP_012775180.1 1042691..1043965(-) (pilA) [Streptococcus suis strain Transconjugant cAKJ47-2]
MGLFDRLFGQKKQEEQVALVEEVEREQSASSEDTVTTEVESATQEMEKFQSEVAETELTAEQEAQKQRTLDMMAQYYAAK
EAAAARVKEAQEQGFDPAIQTKVKEEPVEEVAPVGQESEQDKYQRTLKKTRTGFGARLNEFFANFRSVDEEFFEELEEML
ILSDVGVQVASTLTEELRYEAKLQNAKKIDELRRVIIEKLVDIYEKDGQFSEQINFQDDLTVMLFVGVNGVGKTTSIGKL
AYKYKQAGKKVMLVAADTFRAGAVAQLVEWGRRVDVPVVTGPEKSDPASVVFDGVKRAVAEGVDILMIDTAGRLQNKENL
MAELEKIGRIIKRTLPDAPHETLLALDASTGQNALSQAKEFAKITPLTGLVLTKLDGTAKGGVVLAIRQELDIPVKLIGF
GEKIDDIGEFKSEEFMRGLLEGLV

Nucleotide

• Length: 1275 bp

>NTDB_id=617878 NWE23_RS05160 WP_012775180.1 1042691..1043965(-) (pilA) [Streptococcus suis strain Transconjugant cAKJ47-2]
ATGGGATTATTTGATCGATTATTTGGACAAAAAAAACAAGAGGAGCAAGTCGCTCTTGTTGAAGAAGTGGAAAGGGAGCA
GTCGGCTTCTAGCGAAGATACAGTAACTACTGAAGTTGAGTCAGCTACTCAAGAAATGGAAAAGTTCCAGTCTGAAGTAG
CAGAGACTGAATTGACAGCCGAACAAGAAGCTCAGAAACAACGGACCTTAGACATGATGGCTCAATATTATGCAGCCAAA
GAAGCCGCTGCGGCTCGAGTGAAGGAAGCGCAGGAACAAGGCTTTGACCCTGCTATTCAAACCAAGGTCAAGGAAGAGCC
TGTTGAGGAAGTTGCTCCAGTAGGGCAAGAAAGTGAACAGGACAAGTACCAGCGTACCTTGAAAAAGACGCGTACAGGAT
TTGGGGCAAGGCTCAATGAATTCTTTGCCAATTTCCGTTCGGTTGATGAAGAATTTTTCGAAGAGTTGGAAGAAATGCTG
ATTTTGTCAGACGTAGGTGTGCAAGTTGCTTCTACGCTGACAGAGGAGCTCCGCTATGAAGCCAAGCTACAAAATGCCAA
GAAGATAGATGAACTCCGTCGTGTTATCATCGAAAAATTGGTGGATATTTACGAAAAAGACGGTCAATTCAGTGAGCAAA
TCAATTTCCAAGATGATTTGACAGTCATGCTCTTTGTCGGTGTCAACGGTGTTGGGAAGACGACGTCTATCGGTAAGTTA
GCCTACAAGTACAAGCAAGCTGGCAAGAAGGTCATGTTGGTCGCAGCGGACACCTTCCGTGCGGGTGCGGTAGCCCAGCT
GGTCGAGTGGGGTCGCCGTGTCGATGTGCCAGTAGTCACAGGACCTGAAAAGTCAGACCCAGCTAGTGTGGTTTTTGATG
GGGTAAAACGTGCCGTGGCAGAAGGCGTGGATATTCTCATGATTGATACAGCAGGTCGCTTGCAAAATAAAGAAAACCTC
ATGGCAGAGCTGGAAAAAATCGGTCGCATCATCAAACGGACCCTACCTGATGCACCGCATGAAACCCTCTTAGCACTGGA
TGCCTCCACAGGTCAAAACGCCCTCAGTCAAGCCAAGGAATTTGCAAAAATTACTCCATTGACTGGGCTAGTCTTGACCA
AGCTAGACGGTACAGCCAAGGGTGGTGTCGTTCTTGCCATCCGTCAGGAACTGGATATACCAGTTAAGCTAATTGGTTTC
GGTGAGAAAATCGATGACATCGGTGAATTCAAATCCGAAGAATTCATGCGTGGGCTATTGGAAGGATTGGTATAG

Domains

Predicted by InterProScan.

• SRP54-type protein, GTPase domain (SRP54) (221-420)

• SRP54-type protein, helical bundle domain (SRP54_N) (134-200)

3D structure

• AlphaFold DB: A0A0H3MUX4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilA	Neisseria gonorrhoeae MS11	36.322	100	0.373