Detailed information NTG0617540

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: NUT86_RS23760
• Genome accession: NZ_CP102609
• Coordinates: 5599438..5600562 (-)
• Length: 374 a.a.
• NCBI ID: WP_026170238.1
• Uniprot ID: A0A640THM3
• Organism: Streptomyces sp. G7(2002)
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 5594438..5605562

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NUT86_RS23740 (NUT86_23780)	-	5594616..5596298 (+)	1683	WP_274740599.1	GAF domain-containing protein	-
NUT86_RS23745 (NUT86_23785)	-	5596511..5597212 (-)	702	WP_109891726.1	response regulator transcription factor	-
NUT86_RS23750 (NUT86_23790)	-	5597495..5598829 (+)	1335	WP_274737490.1	globin domain-containing protein	-
NUT86_RS23755 (NUT86_23795)	-	5598911..5599414 (+)	504	WP_159486899.1	pyridoxamine 5'-phosphate oxidase family protein	-
NUT86_RS23760 (NUT86_23800)	disA	5599438..5600562 (-)	1125	WP_026170238.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
NUT86_RS23765 (NUT86_23805)	radA	5600688..5602100 (-)	1413	WP_018093005.1	DNA repair protein RadA	Machinery gene
NUT86_RS23770 (NUT86_23810)	-	5602345..5604096 (+)	1752	WP_159486897.1	sigma-70 family RNA polymerase sigma factor	-
NUT86_RS23775 (NUT86_23815)	-	5604148..5605020 (-)	873	WP_266450545.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40289.13 Da
• Isoelectric Point: 4.9306

>NTDB_id=617540 NUT86_RS23760 WP_026170238.1 5599438..5600562(-) (disA) [Streptomyces sp. G7(2002)]
MAANDRASTPGRSGGSSSTESLMRASLSAVAPGTALRDGLERILRGNTGGLIVLGFDKTVETMCTGGFVLDVEFTATRLR
ELCKLDGALVLDKDITKILRAGVQLVPDASIPTEETGTRHRTAQRVSIQAGFPVVSVSQSMRLIALYVDGERRVLEESAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLEELIA
GVEPERELVVRDYVPEPTAKRSRTVAEALAELDALSHTELLELPIVARALGYSGAPETLDSAVSPRGFRLLAKVPRLPGT
VIDRLVDHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=617540 NUT86_RS23760 WP_026170238.1 5599438..5600562(-) (disA) [Streptomyces sp. G7(2002)]
GTGGCAGCCAACGACCGGGCATCGACTCCCGGCAGGTCCGGTGGCAGTTCCTCCACCGAGAGCCTGATGCGCGCCTCACT
GAGCGCCGTCGCGCCCGGTACGGCCCTGCGCGACGGACTGGAACGCATCCTCCGCGGCAACACCGGCGGACTGATCGTGC
TGGGCTTCGACAAGACCGTCGAGACCATGTGCACCGGCGGATTCGTCCTCGACGTGGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGTGCGCTGGTCCTCGACAAGGACATCACCAAGATCCTGCGGGCCGGCGTCCAGCTGGTCCC
GGACGCCTCCATCCCGACGGAGGAGACCGGCACCCGCCACCGCACCGCCCAGCGCGTCTCCATCCAGGCCGGCTTCCCGG
TCGTCTCCGTCAGCCAGTCGATGCGCCTGATCGCCCTCTACGTCGACGGCGAGCGCCGCGTCCTGGAGGAGTCGGCCGCG
ATCCTCTCCCGCGCCAACCAGGCCCTGGCGACCCTGGAGCGCTACAAGCTCCGCCTGGACGAGGTCGCCGGCACCCTCTC
CGCCCTGGAGATCGAGGACTTGGTCACGGTCCGCGATGTCACCGCGGTCGCCCAGCGCCTGGAGATGGTCCGCCGGATCG
CCACCGAGATCGCCGAGTACGTCGTCGAGCTCGGCACGGACGGCCGGCTGCTCGCCCTCCAGCTGGAGGAGCTGATCGCC
GGCGTGGAGCCCGAGCGGGAGCTGGTCGTCCGCGACTACGTCCCCGAGCCGACCGCCAAGCGCTCCCGCACGGTCGCCGA
GGCGCTCGCCGAGCTGGACGCCCTCAGCCACACCGAGCTCCTCGAACTCCCCATCGTGGCCCGCGCGCTGGGCTACAGCG
GCGCCCCCGAGACCCTGGACTCCGCGGTCTCGCCGCGCGGTTTCCGCCTGCTGGCGAAGGTCCCCCGGCTGCCCGGCACG
GTCATCGACCGCCTCGTCGACCACTTCGGCGGCCTGCAGAAGCTCCTCGCGGCCAGCGTCGACGACCTCCAGACGGTCGA
CGGCGTCGGCGAGGCCCGCGCCCGCTCGGTCCGCGAGGGCCTGTCGCGGCTCGCGGAGTCGTCGATCCTGGAGCGGTACG
TCTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-296)

3D structure

• AlphaFold DB: A0A640THM3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.665	92.513	0.422