Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   LIT38_RS08280 Genome accession   NZ_CP085394
Coordinates   1603630..1605783 (-) Length   717 a.a.
NCBI ID   WP_243508229.1    Uniprot ID   -
Organism   Bacillus sp. CMF12     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1602129..1603485 1603630..1605783 flank 145


Gene organization within MGE regions


Location: 1602129..1605783
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LIT38_RS08275 (LIT38_08290) - 1602129..1603485 (+) 1357 Protein_1558 IS1182 family transposase -
  LIT38_RS08280 (LIT38_08295) clpC 1603630..1605783 (-) 2154 WP_243508229.1 ATP-dependent Clp protease ATP-binding subunit Regulator

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 79925.36 Da        Isoelectric Point: 5.2980

>NTDB_id=617508 LIT38_RS08280 WP_243508229.1 1603630..1605783(-) (clpC) [Bacillus sp. CMF12]
MLCQKCQTKQANVQLRLKLNGSERNLNLCHSCYQTEKQHSLTSFGPALSGFSGFGQMPLEDLFKKMAASQGNENYGLKEA
PGHNHGNGGFIDQFGRNLTQLAKAGLIDPVIGRDEEINRMIEILNRRSKNNPVLIGEPGVGKTAIAEGLAIKIAEGNAPK
KLQNKEVYLLDVASLVANTGIRGQFEERMKQLISELQTRKNIILFIDEIHLLVGAGSAEGSMDAGNILKPALARGELQVV
GATTLKEYRQIEKDPALERRFQPVQIEEPAANEAIEILMGLKQKYEDYHDVSFTEDAIKACVQLSSRYIQDRFLPDKAID
LMDEAGSKMNLQSGYIPAEDIEKQLKVISRQKELVLKEEKYEEAAKLREEELKLQQALNGDNKAERPVIEVSHIQEIIEK
KTGIPVGKLAEDEQEKMQNLEESLAEKVIGQAEAVRKVAKAIRRSRAGLKSKYRPIGSFLFVGPTGVGKTELTKTLAQEL
FGSKDSMIRLDMSEYMEKHSVSKIIGSPPGYVGHEEAGQLTEKVRRNPYSIILLDEIEKAHPDVQHMFLQILEDGRLTDS
QGRTVSFKDTVIIMTSNAGAGQKEIHVGFGAADAVMESNILESLGSFFKPEFLNRFDSIIEFKALEKEHLLKIVDLMLNE
LQETLNEQDIELTVTQEAKEKLAADGYHPAFGARPLRRIIQDELEDKIADFIIDHGGNSQLQADLENEIIVIKPLPQ

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=617508 LIT38_RS08280 WP_243508229.1 1603630..1605783(-) (clpC) [Bacillus sp. CMF12]
ATGCTTTGTCAAAAATGTCAAACAAAACAAGCAAATGTACAATTAAGACTGAAATTGAATGGAAGTGAACGAAATCTAAA
CCTTTGCCATAGCTGTTATCAAACTGAAAAGCAACATAGCCTTACTTCCTTTGGGCCTGCTTTGAGTGGTTTTTCAGGTT
TTGGCCAAATGCCTTTAGAGGATTTATTCAAGAAGATGGCTGCCTCTCAAGGAAATGAAAACTATGGTCTAAAAGAAGCG
CCGGGACACAATCATGGCAATGGCGGATTTATCGATCAATTCGGACGAAATCTTACACAGCTTGCCAAAGCCGGTTTAAT
TGACCCAGTCATCGGACGGGATGAAGAAATAAATCGTATGATTGAAATATTAAATAGAAGAAGCAAAAATAATCCGGTCT
TAATCGGTGAACCAGGAGTAGGTAAAACAGCTATTGCCGAAGGGCTAGCCATTAAGATTGCCGAGGGAAATGCACCAAAG
AAACTTCAAAATAAAGAAGTCTATTTGCTGGATGTGGCATCCCTGGTTGCAAACACAGGCATCCGCGGCCAATTCGAAGA
ACGCATGAAGCAGCTGATCTCGGAGCTTCAGACACGGAAGAATATTATTCTCTTTATAGATGAAATTCATTTGCTTGTTG
GAGCAGGCTCAGCCGAAGGATCAATGGATGCAGGCAATATTCTAAAGCCCGCCCTTGCACGGGGAGAGCTTCAAGTGGTC
GGAGCCACTACATTAAAAGAATACCGCCAAATTGAAAAAGATCCTGCATTGGAACGCAGATTCCAGCCTGTTCAAATAGA
AGAGCCTGCTGCAAATGAGGCAATTGAAATCTTGATGGGACTGAAACAAAAATACGAAGATTACCATGATGTTTCTTTTA
CTGAAGATGCCATTAAAGCATGTGTGCAGCTGTCAAGCCGCTATATTCAGGACCGGTTCCTTCCTGACAAAGCCATTGAT
TTAATGGATGAAGCAGGTTCTAAAATGAATCTTCAATCAGGATATATACCAGCAGAAGATATTGAAAAACAGCTGAAAGT
AATCAGCAGGCAAAAAGAACTTGTTTTAAAAGAAGAAAAATATGAAGAGGCTGCAAAACTCCGTGAAGAGGAACTAAAGC
TCCAGCAGGCACTAAACGGGGACAACAAGGCTGAACGGCCAGTTATTGAAGTTAGCCATATTCAGGAGATTATCGAAAAG
AAAACTGGGATTCCTGTCGGCAAATTAGCAGAAGATGAGCAGGAAAAAATGCAGAACCTTGAGGAAAGTCTTGCAGAAAA
AGTAATTGGACAGGCGGAAGCCGTGAGGAAAGTTGCAAAGGCAATTCGCCGAAGCCGTGCAGGACTTAAATCAAAGTACC
GCCCAATTGGCTCTTTTCTATTTGTCGGGCCAACAGGCGTCGGCAAGACTGAGCTGACCAAAACACTTGCCCAAGAGCTA
TTCGGCTCAAAAGACAGCATGATCAGGCTTGATATGAGTGAATATATGGAAAAACACAGCGTATCAAAAATTATCGGTTC
CCCTCCAGGATATGTGGGTCATGAAGAAGCCGGACAGCTTACTGAGAAGGTACGCAGAAACCCATACAGCATCATTCTGC
TTGATGAGATAGAAAAAGCACATCCAGATGTACAGCACATGTTCCTTCAAATACTGGAAGATGGACGCCTGACAGATAGC
CAGGGCCGCACTGTCAGCTTTAAAGATACAGTCATTATCATGACAAGCAATGCAGGAGCTGGGCAAAAGGAAATCCATGT
TGGTTTTGGCGCAGCTGACGCCGTCATGGAGTCAAACATTCTTGAATCGCTCGGCAGCTTCTTTAAGCCGGAATTCCTGA
ACCGCTTTGATAGCATTATTGAGTTTAAAGCTTTGGAAAAAGAGCATTTATTGAAAATTGTCGACTTAATGCTTAATGAG
CTTCAGGAAACATTAAATGAACAGGATATTGAATTGACTGTTACCCAGGAAGCCAAGGAGAAATTAGCAGCAGATGGATA
TCATCCTGCTTTTGGCGCACGGCCATTAAGAAGGATCATCCAGGATGAACTTGAAGACAAGATTGCTGATTTCATCATTG
ATCATGGCGGAAATAGCCAATTGCAGGCCGATCTCGAAAACGAAATAATTGTCATTAAGCCCCTGCCCCAATAA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(272-369)

ATPase family associated with various cellular activities (AAA) (AAA)

(133-262)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(625-695)

AAA domain (Cdc48 subfamily) (AAA_2)

(454-619)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

59.537

100

0.609
  clpE Streptococcus mutans UA159

56.157

100

0.579
  clpE Streptococcus pneumoniae D39

55.907

100

0.568
  clpE Streptococcus pneumoniae TIGR4

55.907

100

0.568
  clpE Streptococcus pneumoniae R6

55.907

100

0.568
  clpE Streptococcus pneumoniae Rx1

55.907

100

0.568
  clpC Bacillus subtilis subsp. subtilis str. 168

53.375

88.842

0.474
  clpC Streptococcus thermophilus LMD-9

45.736

89.958

0.411
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.419

86.471

0.41
  clpC Streptococcus thermophilus LMG 18311

45.3

90.516

0.41
  clpC Streptococcus mutans UA159

47.164

86.053

0.406
  clpC Streptococcus pneumoniae Rx1

46.591

85.914

0.4
  clpC Streptococcus pneumoniae D39

46.591

85.914

0.4
  clpC Streptococcus pneumoniae TIGR4

46.591

85.914

0.4