Detailed information    

insolico Bioinformatically predicted

Overview


Name   comW   Type   Regulator
Locus tag   MOP79_RS08525 Genome accession   NZ_CP102583
Coordinates   1677589..1677825 (+) Length   78 a.a.
NCBI ID   WP_000939545.1    Uniprot ID   A0A0H2ZMA7
Organism   Streptococcus pneumoniae strain D39Mega17545     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context


Location: 1672589..1682825
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MOP79_RS08495 - 1673065..1673712 (-) 648 WP_001824648.1 hypothetical protein -
  MOP79_RS08500 - 1673726..1674439 (-) 714 WP_000499433.1 YjjG family noncanonical pyrimidine nucleotidase -
  MOP79_RS08505 dhaM 1674897..1675277 (-) 381 Protein_1688 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  MOP79_RS10540 - 1675277..1675351 (-) 75 Protein_1689 dihydroxyacetone kinase subunit L -
  MOP79_RS08510 - 1675699..1676007 (-) 309 Protein_1690 histidine motif-containing protein -
  MOP79_RS08515 - 1676016..1676492 (+) 477 Protein_1691 transposase -
  MOP79_RS08520 - 1676527..1677323 (-) 797 Protein_1692 transposase -
  MOP79_RS08525 comW 1677589..1677825 (+) 237 WP_000939545.1 sigma(X)-activator ComW Regulator
  MOP79_RS08530 - 1678056..1679342 (+) 1287 WP_000205044.1 adenylosuccinate synthase -
  MOP79_RS08535 tadA 1679543..1680010 (+) 468 WP_000291874.1 tRNA adenosine(34) deaminase TadA -
  MOP79_RS08545 - 1680197..1680640 (+) 444 WP_000701992.1 dUTP diphosphatase -
  MOP79_RS08550 - 1680642..1681157 (+) 516 WP_000691236.1 histidine phosphatase family protein -
  MOP79_RS08555 radA 1681171..1682532 (+) 1362 WP_074017595.1 DNA repair protein RadA Machinery gene

Sequence


Protein


Download         Length: 78 a.a.        Molecular weight: 9658.13 Da        Isoelectric Point: 6.7051

>NTDB_id=617329 MOP79_RS08525 WP_000939545.1 1677589..1677825(+) (comW) [Streptococcus pneumoniae strain D39Mega17545]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=617329 MOP79_RS08525 WP_000939545.1 1677589..1677825(+) (comW) [Streptococcus pneumoniae strain D39Mega17545]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAAGGATTTTA
TTGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGGTTTATTTCTTGTTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A0H2ZMA7

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

100

100

1

  comW Streptococcus pneumoniae D39

100

100

1

  comW Streptococcus pneumoniae R6

100

100

1

  comW Streptococcus pneumoniae TIGR4

100

100

1

  comW Streptococcus mitis SK321

75.641

100

0.756

  comW Streptococcus mitis NCTC 12261

75.325

98.718

0.744