Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   LI754_RS11060 Genome accession   NZ_CP085320
Coordinates   2207143..2207859 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain CJFA-182     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2202143..2212859
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LI754_RS11030 - 2202362..2202988 (+) 627 WP_000522384.1 nitroreductase family protein -
  LI754_RS11035 - 2203349..2204134 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  LI754_RS14880 hld 2204731..2204811 (-) 81 WP_000046022.1 delta-hemolysin -
  LI754_RS11045 agrB 2205101..2205670 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  LI754_RS11050 agrD 2205667..2205807 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  LI754_RS11055 agrC 2205832..2207124 (+) 1293 WP_044290665.1 quorum-sensing sensor histidine kinase AgrC -
  LI754_RS11060 agrA 2207143..2207859 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  LI754_RS11065 - 2207931..2208040 (+) 110 Protein_2138 hypothetical protein -
  LI754_RS11070 - 2208228..2209187 (-) 960 WP_001253302.1 carbohydrate kinase family protein -
  LI754_RS11075 - 2209184..2210668 (-) 1485 WP_000141427.1 sucrose-6-phosphate hydrolase -
  LI754_RS11080 - 2210817..2211767 (-) 951 WP_000790329.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=617210 LI754_RS11060 WP_000688492.1 2207143..2207859(+) (agrA) [Staphylococcus aureus strain CJFA-182]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=617210 LI754_RS11060 WP_000688492.1 2207143..2207859(+) (agrA) [Staphylococcus aureus strain CJFA-182]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1