Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   LI911_RS13695 Genome accession   NZ_CP085318
Coordinates   2760066..2760782 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain CKFA-361     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2755066..2765782
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LI911_RS13675 - 2756158..2757108 (+) 951 WP_000790326.1 LacI family DNA-binding transcriptional regulator -
  LI911_RS13680 - 2757257..2758741 (+) 1485 WP_000141435.1 sucrose-6-phosphate hydrolase -
  LI911_RS13685 - 2758738..2759697 (+) 960 WP_001253302.1 carbohydrate kinase family protein -
  LI911_RS13690 - 2759885..2759994 (-) 110 Protein_2653 hypothetical protein -
  LI911_RS13695 agrA 2760066..2760782 (-) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  LI911_RS13700 agrC 2760801..2762093 (-) 1293 WP_001657119.1 quorum-sensing sensor histidine kinase AgrC -
  LI911_RS13705 agrD 2762118..2762258 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  LI911_RS13710 agrB 2762255..2762824 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  LI911_RS13715 hld 2763114..2763194 (+) 81 WP_000046022.1 delta-hemolysin -
  LI911_RS13720 - 2763794..2764579 (-) 786 WP_000867939.1 carbon-nitrogen family hydrolase -
  LI911_RS13725 - 2764940..2765566 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=617173 LI911_RS13695 WP_000688498.1 2760066..2760782(-) (agrA) [Staphylococcus aureus strain CKFA-361]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=617173 LI911_RS13695 WP_000688498.1 2760066..2760782(-) (agrA) [Staphylococcus aureus strain CKFA-361]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996