Detailed information NTG0617103

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: NUU05_RS02890
• Genome accession: NZ_CP102538
• Coordinates: 527067..529166 (+)
• Length: 699 a.a.
• NCBI ID: WP_011681535.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain TH-4
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 522067..534166

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NUU05_RS02860 (NUU05_02845)	yhbY	522172..522489 (+)	318	WP_002951701.1	ribosome assembly RNA-binding protein YhbY	-
NUU05_RS02865 (NUU05_02850)	-	522593..523225 (+)	633	WP_002951698.1	nicotinate-nucleotide adenylyltransferase	-
NUU05_RS02870 (NUU05_02855)	yqeK	523222..523812 (+)	591	WP_002951696.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
NUU05_RS02875 (NUU05_02860)	rsfS	523836..524189 (+)	354	WP_011227491.1	ribosome silencing factor	-
NUU05_RS02880 (NUU05_02865)	-	524514..525254 (+)	741	WP_277426406.1	class I SAM-dependent methyltransferase	-
NUU05_RS02885 (NUU05_02870)	-	525261..526352 (+)	1092	WP_011681536.1	nucleotidyltransferase	-
NUU05_RS02890 (NUU05_02875)	clpE	527067..529166 (+)	2100	WP_011681535.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
NUU05_RS02895 (NUU05_02880)	-	529584..529709 (+)	126	WP_011681534.1	hypothetical protein	-
NUU05_RS02900 (NUU05_02885)	-	529728..530363 (+)	636	WP_011681533.1	DUF4230 domain-containing protein	-
NUU05_RS02905 (NUU05_02890)	-	530433..531110 (+)	678	WP_011681532.1	hypothetical protein	-
NUU05_RS02910 (NUU05_02895)	-	531162..531461 (-)	300	WP_011681531.1	hypothetical protein	-
NUU05_RS02915 (NUU05_02900)	-	531458..531877 (-)	420	WP_011681530.1	HIT family protein	-
NUU05_RS02920 (NUU05_02905)	pptA	531942..532673 (+)	732	WP_002951673.1	ABC transporter ATP-binding protein	Regulator
NUU05_RS02925 (NUU05_02910)	pptB	532673..533707 (+)	1035	WP_024703983.1	ABC transporter permease	Regulator

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77200.11 Da
• Isoelectric Point: 4.8280

>NTDB_id=617103 NUU05_RS02890 WP_011681535.1 527067..529166(+) (clpE) [Streptococcus thermophilus strain TH-4]
MNNNFNNMDDLFNQLMGNMGGFRSESRRYMINGREVTPEEFAIYRQTGKLPGNQGEAVNPTQQHGPKQDGILAKLGRNLT
QEAREGKLDPVIGRNKEIQETAEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKDKEIISIDISALEAGT
QYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGEITVIGATTQDEYRNTILKNA
ALARRFNEVKVNAPSPEDTFKILQGIRDLYEKHHNVILPDEVLKAAVDFSVQYIPQRSLPDKAIDLLDMTAAHLAAQHPV
TDVNAVEREIEEEKAKQEAAVAKEDYEAALNSKIRIEKLEKEIANHAKDRKVTATVNDVAESVERMTGIPVSQMGASDIE
RLKDMGNRLQAKVIGQDKAVEAVARSIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDLFGTKDAIIRLDMSEY
SDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIA
TSNAGFGYESNSTEDADKPELMDRLKPYFRPEFLNRFDAVIEFSHLDKEDLSKIVDLMLNEVNKTLSKKGIDLAVSEAAK
AYMTEEGYDEVMGARPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide

• Length: 2100 bp

>NTDB_id=617103 NUU05_RS02890 WP_011681535.1 527067..529166(+) (clpE) [Streptococcus thermophilus strain TH-4]
ATGAACAACAACTTTAATAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTTCCGTTCAGAAAGCCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCAATTTACCGTCAAACAGGTAAATTGCCTGGTAATC
AAGGTGAAGCAGTGAACCCAACACAACAACACGGACCTAAACAAGATGGTATTCTTGCTAAGCTTGGTCGTAACTTGACT
CAAGAAGCTCGTGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAACTGCCGAAATTTTGTCTCG
TCGTACTAAGAATAACCCAGTCCTTGTCGGTGATGCTGGGGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCACAAGCCA
TCGTTAATGGTGATGTCCCAGCTGCTATCAAGGATAAAGAAATCATCTCAATTGATATTTCTGCACTTGAAGCTGGTACT
CAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGAAACATTATCCTCTTCTT
CGATGAAATTCATCAAATTCTTGGTGCCGGAAGCACTGGCGATGGTCAAGGTTCTAAAGGTCTGGCTGATATCTTGAAAC
CTGCTCTTTCACGTGGTGAAATAACAGTTATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAGAATGCT
GCCCTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTCCTGAAGATACCTTCAAGATTCTTCAAGGTATTCG
TGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGAAGTCTTGAAAGCAGCGGTTGATTTTTCAGTACAATACA
TTCCACAACGTAGCTTGCCAGATAAGGCTATTGACCTTTTGGACATGACAGCAGCTCACTTGGCAGCACAACATCCAGTA
ACTGATGTCAATGCTGTTGAACGTGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGTTGCTAAAGAAGATTACGA
AGCAGCTCTAAATTCTAAGATTCGTATTGAAAAACTTGAAAAGGAAATTGCTAACCATGCAAAAGATCGCAAGGTGACTG
CGACTGTAAACGATGTGGCTGAATCCGTAGAACGTATGACTGGTATTCCAGTATCTCAAATGGGTGCATCGGATATCGAA
CGTTTGAAAGATATGGGTAACCGTTTGCAAGCTAAGGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGGCACGTTCCAT
CCGTCGTAATCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTGTTGGTA
AAACTGAGTTGGCTAAACAATTGGCCCTTGATTTGTTCGGTACCAAAGATGCTATCATCCGTTTGGACATGTCAGAATAC
AGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGATAATAGTAATACCTTGAC
AGAACGTGTTCGTCGTAACCCTTATTCAATCATCCTTCTTGATGAAATTGAAAAGGCAGACCCTCAAGTTATCACCCTTC
TCCTCCAAGTTTTGGATGATGGTCGTTTGACTGATGGTCAAGGTAATACTGTAAACTTCAAGAACACAGTCATTATCGCA
ACTTCAAACGCTGGCTTTGGTTACGAATCTAACTCGACAGAAGATGCTGATAAACCAGAACTCATGGATCGTTTGAAACC
TTACTTCCGTCCTGAATTCCTTAACCGTTTCGACGCAGTTATTGAGTTCTCACACTTAGATAAGGAGGACCTTTCTAAGA
TTGTCGATCTTATGTTGAATGAAGTTAACAAGACTCTTTCTAAGAAAGGCATTGACTTGGCAGTTAGCGAAGCTGCTAAA
GCCTATATGACAGAAGAAGGCTATGATGAAGTTATGGGTGCTCGTCCACTCCGTCGTGTGGTTGAACAACAAATCCGTGA
CAAAGTCACAGACTTCCACTTGGATAACCTTGATGCAAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTAGTTATCA
AAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (606-676)

• AAA lid domain (AAA_lid_9) (255-349)

• ATPase family associated with various cellular activities (AAA) (AAA) (114-246)

• AAA domain (Cdc48 subfamily) (AAA_2) (439-599)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	46.924	100	0.469
clpC	Lactococcus lactis subsp. cremoris KW2	49.219	91.559	0.451
clpE	Streptococcus pneumoniae D39	48.657	90.558	0.441
clpE	Streptococcus pneumoniae R6	48.657	90.558	0.441
clpE	Streptococcus pneumoniae Rx1	48.657	90.558	0.441
clpE	Streptococcus pneumoniae TIGR4	48.657	90.558	0.441
clpC	Bacillus subtilis subsp. subtilis str. 168	45.975	92.418	0.425
clpC	Streptococcus thermophilus LMD-9	43.26	91.273	0.395
clpC	Streptococcus thermophilus LMG 18311	43.103	91.273	0.393
clpC	Streptococcus pneumoniae TIGR4	43.499	89.127	0.388
clpC	Streptococcus pneumoniae Rx1	43.499	89.127	0.388
clpC	Streptococcus pneumoniae D39	43.499	89.127	0.388
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.598	88.269	0.385
clpC	Streptococcus mutans UA159	43.156	88.841	0.383