Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   EKM74_RS12205 Genome accession   NZ_AP019306
Coordinates   2302704..2303378 (+) Length   224 a.a.
NCBI ID   WP_001166500.1    Uniprot ID   Q99VW2
Organism   Staphylococcus aureus strain TUM9463     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2297704..2308378
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EKM74_RS12175 - 2297919..2298986 (+) 1068 WP_000980137.1 membrane protein -
  EKM74_RS12180 - 2299137..2300180 (+) 1044 WP_001030772.1 alpha/beta hydrolase -
  EKM74_RS12190 - 2300509..2300937 (+) 429 WP_000198504.1 hypothetical protein -
  EKM74_RS12195 - 2301146..2301652 (-) 507 WP_000940129.1 GNAT family N-acetyltransferase -
  EKM74_RS12200 graX 2301765..2302688 (+) 924 WP_000802955.1 auxiliary protein GraX/ApsX -
  EKM74_RS12205 braR 2302704..2303378 (+) 675 WP_001166500.1 response regulator transcription factor GraR/ApsR Regulator
  EKM74_RS12210 graS 2303371..2304411 (+) 1041 WP_001061264.1 histidine kinase GraS/ApsS -
  EKM74_RS12215 vraF 2304555..2305316 (+) 762 WP_000985996.1 ABC transporter ATP-binding protein VraF -
  EKM74_RS12220 vraG 2305306..2307195 (+) 1890 WP_000143615.1 ABC transporter permease VraG -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 26065.87 Da        Isoelectric Point: 4.3563

>NTDB_id=61637 EKM74_RS12205 WP_001166500.1 2302704..2303378(+) (braR) [Staphylococcus aureus strain TUM9463]
MQILLVEDDNTLFQELKKELEQWDFNVAGIEDFGKVMDTFESFNPEIVILDVQLPKYDGFYWCRKMREVSNVPILFLSSR
DNPMDQVMSMELGADDYMQKPFYTNVLIAKLQAIYRRVYEFTAEEKRTLTWQDAVVDLSKDSIQKGDDTIFLSKTEMIIL
EILITKKNQIVSRDTIITALWDDEAFVSDNTLTVNVNRLRKKLSEISMDSAIETKVGKGYMAHE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=61637 EKM74_RS12205 WP_001166500.1 2302704..2303378(+) (braR) [Staphylococcus aureus strain TUM9463]
ATGCAAATACTACTAGTAGAAGATGACAATACTTTGTTTCAAGAATTGAAAAAAGAATTAGAACAATGGGATTTTAATGT
TGCTGGTATTGAAGATTTCGGCAAAGTAATGGATACATTTGAAAGTTTTAATCCTGAAATTGTTATATTGGATGTTCAAT
TACCTAAATATGATGGGTTTTATTGGTGCAGAAAAATGAGAGAAGTTTCCAACGTACCAATATTATTTTTATCATCTCGT
GATAATCCAATGGATCAAGTGATGAGTATGGAACTTGGCGCAGATGATTATATGCAAAAACCTTTCTATACCAATGTATT
AATTGCTAAATTACAAGCGATTTATCGTCGTGTCTATGAGTTTACAGCTGAAGAAAAACGTACATTGACTTGGCAAGATG
CTGTCGTTGATCTATCAAAAGATAGTATACAAAAAGGTGACGATACGATTTTTCTATCCAAAACAGAAATGATTATATTA
GAAATTCTTATTACCAAAAAAAATCAAATCGTTTCGAGAGATACAATTATCACTGCATTATGGGATGATGAAGCATTTGT
TAGTGATAATACGTTAACAGTAAATGTGAATCGTTTACGAAAAAAATTATCTGAAATTAGTATGGATAGTGCAATCGAAA
CAAAAGTAGGAAAAGGATATATGGCTCATGAATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(149-221)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q99VW2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

40.455

98.214

0.397

Multiple sequence alignment